Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jonathan Essex"'
Autor:
Eleanor G. Seaby, Steven Turner, David J. Bunyan, Fariba Seyed‐Rezai, Jonathan Essex, Rodney D. Gilbert, Sarah Ennis
Publikováno v:
Clinical Genetics. 103:214-218
Renal Fanconi syndrome (RFS) is a generalised disorder of the proximal convoluted tubule. Many genes have been associated with RFS including those that cause systemic disorders such as cystinosis, as well as isolated RFS. We discuss the case of a 10-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4871a7c58a3b73139b6d5c2d3fb9129c
https://doi.org/10.1111/cge.14235
https://doi.org/10.1111/cge.14235
NOTE - A significant portion of the text from this preprint is drawn from a previous submission (https://doi.org/10.26434/chemrxiv.12967655.v2). This is a later version of the previous submission with a new title and updated results. The Coronavirus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e739b8fe75ef2e2b0555a0c1a9aa10c
https://doi.org/10.26434/chemrxiv-2022-d6b0w
https://doi.org/10.26434/chemrxiv-2022-d6b0w
Water plays an important role in mediating protein-ligand interactions. Water rearrangement upon a ligand binding or modification can be very slow and beyond typical timescales used in molecular dynamics (MD) simulations. Thus, inadequate sampling of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::607b57a25960606b80c4b4684a70d13c
https://doi.org/10.26434/chemrxiv-2022-7s8rb
https://doi.org/10.26434/chemrxiv-2022-7s8rb
Enhanced Grand Canonical Sampling of Occluded Water Sites Using Nonequilibrium Candidate Monte Carlo
Water molecules play a key role in biomolecular systems, particularly when bound at protein-ligand interfaces. Simulation studies are hampered by the relatively long timescales on which water exchange between protein and solvent can take place. Grand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47e1cfa5880306207322118fce63d27b
https://doi.org/10.26434/chemrxiv-2022-7w90m
https://doi.org/10.26434/chemrxiv-2022-7w90m
The Coronavirus Disease of 2019 (COVID-19) is caused by a novel coronavirus known as the Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2). Despite extensive research since the outset of the pandemic, definitive therapeutic agents for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08f49032c7aa62aaf9564e1e6cf2c6e5
https://doi.org/10.26434/chemrxiv.12967655.v2
https://doi.org/10.26434/chemrxiv.12967655.v2