Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Jonathan F. Arambula"'
Autor:
Yunjie Xu, Yingwei Wang, Jusung An, Adam C. Sedgwick, Mingle Li, Jianlei Xie, Weibin Hu, Jianlong Kang, Sajal Sen, Axel Steinbrueck, Bin Zhang, Lijun Qiao, Swelm Wageh, Jonathan F. Arambula, Liping Liu, Han Zhang, Jonathan L. Sessler, Jong Seung Kim
Publikováno v:
Bioactive Materials, Vol 14, Iss , Pp 76-85 (2022)
An increased demand for iron is a hallmark of cancer cells and is thought necessary to promote high cell proliferation, tumor progression and metastasis. This makes iron metabolism an attractive therapeutic target. Unfortunately, current iron-based t
Externí odkaz:
https://doaj.org/article/d782771aa4954029b1ade144caa4c826
Autor:
Sajal Sen, Miae Won, Matthew S. Levine, Yuvin Noh, Adam C. Sedgwick, Jong Seung Kim, Jonathan L. Sessler, Jonathan F. Arambula
Publikováno v:
Chem Soc Rev
Cancer is the deadliest disease in the world behind heart disease. Sadly, this remains true even as we suffer the ravages of the Covid-19 pandemic. Whilst current chemo- and radiotherapeutic treatment strategies have significantly improved the patien
Autor:
Calvin V. Chau, Sajal Sen, Adam C. Sedgwick, Philip A. Gale, G. Dan Pantos, Sung Kuk Kim, Jung Su Park, Elisa Tomat, Jonathan F. Arambula, Anne E.V. Gorden, Hiroyuki Furuta
Publikováno v:
Chem. 8:587-598
Autor:
Guo-Qing Jin, Calvin V. Chau, Jonathan F. Arambula, Song Gao, Jonathan L. Sessler, Jun-Long Zhang
Publikováno v:
Chemical Society Reviews. 51:6177-6209
In recent years, lanthanide (Ln) porphyrinoids have received increasing attention as theranostics. Broadly speaking, the term 'theranostics' refers to agents designed to allow both disease diagnosis and therapeutic intervention. This Review summarise
Autor:
Garrett L. Reinhard, Selvakumar Jayaraman, Joshua W. Prybil, Jonathan F. Arambula, Kuppuswamy Arumugam
Publikováno v:
Dalton Trans
Unambiguous assignment of redox sites on ferrocene coupled N-heterocyclic carbene gold(I) complexes [(Fc-NHC)(2)Au(I)](+) is critical to gain a greater mechanistic understanding of their activity in a cellular environment. Such information can be gar
Publikováno v:
Current Opinion in Chemical Biology. 73:102277
Autor:
Jingqin Chen, Chengbo Liu, Tridib K. Sarma, Yaguang Ren, Qinchao Sun, Jonathan L. Sessler, Sajal Sen, Calvin V. Chau, Liang Song, Adam C. Sedgwick, Jonathan F. Arambula
Publikováno v:
Chemical Science
Photoacoustic imaging (PAI) relies on the use of contrast agents with high molar absorptivity in the NIR-I/NIR-II region. Expanded porphyrins, synthetic analogues of natural tetrapyrrolic pigments (e.g. heme and chlorophyll), constitute as potentiall
Autor:
Jonathan F. Arambula, Sajal Sen, Jonathan L. Sessler, Adam C. Sedgwick, Vincent M. Lynch, Mark W. Perrin
Publikováno v:
Chemical Science. 12:7547-7553
Recent decades have witnessed the emergence of Au(i) bis-N-heterocyclic carbenes (NHCs) as potential anticancer agents. However, these systems exhibit little interaction with serum proteins (e.g., human serum albumin), which presumably impacts their
Autor:
Jayaraman Selvakumar, Esther Y. Maier, Kuppuswamy Arumugam, Vincent M. Lynch, Stephanie Hufnagel, Jonathan F. Arambula, Sajal Sen, Jennie E. DeVore, Jonathan L. Sessler, Zhengrong Cui, Isaiah Aguilar
Publikováno v:
J Am Chem Soc
Immunogenic cell death (ICD) is a way of reengaging the tumor-specific immune system. ICD can be induced by treatment with chemotherapeutics. However, only a limited number of drugs and other treatment modalities have been shown to elicit the biomark
Publikováno v:
Chem
Summary Drawing inspiration from nature today remains a time-honored means of discovering the therapies of tomorrow. Porphyrins, the so-called “pigments of life” have played a key role in this effort due to their diverse and unique properties. Th