Výsledky vyhledávání - "Jonathan Fretthold"

p27Kip1 and Cyclin Dependent Kinase 2 Regulate Passage Through the Restriction Point

Autor: Jonathan Fretthold, Masahiro Hitomi, Jyoti A. Harwalkar, Ke Yang, Dennis W. Stacey, Yang Guo

Publikováno v: Cell Cycle. 5:2281-2289

When quiescent cells are stimulated to reenter the cell cycle, growth factors are required only until the restriction point in G(1) phase. After this point the cell no longer requires growth factors, proliferative signaling molecules, or even protein

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e0315ccbc96b4b1773f81527df87766
https://doi.org/10.4161/cc.5.19.3318

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Glycogen synthase kinase 3 has a limited role in cell cycle regulation of cyclin D1 levels

Autor: Jyoti A. Harwalkar, Ke Yang, Masahiro Hitomi, Jonathan Fretthold, William C. Stacey, Dennis W. Stacey, Yang Guo

Publikováno v: BMC Cell Biology, Vol 7, Iss 1, p 33 (2006)
BMC Cell Biology

Background The expression level of cyclin D1 plays a vital role in the control of proliferation. This protein is reported to be degraded following phosphorylation by glycogen synthase kinase 3 (GSK3) on Thr-286. We recently showed that phosphorylatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7063cef6c62966bddcd91f46e24a620
http://www.biomedcentral.com/1471-2121/7/33

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