Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jonathan E. Grim"'
Mantle cell lymphoma relapsed after autologous stem cell transplantation: a single-center experience
Autor:
Robert E. Richard, Thomas R. Chauncey, Aaron Wu, Jonathan E. Grim, Zhao Ming Dong, Solomon A. Graf, Nicholas Burwick
Publikováno v:
Blood research
Background Autologous stem cell transplantation (autoSCT) can extend remission of mantle cell lymphoma (MCL), but the management of subsequent relapse is challenging. Methods We examined consecutive patients with MCL who underwent autoSCT at Veterans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::464c17f0101a18f8aca332d41cff54d8
https://doi.org/10.5045/br.2020.55.1.57
https://doi.org/10.5045/br.2020.55.1.57
Autor:
Elena Elimova, Jaffer A. Ajani, Howard A. Burris III, Crystal S. Denlinger, Syma Iqbal, Yoon-Koo Kang, YEUL HONG Hong Kim, Keun-Wook Lee, Bruce Lin, Rutika Mehta, Do-Youn Oh, Sun Young Rha, Yong Mi Soel, Lisa Boyken, Jonathan E. Grim, Geoffrey Yuyat Ku
Publikováno v:
Journal of Clinical Oncology. 41:347-347
347 Background: Zanidatamab (zani) is an anti-HER2 bispecific antibody against ECD4 and ECD2 with demonstrated activity and tolerability in a range of HER2-expressing cancers. This Phase (Ph) 2 study (NCT03929666) evaluates zani in combination with c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce811f853441155adacf79cbd5249719
https://doi.org/10.1200/jco.2023.41.4_suppl.347
https://doi.org/10.1200/jco.2023.41.4_suppl.347
Autor:
Luke J. Drury, Brian M. Fissel, Bridget T. Hughes, Adam J. Dupuy, Jonathan E. Grim, Keith R. Loeb, Bruce E. Clurman, Aaron L. Sarver, Sue E. Knoblaugh, Nyka J. Osteen
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
Insertional mutagenesis is a powerful means of identifying cancer drivers in animal models. We used the Sleeping Beauty (SB) transposon/transposase system to identify activated oncogenes in hematologic cancers in wild-type mice and mice that express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64fb0a71cb0b6a76666de9190a94566a
http://link.springer.com/article/10.1038/s41598-019-41805-x
http://link.springer.com/article/10.1038/s41598-019-41805-x
Autor:
Jeffrey J. Delrow, Jherek Swanger, William M. Grady, Keiichi I. Nakayama, Tom Small, Jessica Hespelt, Amanda Hagar, Katherine A. Guthrie, Bruce E. Clurman, Jonathan E. Grim, Sue E. Knoblaugh
Publikováno v:
Molecular and Cellular Biology. 32:2160-2167
Colorectal cancer (CRC) remains a major cause of cancer mortality worldwide. Murine models have yielded critical insights into CRC pathogenesis, but they often fail to recapitulate advanced-disease phenotypes, notably metastasis and chromosomal insta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91f6a84cdcfc44f2fdb2d3ad9392bd45
https://doi.org/10.1128/mcb.00305-12
https://doi.org/10.1128/mcb.00305-12
Autor:
Harry C. Hwang, David W. Russell, Michael P. Gustafson, Roli K. Hirata, Amanda Hagar, Markus Welcker, Bruce E. Clurman, Jherek Swanger, Jonathan E. Grim, Johan Ericsson
Publikováno v:
The Journal of Cell Biology
The SCFFBW7 ubiquitin ligase degrades proteins involved in cell division, growth, and differentiation and is commonly mutated in cancers. The Fbw7 locus encodes three protein isoforms that occupy distinct subcellular localizations, suggesting that ea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d913b092b30c1701d96f3eac0223f5c
https://doi.org/10.1083/jcb.200802076
https://doi.org/10.1083/jcb.200802076
Publikováno v:
Gastroenterology Report
Gastroesophageal cancer is a significant global problem that frequently presents at an incurable stage and has very poor survival with standard chemotherapy approaches. This review will examine the epidemiology and molecular biology of gastroesophage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::af324f7a2a1f52dd8f57ed6c2fa20fc1
https://pubmed.ncbi.nlm.nih.gov/26510453
https://pubmed.ncbi.nlm.nih.gov/26510453
Publikováno v:
Cell and Tissue Research. 325:263-276
Mechanisms controlling epithelial proliferation and differentiation in the prostate have been primarily investigated in mouse models. The regulation of proliferation and differentiation is poorly understood in human prostate epithelial cells. In vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaeac8fc07718e448383c2c83bdb134a
https://doi.org/10.1007/s00441-005-0093-0
https://doi.org/10.1007/s00441-005-0093-0
Autor:
Ekram Makary, R. Bruce Montgomery, Michael Bonham, Jonathan E. Grim, Peter S. Nelson, William L. Stahl, Robert L. Vessella
Publikováno v:
The Prostate. 65:141-150
BACKGROUND. The present study was designed to determine if estrogens change microtubule polymerization and modulate cell cycle progression in vitro, related to modulation of tubulin expression and to determine if estrogens had antagonistic or synergi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4d1c5c09a9d0fd25d2810803fd19c49
https://doi.org/10.1002/pros.20246
https://doi.org/10.1002/pros.20246
Autor:
Jonathan E. Grim
Publikováno v:
Gut. 63:707-709
The recent explosion in cancer genomics provides an unprecedented view of the genetic changes present in solid tumours. The characterisation of colorectal cancer samples via DNA sequencing has confirmed the importance of established oncogene and tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93ebf7aab3f2699f38d5792062a76529
https://doi.org/10.1136/gutjnl-2013-305144
https://doi.org/10.1136/gutjnl-2013-305144
Autor:
Bruce E. Clurman, Jonathan E. Grim
Publikováno v:
Trends in Cell Biology. 13:396-399
Cyclin-dependent kinase 2 (CDK2) regulates diverse aspects of the mammalian cell cycle. Most cancer cells contain mutations in the pathways that control CDK2, and CDK2 activity has received much attention as a target for cancer therapy. However, a re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca023fbb20b89577c293d6752c492f86
https://doi.org/10.1016/s0962-8924(03)00148-x
https://doi.org/10.1016/s0962-8924(03)00148-x