Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Jonathan E. Ploski"'
Autor:
Kanishk Goel, Jonathan E. Ploski
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Manipulating gene expression within and outside the nervous system is useful for interrogating gene function and developing therapeutic interventions for a variety of diseases. Several approaches exist which enable gene manipulation in preclinical mo
Externí odkaz:
https://doaj.org/article/494bbab357fd4f6ab68135be33c5c434
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 19, p 7072 (2020)
Existing memories, when retrieved under certain circumstances, can undergo modification through the protein synthesis-dependent process of reconsolidation. Disruption of this process can lead to the weakening of a memory trace, an approach which is b
Externí odkaz:
https://doaj.org/article/b8da22d338494b5fbbf736bcf9852e01
Autor:
Namrata Kumar, William Stanford, Christopher de Solis, Aradhana, Nigel D. Abraham, Trieu-Mi J. Dao, Sadiqa Thaseen, Anusha Sairavi, Cuauhtemoc Ulises Gonzalez, Jonathan E. Ploski
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
The RNA-guided Cas9 nuclease, from the type II prokaryotic clustered regularly interspersed short palindromic repeats (CRISPR) adaptive immune system, has been adapted by scientists to enable site specific genome editing of eukaryotic cells both in v
Externí odkaz:
https://doaj.org/article/c00296fabbf048b68679861f0354ce20
Autor:
Christopher A. de Solis, Anna A. Morales, Matthew P. Hosek, Alex C. Partin, Jonathan E. Ploski
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
There have been several attempts to identify which RNAs are localized to dendrites; however, no study has determined which RNAs localize to the dendrites following the induction of synaptic activity. We sought to identify all RNA transcripts that loc
Externí odkaz:
https://doaj.org/article/1331f2dcf3ad4cbc933fb1a74fb44fcb
Autor:
Vidita A. Vaidya, Jonathan E. Ploski
Publikováno v:
Biological Psychiatry. 90:109-117
The neurocircuitry that contributes to the pathophysiology of posttraumatic stress disorder and major depressive disorder, psychiatric conditions that exhibit a high degree of comorbidity, likely involves both overlapping and unique structural and fu
Autor:
Joseph A. Zasadzinski, Andreas Zumbuehl, Jeong Eun Shin, Hui Wang, Hejian Xiong, Sven Kroener, Peiyuan Kang, Frederik Neuhaus, Maria O. Ogunyankin, Zhenpeng Qin, Jonathan E. Ploski, Paul A. Slesinger, Xiuying Li, John M. Perish
Publikováno v:
Angew Chem Int Ed Engl
Remote and minimally-invasive modulation of biological systems with light has transformed modern biology and neuroscience. However, light absorption and scattering significantly prevents penetration to deep brain regions. Herein, we describe the use
Autor:
Cory Langreck, Jonathan E. Ploski, Lori Winter, Francesca Di Sole, Dakota A Nerland, Kenneth E. McCarson, Vanja Duric, Mounira Banasr, Miranda M. Roland, Eric Wauson, Eileen Lu, Brad Lamb, Victor Babich, Sarah E. Tague, Ronald S. Duman, Tyler Folkerts
Publikováno v:
Biochemical pharmacology. 190
Clinical reports indicate a bidirectional relationship between mental illness and chronic systemic diseases. However, brain mechanisms linking chronic stress and development of mood disorders to accompanying peripheral organ dysfunction are still not
Autor:
las Fuentes SGd, Owen Ms, Oad S, Miller Jn, Jonathan E. Ploski, Salinas Ce, Galdamez Ma, Pineda Oh, Sandoval A, Hajira Elahi, Roopashri Holehonnur, Perish Jm, Woodard Sw, Solis CAd, Gonzalez Cu
Reconsolidation disruption has been proposed as a method to attenuate pathological memories in disorders such as PTSD. However, studies from our group and others indicate that strong memories are resistant to becoming destabilized following reactivat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7c244047570856d6a199949523f41f4
Autor:
Milica Milivojevic, Jonathan E. Ploski, Michael Tiner, Lily J. Kim, Lauren E. Jones, Dat Vuong, Delvin K. Daison, Saira Alex, Aarron Phensy, Sven Kroener, Roopashri Holehonnur
Publikováno v:
The Journal of Neuroscience. 36:9490-9504
Reconsolidation updating is a form of memory modification in which an existing memory can become destabilized upon retrieval and subsequently be modified via protein-synthesis-dependent reconsolidation. However, not all memories appear to destabilize
Publikováno v:
eNeuro
Visual Abstract
The multitude of neuronal subtypes and extensive interconnectivity of the mammalian brain presents a substantial challenge to those seeking to decipher its functions. While the molecular mechanisms of several neuronal functions r
The multitude of neuronal subtypes and extensive interconnectivity of the mammalian brain presents a substantial challenge to those seeking to decipher its functions. While the molecular mechanisms of several neuronal functions r