Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Jonathan Franca-Koh"'
Autor:
Jonathan Franca-Koh
Publikováno v:
Cancer Prevention Research. 15:IA009-IA009
The Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Programs at the National Institutes of Health (NIH) serve as one of the largest sources of early-stage capital for technology commercialization in the United
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::076d688e1c82a15441b3a61c7900722c
https://doi.org/10.1158/1940-6215.tacpad22-ia009
https://doi.org/10.1158/1940-6215.tacpad22-ia009
Autor:
Stefan Wuchty, Arnaud Ceol, James Vlasblom, Sadhna Phanse, Patrick Aloy, Roman Häuser, Ashwani Kumar, Jonathan Franca-Koh, Mohan Babu, Rembert Pieper, Suman B. Pakala, Roland Arnold, Gabriella Siszler, Patricia Sikorski, Peter Uetz, Seesandra V. Rajagopala, Andrew Emili, Roberto Mosca
Publikováno v:
Nature Biotechnology; Vol 32
Nature biotechnology
Nature biotechnology
Efforts to map the Escherichia coli interactome have identified several hundred macromolecular complexes, but direct binary protein-protein interactions (PPIs) have not been surveyed on a large scale. Here we performed yeast two-hybrid screens of 3,3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7acf2ad5aa6c75cef91d3461b28547ff
Autor:
C. David Jones, Mariam Eljanne, Nastaran Z. Kuhn, Nicole M. Moore, Larry A. Nagahara, Katrina I. Theisz, Sean E. Hanlon, Ilya Ponomarev, Jodi Basner, Jonathan Franca-Koh, Pawel Sulima, Michael G. Espey, Karen Jo, Unni Jensen, Joshua D. Schnell
Publikováno v:
Research Evaluation
Development of effective quantitative indicators and methodologies to assess the outcomes of cross-disciplinary collaborative initiatives has the potential to improve scientific program management and scientific output. This article highlights an exa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c91beaacb36a49f21bdeee4148c18ad
https://doi.org/10.1093/reseval/rvt025
https://doi.org/10.1093/reseval/rvt025
Autor:
Jonathan Franca-Koh, Martijn C. Nawijn, Jos Jonkers, Hanneke van der Gulden, Anton Berns, John Zevenhoven, Renée van Amerongen
Publikováno v:
Genes & Development, 19(4), 425-430. COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT
Wnt-signal transduction through β-catenin is thought to require the inhibition of GSK3 by Frat/GBP. To investigate the role of Frat in mammalian development, we have generated mice with targeted mutations in all three murine Frat homologs. We show t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c14bf41cea1e4db659b6eb216b26a03
https://research.rug.nl/en/publications/013afbca-95f7-4ac6-b2bc-10d48d93a8b4
https://research.rug.nl/en/publications/013afbca-95f7-4ac6-b2bc-10d48d93a8b4
Autor:
Jonathan Ryves, Matthew J. Smalley, Adrian J. Harwood, Marie-Therese Webster, Robin S.B. Williams, Trevor Clive Dale, Margaret Yeo, Rana Dajani, Elizabeth Fraser, Christopher A. Richardson, Neville Young, Laurence H. Pearl, Jonathan Franca-Koh
Publikováno v:
Journal of Biological Chemistry. 277:2176-2185
Glycogen synthase kinase-3 (GSK-3) is a key component of several signaling pathways including those regulated by Wnt and insulin ligands. Specificity in GSK-3 signaling is thought to involve interactions with scaffold proteins that localize GSK-3 reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77a1def7066b7355adee5876800bd763
https://doi.org/10.1074/jbc.m109462200
https://doi.org/10.1074/jbc.m109462200
Publikováno v:
Nature Cell Biology. 9:15-17
New studies reveal the dynamic accumulation of phosphatidylinositol (3,4,5) trisphosphate (PtdIns(3,4,5)P3) at the leading edge of primary neutrophils during chemotaxis. They also demonstrate that SHIP1, rather than phosphatase and tensin homologue (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a93d218e9a2c2330af5d85ddf6fe7b8
https://doi.org/10.1038/ncb0107-15
https://doi.org/10.1038/ncb0107-15
Publisher Summary Much of our current understanding of chemotaxis-signaling pathways through G-protein-coupled receptors (GPCRs) is derived from studies on the social amoeba, Dictyostelium discoideum, and mammalian neutrophils. Chemotaxis is the dire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca9b5501207598d46b485ce5625d08f3
https://doi.org/10.1016/b978-0-12-374145-5.00207-2
https://doi.org/10.1016/b978-0-12-374145-5.00207-2
Autor:
Peter N. Devreotes, Cathryn Kabacoff, Yuan Xiong, Douglas N. Robinson, Jonathan Franca-Koh, Pablo A. Iglesias
Publikováno v:
BMC Systems Biology
BMC Systems Biology, Vol 4, Iss 1, p 33 (2010)
BMC Systems Biology, Vol 4, Iss 1, p 33 (2010)
Background The ability of a cell to change shape is crucial for the proper function of many cellular processes, including cell migration. One type of cell migration, referred to as amoeboid motility, involves alternating cycles of morphological expan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::092816214d561ecfea8f54aefb85de01
https://pubmed.ncbi.nlm.nih.gov/20334652
https://pubmed.ncbi.nlm.nih.gov/20334652
Autor:
Jonathan Franca-Koh, Yoichiro Kamimura, Yu Long, Peter N. Devreotes, Jane Borleis, michelle tang, Stacey Willard, Kristen F. Swaney, Meghdad Rahdar, Huaqing Cai
Publikováno v:
The FASEB Journal. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91c90744eed0ea04554d21a5d858a324
https://doi.org/10.1096/fasebj.23.1_supplement.320.3
https://doi.org/10.1096/fasebj.23.1_supplement.320.3
Autor:
Jonathan Franca-Koh, Yuan Xiong, Pablo A. Iglesias, Ross M. Bickford, David A. Knecht, Peter N. Devreotes, Yu Long, Mei Yu Chen, Linnan Tang
In a forward genetic screen for chemotaxis mutants in Dictyostelium discoideum, we identified a loss-of-function mutation, designated tsunami, encoding a homolog of the Fused kinase. Cells lacking tsuA function could not effectively perform chemotaxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a154e8189d8f617fbc41ce882d3a09d9
https://europepmc.org/articles/PMC2518819/
https://europepmc.org/articles/PMC2518819/