Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jonathan E. Wosen"'
Autor:
Jonathan E. Wosen, Alexandra Ilstad-Minnihan, Julia Y. Co, Wei Jiang, Dhriti Mukhopadhyay, Nielsen Q. Fernandez-Becker, Calvin J. Kuo, Manuel R. Amieva, Elizabeth D. Mellins
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The role of intestinal epithelial cells (IECs) in mucosal tolerance and immunity remains poorly understood. We present a method for inducing MHC class II (MHC-II) in human enteroids, “mini-guts” derived from small intestinal crypt stem cells, and
Externí odkaz:
https://doaj.org/article/3663dc00214340a2a9175c550d4c566d
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
As the primary barrier between an organism and its environment, epithelial cells are well-positioned to regulate tolerance while preserving immunity against pathogens. Class II major histocompatibility complex molecules (MHC class II) are highly expr
Externí odkaz:
https://doaj.org/article/b692ede18a8e4bd1928c82fa0d9a493c
Autor:
Linda L. Yasukawa, Harry B. Greenberg, Manuel R. Amieva, Siyuan Ding, Julia Y. Co, Yanhua Song, Jonathan E. Wosen, Eugene C. Butcher, Calvin J. Kuo, Kevin Brulois, Lili Ren, Elizabeth D. Mellins, Liliana Sánchez-Tacuba, Junliang Pan, Denise M. Monack, Ningguo Feng
Publikováno v:
Gastroenterology
Background & Aims Intestinal microfold (M) cells are a unique subset of intestinal epithelial cells in the Peyer's patches that regulate mucosal immunity, serving as portals for sampling and uptake of luminal antigens. The inability to efficiently de
Autor:
Jianming Qiu, Xuefeng Deng, Safder S. Ganaie, Jonathan E. Wosen, Nancy L. Meyer, Jan E. Carette, Michael Chapman, Wei Zou, John F. Engelhardt, Andreas S. Puschnik, Sirika Pillay, Fang Cheng, Ziying Yan, Kevin E. Brown, Omar Davulcu
Publikováno v:
Journal of Virology
Adeno-associated virus (AAV) entry is determined by its interactions with specific surface glycans and a proteinaceous receptor(s). Adeno-associated virus receptor (AAVR) (also named KIAA0319L) is an essential cellular receptor required for the trans
Autor:
Paloma Marin, Leigh Davis, Jeffrey D. Amack, Jonah P. Zuflacht, Yongchang Ji, Martha J. Marvin, Mark W. Springel, Jamie L. Lahvic, Jonathan E. Wosen, Lara D. Hutson
Publikováno v:
Developmental Biology. 384:166-180
Small heat shock proteins (sHsps) regulate cellular functions not only under stress, but also during normal development, when they are expressed in organ-specific patterns. Here we demonstrate that two small heat shock proteins expressed in embryonic
Autor:
Jonathan E. Wosen, Michael Chapman, Jonathan Diep, Yoshihiro Ishikawa, Jan E. Carette, Claude M. Nagamine, Lucas T. Jae, Nancy L. Meyer, Sirika Pillay, Andreas S. Puschnik, Omar Davulcu
Publikováno v:
Nature. 530(7588)
Adeno-associated virus (AAV) vectors are currently the leading candidates for virus-based gene therapies because of their broad tissue tropism, non-pathogenic nature and low immunogenicity. They have been successfully used in clinical trials to treat
Autor:
Andreas S. Puschnik, Jan E. Carette, Lucas T. Jae, Sirika Pillay, Claude M. Nagamine, Jonathan Diep, Jonathan E. Wosen, Nancy L. Meyer, Yoshihiro Ishikawa, Michael Chapman, Omar Davulcu
Publikováno v:
Nature. 539:456-456
Nature 530, 108–112 (2016); doi:10.1038/nature16465 In this Letter, there is an error in Extended Data Fig. 1b. During preparation of the figure, an error was introduced while copying the flow cytometry plot for ‘HAP1 WT+isotype’ and the y-axis
Autor:
Yoshi Ishikawa, Jonathan E. Wosen, Michael Chapman, Omar Davulco, Nancy L. Meyer, Andreas S. Puschnik, Jonathan Diep, Lucas T. Jae, Sirika Pillay, Claude M. Nagamine, Jan E. Carette
Publikováno v:
Molecular Therapy. 24:S118
Cellular entry of adeno-associated viruses (AAV) is poorly understood, despite the prominent use of AAV vectors in gene therapy for several monogenic diseases. Using an unbiased, haploid genetic screen, we identified critical players in AAV serotype
Autor:
Yoshi Ishikawa, Claude M. Nagamine, Qing Xie, Michael Chapman, Jonathan Diep, Lucas T. Jae, Nancy L. Meyer, Sirika Pillay, Scott M. Stagg, Omar Davulcu, Jan E. Carette, Jonathan E. Wosen, Alex J. Noble, Andreas S. Puschnik
Publikováno v:
Molecular Therapy. 24:S189
Motivated by unsuccessful attempts to observe physical binding between AAV-2 and heterologously expressed domains of previously reported co-receptors, we set out to identify novel protein receptor(s) for AAV2 through an unbiased genome-wide knockout