Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Jonathan Ferrand"'
Autor:
Jonathan Ferrand, Nathan P. Croft, Geneviève Pépin, Kerrilyn R. Diener, Di Wu, Niamh E. Mangan, John Pedersen, Mark A. Behlke, John D. Hayball, Anthony W. Purcell, Richard L. Ferrero, Michael P. Gantier
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
Murine models of Salmonella enterica serovar Typhimurium infection are one of the commonest tools to study host-pathogen interactions during bacterial infections. Critically, the outcome of S. Typhimurium infection is impacted by the genetic backgrou
Externí odkaz:
https://doaj.org/article/7e5861957058486b9b9cb60d528b59f8
Autor:
Geneviève Pépin, Charlotte Nejad, Jonathan Ferrand, Belinda J. Thomas, H. James Stunden, Elaine Sanij, Chwan-Hong Foo, Cameron R. Stewart, Jason E. Cain, Philip G. Bardin, Bryan R. G. Williams, Michael P. Gantier
Publikováno v:
mBio, Vol 8, Iss 5 (2017)
ABSTRACT Inflammatory responses, while essential for pathogen clearance, can also be deleterious to the host. Chemical inhibition of topoisomerase 1 (Top1) by low-dose camptothecin (CPT) can suppress transcriptional induction of antiviral and inflamm
Externí odkaz:
https://doaj.org/article/1854a7e1960c44029afa2f6f6b8c9dcb
Autor:
Jonathan Ferrand, Danièle Noël, Philippe Lehours, Martina Prochazkova-Carlotti, Lucie Chambonnier, Armelle Ménard, Francis Mégraud, Christine Varon
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19569 (2011)
Bone marrow-derived mesenchymal stem cells (MSC) have the ability to differentiate into a variety of cell types and are a potential source for epithelial tissue repair. Several studies have demonstrated their ability to repopulate the gastrointestina
Externí odkaz:
https://doaj.org/article/8dcdd1ac7441419cad0d98f2ea2bc334
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e29007 (2011)
The role of bone marrow-derived mesenchymal stem cells (MSC) in the physiology of the gastrointestinal tract epithelium is currently not well established. These cells can be recruited in response to inflammation due to epithelial damage, home, and pa
Externí odkaz:
https://doaj.org/article/47fff6487c0b403a9c55b6a9c60f7d9c
Autor:
Cheryl Keech, Vicki E Miller, Barbara Rizzardi, Christopher Hoyle, Melinda J Pryor, Jonathan Ferrand, Ken Solovay, Marcel Thalen, Stephanie Noviello, Peter Goldstein, Andrew Gorringe, Breeze Cavell, Qiushui He, Alex-Mikael Barkoff, Keith Rubin, Camille Locht
Publikováno v:
The Lancet. 401:843-855
Autor:
Richard Ferrero, Le Son Tran, Le Ying, Kimberley D'Costa, Georgie Wray-McCann, Genevieve Kerr, Lena Le, Cody Allison, Jonathan Ferrand, Hassan Chaudhry, Jack Emery, Amanda De Paoli, Sarah Creed, Maria Kaparakis-Liaskos, Julia Como, Jennifer Dowling, Priscilla Johanesen, Thomas Kufer, John Pedersen, Ashley Mansell, Dana Philpott, Kirstin Elgass, Helen Abud, Ueli Nachbur, Ben Croker, Seth Masters
The interleukin-1 family members, IL-1β and IL-18, are processed into their biologically active forms by multi-protein complexes, known as inflammasomes. Although the inflammasome pathways that mediate IL-1β processing in myeloid cells have been we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9314f6534a03a32b69f2e9fe20d77999
https://doi.org/10.21203/rs.3.rs-49701/v1
https://doi.org/10.21203/rs.3.rs-49701/v1
Autor:
Marjorie M. Walker, Jonathan Ferrand, Le Son Tran, San Sui Lim, Hassan Mohammad Chaudhry, Gregory T. Moore, Michelle Chonwerawong, Anouk Dev, Mario Milco D'Elios, Prithi S. Bhathal, Dana J. Philpott, Brendan J. Jenkins, Thomas A. Kufer, Chloe Higgins, Richard L. Ferrero, William Sievert
Background & Aims Helicobacter pylori induces strong inflammatory responses that are directed at clearing the infection, but if not controlled, these responses can be harmful to the host. We investigated the immune-regulatory effects of the innate im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edc1bf3248d1dfdb41f8b2af4b01528a
http://hdl.handle.net/2158/1245173
http://hdl.handle.net/2158/1245173
Autor:
A. De Paoli, Kimberley D'Costa, Kirstin Elgass, S. Creed, Thomas A. Kufer, J. Como, Genevieve Kerr, Dana J. Philpott, Jennifer K. Dowling, Jonathan Ferrand, Ashley Mansell, Seth L. Masters, Ben A. Croker, Richard L. Ferrero, Le Son Tran, J. Emery, L. Ying, Ueli Nachbur, C. C. Allison, G. Wray-McCann, J. S. Pedersen, P. A. Johanesen, Helen E. Abud, L. Le, Maria Kaparakis-Liaskos, H. Chaudhry
The interleukin-1 family members, IL-1β and IL-18, are processed into their biologically active forms by multi-protein complexes, known as inflammasomes. Although the inflammasome pathways that mediate IL-1β processing in myeloid cells have been ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f39bc94b8fbb0d8755ecfda9b036d5af
Autor:
Charlotte Nejad, Genevieve Pepin, Michael P. Gantier, Bryan R.G. Williams, Jonathan Ferrand, Kate McArthur, Philip G. Bardin, Belinda J. Thomas
Publikováno v:
Nucleic Acids Research
Acridine dyes, including proflavine and acriflavine, were commonly used as antiseptics before the advent of penicillins in the mid-1940s. While their mode of action on pathogens was originally attributed to their DNA intercalating activity, work in t
Autor:
Veit Hornung, Genevieve Pepin, Michael P. Gantier, Klara Höning, Jonathan Ferrand, Mark A. Behlke, Jason E. Cain, Daniel J. Gough, W. Samantha N. Jayasekara, Bryan R.G. Williams
Publikováno v:
Nucleic Acids Research
ResearcherID
ResearcherID
Gene-recombinase technologies, such as Cre/loxP-mediated DNA recombination, are important tools in the study of gene function, but have potential side effects due to damaging activity on DNA. Here we show that DNA recombination by Cre instigates a ro