Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Jonathan Fenn"'
Autor:
Alexander R. Bennett, Iris Mair, Andrew Muir, Hannah Smith, Larisa Logunova, Andrew Wolfenden, Jonathan Fenn, Ann E. Lowe, Janette E. Bradley, Kathryn J. Else, David J. Thornton
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Mucin protein glycosylation is important in determining biological properties of mucus gels, which form protective barriers at mucosal surfaces of the body such as the intestine. Ecological factors including: age, sex, and diet can change mu
Externí odkaz:
https://doaj.org/article/ac89f561e69d45c38002ffb7599e043b
Autor:
Iris Mair, Jonathan Fenn, Andrew Wolfenden, Ann E Lowe, Alex Bennett, Andrew Muir, Jacob Thompson, Olive Dieumerci, Larisa Logunova, Susanne Shultz, Janette E Bradley, Kathryn J Else
Publikováno v:
PLoS Pathogens, Vol 20, Iss 4, p e1012119 (2024)
Laboratory model organisms have provided a window into how the immune system functions. An increasing body of evidence, however, suggests that the immune responses of naive laboratory animals may differ substantially to those of their wild counterpar
Externí odkaz:
https://doaj.org/article/4e1bbbd0da5f4873a3dc7c3561733d58
Autor:
Jonathan Fenn, Christopher Taylor, Sarah Goertz, Klara M. Wanelik, Steve Paterson, Mike Begon, Joe Jackson, Jan Bradley
Publikováno v:
BMC Microbiology, Vol 23, Iss 1, Pp 1-17 (2023)
Abstract Mammalian gastrointestinal microbiomes are highly variable, both within individuals and across populations, with changes linked to time and ageing being widely reported. Discerning patterns of change in wild mammal populations can therefore
Externí odkaz:
https://doaj.org/article/f09f115982554585a1478c1ab8424558
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract The objective of this study was to assess the diagnostic value of plasma neutrophil gelatinase-associated lipocalin (pNGAL) for the early diagnosis of acute kidney injury (AKI) in adult patients following cardiac surgery requiring cardiopulm
Externí odkaz:
https://doaj.org/article/90855fb9a9ff465bb360b6b88db723f1
Autor:
Stuart Young, Jonathan Fenn, Elena Arriero, Ann Lowe, Benoit Poulin, Andrew D.C. MacColl, Janette E. Bradley
Publikováno v:
Ecology and Evolution, Vol 10, Iss 24, Pp 13860-13871 (2020)
Abstract Quantitative PCR (qPCR) has been commonly used to measure gene expression in a number of research contexts, but the measured RNA concentrations do not always represent the concentrations of active proteins which they encode. This can be due
Externí odkaz:
https://doaj.org/article/28d9a2b6eba54fad87a09099474ac9ec
Autor:
Sarah Goertz, Alexandre B de Menezes, Richard J Birtles, Jonathan Fenn, Ann E Lowe, Andrew D C MacColl, Benoit Poulin, Stuart Young, Janette E Bradley, Christopher H Taylor
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0222501 (2019)
The composition of the mammalian gut microbiota can be influenced by a multitude of environmental variables such as diet and infections. Studies investigating the effect of these variables on gut microbiota composition often sample across multiple se
Externí odkaz:
https://doaj.org/article/a86f1082dd8c488d94064c42d5b5c90a
Publikováno v:
Clinical Biochemistry. 103:25-28
Manufacturer-provided assay-specific reference intervals may not compensate for between assay differences leading to method related clinical discordance. Not all laboratories, however, assess clinical concordance as part of method comparison studies.
Autor:
Andrew Muir, Alex Bennett, Hannah Smith, Larisa Logunova, Andrew Wolfenden, Jonathan Fenn, Ann E Lowe, Andy Brass, John R Grainger, Joanne E Konkel, Janette E Bradley, Iris Mair, Kathryn J Else
Publikováno v:
Discovery Immunology. 2
The murine bone marrow has a central role in immune function and health as the primary source of leukocytes in adult mice. Laboratory mice provide a human-homologous, genetically manipulable and reproducible model that has enabled an immeasurable vol
Publikováno v:
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine. 58:638-645
Background A large discordance in the diagnosis and potential management of hypothyroidism using Abbott and Roche thyroid assays has been reported recently. The difference in Abbott and Roche thyroid-stimulating hormone (TSH) results in these studies
Autor:
Tejas Kalaria, Jonathan Fenn, Anna Sanders, Alexandra Yates, Christopher Duff, Helen Ashby, Pervaz Mohammed, Clare Ford, Rousseau Gama
Publikováno v:
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 54(7)
We assessed the impact of intact parathyroid hormone (iPTH) and adjusted calcium analyses on Abbott, Roche and Siemens analytical platforms in the diagnosis of normocalcaemic primary hyperparathyroidism (NCPHPT). These assays are used by over 85% of