Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Jonathan Fintzi"'
Autor:
Bo Zhang, Youyi Fong, Jonathan Fintzi, Eric Chu, Holly E. Janes, Avi Kenny, Marco Carone, David Benkeser, Lars W. P. van der Laan, Weiping Deng, Honghong Zhou, Xiaowei Wang, Yiwen Lu, Chenchen Yu, Bhavesh Borate, Haiyan Chen, Isabel Reeder, Lindsay N. Carpp, Christopher R. Houchens, Karen Martins, Lakshmi Jayashankar, Chuong Huynh, Carl J. Fichtenbaum, Spyros Kalams, Cynthia L. Gay, Michele P. Andrasik, James G. Kublin, Lawrence Corey, Kathleen M. Neuzil, Frances Priddy, Rituparna Das, Bethany Girard, Hana M. El Sahly, Lindsey R. Baden, Thomas Jones, Ruben O. Donis, Richard A. Koup, Peter B. Gilbert, Dean Follmann, On behalf of the United States Government (USG) COVID-19 Immune Assays Team, Moderna, Inc. Team, Coronavirus Vaccine Prevention Network (CoVPN)/Coronavirus Efficacy (COVE) Team, USG/CoVPN Biostatistics Team
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract In the phase 3 Coronavirus Efficacy (COVE) trial (NCT04470427), post-dose two Ancestral Spike-specific binding (bAb) and neutralizing (nAb) antibodies were shown to be correlates of risk (CoR) and of protection against Ancestral-lineage COVI
Externí odkaz:
https://doaj.org/article/3b5ac665acef48f6bef0aa0502ebe57b
Autor:
Dean Follmann, Meagan P. O’Brien, Jonathan Fintzi, Michael P. Fay, David Montefiori, Allyson Mateja, Gary A. Herman, Andrea T. Hooper, Kenneth C. Turner, Kuo- Chen Chan, Eduardo Forleo-Neto, Flonza Isa, Lindsey R. Baden, Hana M. El Sahly, Holly Janes, Nicole Doria-Rose, Jacqueline Miller, Honghong Zhou, Weiping Dang, David Benkeser, Youyi Fong, Peter B. Gilbert, Mary Marovich, Myron S. Cohen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
Abstract While new vaccines for SARS-CoV-2 are authorized based on neutralizing antibody (nAb) titer against emerging variants of concern, an analogous pathway does not exist for preventative monoclonal antibodies. In this work, nAb titers were asses
Externí odkaz:
https://doaj.org/article/f53522c4468546fb9a6f21698f892bd1
Autor:
Anthony L Guerrerio, Allyson Mateja, Gretchen MacCarrick, Jonathan Fintzi, Erica Brittain, Pamela A Frischmeyer-Guerrerio, Harry C Dietz
Publikováno v:
PLoS ONE, Vol 19, Iss 3, p e0298272 (2024)
BackgroundHypermobile Ehlers-Danlos syndrome is a heritable connective tissue disorder associated with generalized joint hypermobility but also other multisystem comorbidities, many of which may be exacerbated during a viral illness or after a vaccin
Externí odkaz:
https://doaj.org/article/d1a1d0a81c854553b03fdef512895fec
Autor:
Christina Yek, MD, Jing Wang, MS, Jonathan Fintzi, PhD, Alex G. Mancera, MS, Michael B. Keller, MD, Sarah Warner, MPH, Sameer S. Kadri, MD
Publikováno v:
Critical Care Explorations, Vol 5, Iss 12, p e1021 (2023)
IMPORTANCE:. Many U.S. State crisis standards of care (CSC) guidelines incorporated Sequential Organ Failure Assessment (SOFA), a sepsis-related severity score, in pandemic triage algorithms. However, SOFA performed poorly in COVID-19. Although disea
Externí odkaz:
https://doaj.org/article/94e490d47eb540e4b92b00a3dea45ed0
Autor:
Carrie M. Long, Paul A. Beare, Diane C. Cockrell, Jonathan Fintzi, Mahelat Tesfamariam, Carl I. Shaia, Robert A. Heinzen
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-14 (2021)
Abstract Coxiella burnetii is the bacterial causative agent of the zoonosis Q fever. The current human Q fever vaccine, Q-VAX®, is a fixed, whole cell vaccine (WCV) licensed solely for use in Australia. C. burnetii WCV administration is associated w
Externí odkaz:
https://doaj.org/article/d0529c4e3ca2440ab6147266ba854488
Autor:
