Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Jonathan E. Wilson"'
Autor:
Emily A. Simonds, Katrina Arlene P. Gobenciong, Jonathan E. Wilson, Michael R. Jiroutek, Nicole R. Nugent, Miranda A. L. van Tilburg
Publikováno v:
Children, Vol 9, Iss 7, p 951 (2022)
Background: There is worldwide consensus that providing secondary prevention to promote resilience and prevent mental health concerns after a disaster is important. However, data supporting this kind of intervention is largely lacking. The current st
Externí odkaz:
https://doaj.org/article/95a634b5499b41978d738c902bb9f17b
Autor:
Archana Bommi-Reddy, Sungmi Park-Chouinard, David N Mayhew, Esteban Terzo, Aparna Hingway, Michael J Steinbaugh, Jonathan E Wilson, Robert J Sims, Andrew R Conery
Publikováno v:
PLoS ONE, Vol 17, Iss 3, p e0262378 (2022)
Therapeutic targeting of the estrogen receptor (ER) is a clinically validated approach for estrogen receptor positive breast cancer (ER+ BC), but sustained response is limited by acquired resistance. Targeting the transcriptional coactivators require
Externí odkaz:
https://doaj.org/article/910a16c22594471fa25f0c86a1e97743
Autor:
Anna S. Gardberg, Francois Brucelle, Robert J. Sims, Nico Cantone, Richard T. Cummings, Florence Poy, Archana Bommi-Reddy, Julian Levell, Jonathan E. Wilson, Chirag Patel, Annissa J. Huhn, Gaurav Patel
Publikováno v:
ACS Med Chem Lett
[Image: see text] The histone acetyltransferases, CREB binding protein (CBP) and EP300, are master transcriptional co-regulators that have been implicated in numerous diseases, such as cancer, inflammatory disorders, and neurodegeneration. A novel, h
Autor:
Archana Bommi-Reddy, Sungmi Park-Chouinard, David N. Mayhew, Esteban Terzo, Aparna Hingway, Michael J. Steinbaugh, Jonathan E. Wilson, Robert J. Sims, Andrew R. Conery
Publikováno v:
PloS one. 17(3)
Therapeutic targeting of the estrogen receptor (ER) is a clinically validated approach for estrogen receptor positive breast cancer (ER+ BC), but sustained response is limited by acquired resistance. Targeting the transcriptional coactivators require
Autor:
Ingrid Almeciga, Costa Salojin, Julian Levell, Anna Gardberg, Patrick Trojer, Lei Cui, Richard D. Cummings, Jennifer Rocnik, Valerie Vivat, Jacob I. Stuckey, Nico Cantone, Florence Poy, Jonathan E. Wilson, Jeffrey Lauer
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundTREX1 is an exonuclease that functions as a negative regulator of innate immunity. TREX1 controls dsDNA sensing in tumor and immune cells by preventing aberrant dsDNA buildup that triggers STING-mediated Type 1 Interferon (IFN) induction le
Autor:
Michael E. Kitto, Jane Malone, David E. Jacobs, Jonathan E. Wilson, Calvin D. Murphy, Sherry L. Dixon
Publikováno v:
Journal of public health management and practice : JPHMP. 28(2)
Context To determine if radon mitigation is needed to protect occupants of multifamily housing, reliable testing procedures are needed. Yet, protocols on how many ground-contact housing units must be tested vary from 10% to 25% to 100%. Objectives To
Autor:
Peter E. Maligres, Jeff Fritzen, Guy R. Humphrey, Yonggang Chen, Zhiguo Jake Song, Jonathan E. Wilson, Carmela Molinaro
Publikováno v:
Organic Process Research & Development. 23:2354-2361
2-(2H-Tetrazol-2-yl)benzoic acid 1 and analogs were prepared via Cu(I) catalyzed C–N coupling of 2-iodo or 2-bromo benzoic acids with 5-(ethylthio)-1H-tetrazole followed by reductive cleavage of the thioether bond. The C–N coupling was regioselec
Publikováno v:
Journal of public health management and practice : JPHMP. 26(1)
Clients receiving weatherization/energy services with an added injury prevention home assessment with modifications/repairs experienced a decline in falls and thus fall-related costs. Interventions in 35 homes were associated with significant reducti
Autor:
Pravien Abeywickrema, Shawn J. Stachel, Tamara D. Cabalu, Anthony T. Ginetti, Yili Chen, Daniel V. Paone, Michael P. Dwyer, Jonathan E. Wilson, Deping Wang, Alejandro Crespo, Jun Lu, Christopher Joseph Sinz, Gregori J. Morriello, Shimin Xu
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 44:128082
A focused SAR study was conducted on a series of N1-substituted pyrazolopyrimidinone PDE2 inhibitors to reveal compounds with excellent potency and selectivity. The series was derived from previously identified internal leads and designed to enhance
Publikováno v:
Journal of Emergency and Critical Care Medicine. 5:25-25