Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Jonathan E. Friedman"'
Autor:
Ofer Firstenberg, Yakov Solomons, Slava Smartsev, Nir Davidson, David Eger, Jonathan E. Friedman, Chitram Banerjee
Publikováno v:
Optics letters. 45(13)
The Fresnel-Fizeau effect of transverse drag, in which the trajectory of a light beam changes due to the transverse motion of the optical medium, is usually extremely small and hard to detect. We observe transverse drag in a moving hot-vapor cell, ut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2513929721c97a064d7783da0337505
https://pubmed.ncbi.nlm.nih.gov/32630863
https://pubmed.ncbi.nlm.nih.gov/32630863
Autor:
Osama A. Alsaied, Noel Y. Calingasan, Jonathan E. Friedman, M. Flint Beal, Mahmoud Kiaei, Juan C. Chavez, Elizabeth Wille, Susanne Petri, Oxana Baranova
Publikováno v:
Journal of Neurochemistry. 102:991-1000
One of the hypotheses for the development of familial amyotrophic lateral sclerosis (ALS) is that mutations in the superoxide dismutase 1 enzyme lead to aberrant properties of the copper within the active site of the enzyme which then causes increase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bdb4f69d9ab336b3d94922de3f6ce93d
https://doi.org/10.1111/j.1471-4159.2007.04604.x
https://doi.org/10.1111/j.1471-4159.2007.04604.x
Autor:
Joo-Yong Lee, Israel Shapiro, Jonathan E. Friedman, Firas M. Younis, Gilad Rosenberg, Arik Dahan, Revital Duvdevani, Eran Dvir, Amnon Hoffman, Shaul Raz, Itzchak Angel, Jae-Young Koh, Alex Kozak
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 318:1248-1256
Indomethacin has been suggested for the treatment of Alzheimer's disease (AD), but its use is limited by gastrointestinal and renal toxicity. To overcome this limitation, D-Pharm Ltd. (Rehovot, Israel) developed DP-155 (mixture of 1-steroyl and 1-pal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d15e08df3dbaac9f1508ce4ead7a983a
https://doi.org/10.1124/jpet.106.103184
https://doi.org/10.1124/jpet.106.103184
Autor:
Olga V. Nikolskaia, Elizabeth Nenortas, Jonathan E. Friedman, Theresa A. Shapiro, Dennis J. Grab, Rahul P. Bakshi
Publikováno v:
Parasitology International. 62(5):461-463
Malaria (Plasmodium spp.) and human African trypanosomiasis (Trypanosoma brucei spp.) are vector borne, deadly parasitic diseases. While chemotherapeutic agents for both diseases are available, difficulty in disease eradication and development of dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a984092cf935bfc083fca8f41af58a8b
Publikováno v:
Neurobiology of Aging. 25:1315-1321
Metals such as zinc, copper and iron contribute to aggregation of amyloid-beta (Abeta) protein and deposition of amyloid plaques in Alzheimer's disease (AD). We examined whether the lipophilic metal chelator DP-109 inhibited these events in aged fema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d8c7fc7dfa25e28d2482e3d47171cb9
https://doi.org/10.1016/j.neurobiolaging.2004.01.005
https://doi.org/10.1016/j.neurobiolaging.2004.01.005
Publikováno v:
Journal of Biological Chemistry. 277:34295-34302
Neurotrophins support neuronal survival and differentiation via Trk receptors, yet can also induce cell death via the p75 receptor. In these studies, we investigated signaling mechanisms governing p75-mediated death of hippocampal neurons, specifical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35dadc0ea717de739d495fa684ca0927
https://doi.org/10.1074/jbc.m205167200
https://doi.org/10.1074/jbc.m205167200
Autor:
Sarina Striem, Alex Kozak, Adina Bar, Galia Taler, Tammy Horovitz, Gilad Rosenberg, Dalia Resnitsky, Jonathan E. Friedman, Michael Krakovsky, Itzchak Angel
Publikováno v:
Drug Development Research. 56:300-309
Disturbance in metallochemical reactions and metal-protein association are associated with chronic neurodegenerative conditions, such as Alzheimer's and Parkinson's disease, as well as with neurodegeneration triggered by acute cerebral ischaemia. Man
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fb86a53616910cefa81bb1e3a8f72ad
https://doi.org/10.1002/ddr.10083
https://doi.org/10.1002/ddr.10083
Publikováno v:
Experimental Neurology. 146:403-413
An important cause of anoxia-induced nerve injury involves the disruption of the ionic balance that exists across the neuronal membrane. This loss of ionic homeostasis results in an increase in intracellular calcium, sodium, and hydrogen and is corre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8b5ed0f27651a98864072fea12dd267
https://doi.org/10.1006/exnr.1997.6544
https://doi.org/10.1006/exnr.1997.6544
Publikováno v:
Developmental Brain Research. 97:194-206
Although it is well documented that glutamate receptor subtypes are differentially expressed during central nervous system development postnatally, how glutamate affects neurons during postnatal development is unclear. We therefore examined the devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61c640519468c9a0fac3fcf8ce51d61c
https://doi.org/10.1016/s0165-3806(96)00149-6
https://doi.org/10.1016/s0165-3806(96)00149-6
Publikováno v:
European journal of pharmacology. 618(1-3)
Zinc plays a key pathophysiological role in major neurological disorders as well as diabetes, while being essential for the activity of numerous zinc binding proteins. A major challenge in chelation based therapy must take into consideration these ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fca8ab7b1e279b8b7e24ca5db9f8d805
https://pubmed.ncbi.nlm.nih.gov/19622352
https://pubmed.ncbi.nlm.nih.gov/19622352