Samantha G. Dean, Emily E. Ricotta, Jonathan Fintzi, Yi Ling Lai, Sameer S. Kadri, Kenneth N. Olivier, Adrian Zelazny, D. Rebecca Prevots
Publikováno v:
Emerging Infectious Diseases, Vol 26, Iss 9, Pp 2243-2246 (2020)
We studied 31 US healthcare facilities to characterize trends in mycobacterial testing. During 2009–2015, testing for acid-fast bacilli increased 3.2% annually, and prevalence of pathogenic nontuberculous mycobacteria increased 4.5% annually. These
Externí odkaz:
https://doaj.org/article/36d39347b1be484ba3c2a9d90d48a7a6
Autor:
Michael S. Abers, Ottavia M. Delmonte, Emily E. Ricotta, Jonathan Fintzi, Danielle L. Fink, Adriana A. Almeida de Jesus, Kol A. Zarember, Sara Alehashemi, Vasileios Oikonomou, Jigar V. Desai, Scott W. Canna, Bita Shakoory, Kerry Dobbs, Luisa Imberti, Alessandra Sottini, Eugenia Quiros-Roldan, Francesco Castelli, Camillo Rossi, Duilio Brugnoni, Andrea Biondi, Laura Rachele Bettini, Mariella D’Angio’, Paolo Bonfanti, Riccardo Castagnoli, Daniela Montagna, Amelia Licari, Gian Luigi Marseglia, Emily F. Gliniewicz, Elana Shaw, Dana E. Kahle, Andre T. Rastegar, Michael Stack, Katherine Myint-Hpu, Susan L. Levinson, Mark J. DiNubile, Daniel W. Chertow, Peter D. Burbelo, Jeffrey I. Cohen, Katherine R. Calvo, John S. Tsang, NIAID COVID-19 Consortium, Helen C. Su, John I. Gallin, Douglas B. Kuhns, Raphaela Goldbach-Mansky, Michail S. Lionakis, Luigi D. Notarangelo
Publikováno v:
JCI Insight, Vol 6, Iss 1 (2021)
Immune and inflammatory responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) contribute to disease severity of coronavirus disease 2019 (COVID-19). However, the utility of specific immune-based biomarkers to predict clinical outc
Externí odkaz:
https://doaj.org/article/feaeec76ff49437f8d320c0de85e7c30
Publikováno v:
PLoS Pathogens, Vol 16, Iss 12, p e1009092 (2020)
Yersinia pestis can be transmitted by fleas during the first week after an infectious blood meal, termed early-phase or mass transmission, and again after Y. pestis forms a cohesive biofilm in the flea foregut that blocks normal blood feeding. We com
Externí odkaz:
https://doaj.org/article/2d0c2e5169e5446393d870f21c694d14
Autor:
Lori E. Dodd, Aneesh K. Mehta, Anuradha Ganesan, Susan McLellan, Jonathan Fintzi, Maria G. Frank, Pablo Tebas, Tyler Bonnett, Daniel A. Sweeney, Nikhil Huprikar
Publikováno v:
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Background The Adaptive Coronavirus Disease 2019 (COVID-19) Treatment Trial-1 (ACTT-1) found that remdesivir therapy hastened recovery in patients hospitalized with COVID-19, but the pathway for this improvement was not explored. We investigated how
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c347ff0c9ff5e9a1925c84eac778bb12
https://doi.org/10.1093/cid/ciab712
https://doi.org/10.1093/cid/ciab712
Autor:
Jennifer A. Bohl, Sreyngim Lay, Sophana Chea, Vida Ahyong, Daniel M. Parker, Shannon Gallagher, Jonathan Fintzi, Somnang Man, Aiyana Ponce, Sokunthea Sreng, Dara Kong, Fabiano Oliveira, Katrina Kalantar, Michelle Tan, Liz Fahsbender, Jonathan Sheu, Norma Neff, Angela M. Detweiler, Christina Yek, Sokna Ly, Rathanak Sath, Chea Huch, Hok Kry, Rithea Leang, Rekol Huy, Chanthap Lon, Cristina M. Tato, Joseph L. DeRisi, Jessica E. Manning
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(11)
Significance Metagenomic pathogen sequencing offers an unbiased approach to characterizing febrile illness. In resource-scarce settings with high biodiversity, it is critical to identify disease-causing pathogens in order to understand burden and to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e096514ffe275771301cfc03d88cfa3
https://pubmed.ncbi.nlm.nih.gov/35238677
https://pubmed.ncbi.nlm.nih.gov/35238677