Zobrazeno 1 - 10
of 309
pro vyhledávání: '"Jonathan F. Lovell"'
Autor:
Kazutoyo Miura, Bingbing Deng, Ragavan Varadharajan Suresh, Yonas T. Gebremicale, Luwen Zhou, Thao P. Pham, Kyle Roche, Ababacar Diouf, Jonathan F. Lovell, Jean-Philippe Julien, Carole A. Long
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract Malaria remains a global health problem, and the standard membrane feeding assay (SMFA) is a key functional assay for development of new interventions to stop malaria transmission from human to mosquito. For SMFA, media with ~ 10% of human s
Externí odkaz:
https://doaj.org/article/32f6c09562ee4cb4bb5405b3c67bfa21
Autor:
Muyang Yang, Jie Zhou, Liseng Lu, Deqiang Deng, Jing Huang, Zijian Tang, Xiujuan Shi, Pui‐Chi Lo, Jonathan F. Lovell, Yongfa Zheng, Honglin Jin
Publikováno v:
Exploration, Vol 4, Iss 6, Pp n/a-n/a (2024)
Abstract Because therapeutic cancer vaccines can, in theory, eliminate tumor cells specifically with relatively low toxicity, they have long been considered for application in repressing cancer progression. Traditional cancer vaccines containing a si
Externí odkaz:
https://doaj.org/article/0a5a65f20c9c4bbab5f8c56d5fd8568a
Autor:
Yajie Sun, Yan Hu, Yuanyuan Geng, Chao Wan, Yang Liu, Yifei Liao, Xiujuan Shi, Jonathan F. Lovell, Kunyu Yang, Honglin Jin
Publikováno v:
Exploration, Vol 4, Iss 5, Pp n/a-n/a (2024)
Abstract Vaccine‐based therapeutics for cancers face several challenges including lack of immunogenicity and tumor escape pathways for single antigen targets. It has been reported that radiotherapy has an in situ vaccine effect that provides tumor
Externí odkaz:
https://doaj.org/article/74fcb04619de40a0ac12a40ffa16577a
Autor:
Caiqian Wang, Yuanyuan Geng, Haoran Wang, Zeheng Ren, Qingxiu Hou, An Fang, Qiong Wu, Liqin Wu, Xiujuan Shi, Ming Zhou, Zhen F Fu, Jonathan F Lovell, Honglin Jin, Ling Zhao
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 6, Pp 1451-1483 (2024)
Abstract Although protein subunit vaccines generally have acceptable safety profiles with precise antigenic content, limited immunogenicity can lead to unsatisfactory humoral and cellular immunity and the need for vaccine adjuvants and delivery syste
Externí odkaz:
https://doaj.org/article/a34d3dfc3d324d818a21353b94f3adc5
Autor:
Zihan Deng, Binghui Li, Muyang Yang, Lisen Lu, Xiujuan Shi, Jonathan F. Lovell, Xiantao Zeng, Weidong Hu, Honglin Jin
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract Immunogenic cell death (ICD) plays a crucial role in triggering the antitumor immune response in the tumor microenvironment (TME). Recently, considerable attention has been dedicated to ferroptosis, a type of ICD that is induced by intracell
Externí odkaz:
https://doaj.org/article/8be82e8ec6d54c76b62e3fe9f9f06d99
Autor:
Annemart Koornneef, Kanika Vanshylla, Gijs Hardenberg, Lucy Rutten, Nika M. Strokappe, Jeroen Tolboom, Jessica Vreugdenhil, Karin Feddes-de Boer, Aditya Perkasa, Sven Blokland, Judith A. Burger, Wei-Chiao Huang, Jonathan F. Lovell, Danielle van Manen, Rogier W. Sanders, Roland C. Zahn, Hanneke Schuitemaker, Johannes P. M. Langedijk, Frank Wegmann
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract One of the strategies towards an effective HIV-1 vaccine is to elicit broadly neutralizing antibody responses that target the high HIV-1 Env diversity. Here, we present an HIV-1 vaccine candidate that consists of cobalt porphyrin-phospholipi
Externí odkaz:
https://doaj.org/article/b47f9ae471c641c184638edf81cb1133
Publikováno v:
mSphere, Vol 9, Iss 7 (2024)
ABSTRACT Epitopes from the Candida cell surface proteins Fba and Met6 are putative vaccine targets for invasive candidiasis. Here, we describe a Candida vaccine approach in which short peptides derived from Fba and Met6 are used in spontaneous nanoli
Externí odkaz:
https://doaj.org/article/c3899d1ee21f4675b5279d11a863fc12
Autor:
Jonathan F. Lovell, Kazutoyo Miura, Yeong Ok Baik, Chankyu Lee, Jeong-Yoon Lee, Young-Shin Park, Ingi Hong, Jung Hyuk Lee, Taewoo Kim, Sang Hwan Seo, Jae-Ouk Kim, Manki Song, Chung-Jong Kim, Jae-Ki Choi, Jieun Kim, Eun Ju Choo, Jung-Hyun Choi
Publikováno v:
International Journal of Infectious Diseases, Vol 138, Iss , Pp 73-80 (2024)
Objective: EuCorVac-19 (ECV-19), an adjuvanted liposome-displayed receptor binding domain (RBD) COVID-19 vaccine, previously reported interim Phase 2 trial results showing induction of neutralizing antibodies 3 weeks after prime-boost immunization. T
Externí odkaz:
https://doaj.org/article/92e258add5c642e19060a10330ea19f8
Autor:
Shiqi Zhou, Karl O.A. Yu, Moustafa T. Mabrouk, Dushyant Jahagirdar, Wei-Chiao Huang, Julio A. Guerra, Xuedan He, Joaquin Ortega, Steven T. Poole, Eric R. Hall, Oscar G. Gomez-Duarte, Milton Maciel, Jr., Jonathan F. Lovell
Publikováno v:
Biomedical Journal, Vol 46, Iss 6, Pp 100588- (2023)
Background: Enterotoxigenic Escherichia coli (ETEC) strains cause infectious diarrhea and colonize host intestine epithelia via surface-expressed colonization factors. Colonization factor antigen I (CFA/I), a prevalent ETEC colonization factor, is a
Externí odkaz:
https://doaj.org/article/ff69563edaf3491ea5971bdac0a3cd29
Autor:
Boyang Sun, Georgios Paraskevopoulos, Jiwei Min, Robert Rossdeutcher, Sanjana Ghosh, Breandan Quinn, Meng‐Hsuan Lin, Debanjan Sarkar, Dinesh Sukumaran, Yuefei Wang, Kateřina Vávrová, Jonathan F. Lovell, Yumiao Zhang
Publikováno v:
Advanced Science, Vol 10, Iss 29, Pp n/a-n/a (2023)
Abstract Topical chemotherapy approaches are relevant for certain skin cancer treatments. This study observes that cabazitaxel (CTX), a broad‐spectrum second‐generation taxane cytotoxic agent, can be dissolved in α‐tocopherol at high concentra
Externí odkaz:
https://doaj.org/article/a82d9f63c0f8496e8d4524c280b3ca62