Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Jonathan E Schulz"'
Autor:
Julia R. Port, Claude Kwe Yinda, Jade C. Riopelle, Zachary A. Weishampel, Taylor A. Saturday, Victoria A. Avanzato, Jonathan E. Schulz, Myndi G. Holbrook, Kent Barbian, Rose Perry-Gottschalk, Elaine Haddock, Craig Martens, Carl. I. Shaia, Teresa Lambe, Sarah C. Gilbert, Neeltje van Doremalen, Vincent J. Munster
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Limited data is available on the effect of vaccination and previous virus exposure on the nature of SARS-CoV-2 transmission and immune-pressure on variants. To understand the impact of pre-existing immunity on SARS-CoV-2 airborne transmissio
Externí odkaz:
https://doaj.org/article/c78035e118024b6da19f983dc2509044
Autor:
Claude Kwe Yinda, Dylan H. Morris, Robert J. Fischer, Shane Gallogly, Zachary A. Weishampel, Julia R. Port, Trenton Bushmaker, Jonathan E. Schulz, Kyle Bibby, Neeltje van Doremalen, James O. Lloyd-Smith, Vincent J. Munster
Publikováno v:
Emerging Infectious Diseases, Vol 29, Iss 10, Pp 2065-2072 (2023)
An outbreak of human mpox infection in nonendemic countries appears to have been driven largely by transmission through body fluids or skin-to-skin contact during sexual activity. We evaluated the stability of monkeypox virus (MPXV) in different envi
Externí odkaz:
https://doaj.org/article/ee384dabd960462e8b5506cb79a5019e
Autor:
Julia R Port, Dylan H Morris, Jade C Riopelle, Claude Kwe Yinda, Victoria A Avanzato, Myndi G Holbrook, Trenton Bushmaker, Jonathan E Schulz, Taylor A Saturday, Kent Barbian, Colin A Russell, Rose Perry-Gottschalk, Carl Shaia, Craig Martens, James O Lloyd-Smith, Robert J Fischer, Vincent J Munster
Publikováno v:
eLife, Vol 12 (2024)
It remains poorly understood how SARS-CoV-2 infection influences the physiological host factors important for aerosol transmission. We assessed breathing pattern, exhaled droplets, and infectious virus after infection with Alpha and Delta variants of
Externí odkaz:
https://doaj.org/article/4c84307fc85040989316830046220c70
Autor:
Neeltje van Doremalen, Victoria A. Avanzato, Kerry Goldin, Friederike Feldmann, Jonathan E. Schulz, Elaine Haddock, Atsushi Okumura, Jamie Lovaglio, Patrick W. Hanley, Kathleen Cordova, Greg Saturday, Emmie de Wit, Teresa Lambe, Sarah C. Gilbert, Vincent J. Munster
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-8 (2022)
Abstract Nipah virus (NiV) is a highly pathogenic and re-emerging virus, which causes sporadic but severe infections in humans. Currently, no vaccines against NiV have been approved. We previously showed that ChAdOx1 NiV provides full protection agai
Externí odkaz:
https://doaj.org/article/83a42009c7d8459eafa1e723eb0e5001
Autor:
Neeltje van Doremalen, Jonathan E. Schulz, Danielle R. Adney, Taylor A. Saturday, Robert J. Fischer, Claude Kwe Yinda, Nazia Thakur, Joseph Newman, Marta Ulaszewska, Sandra Belij-Rammerstorfer, Greg Saturday, Alexandra J. Spencer, Dalan Bailey, Colin A. Russell, Sarah C. Gilbert, Teresa Lambe, Vincent J. Munster
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Whilst the ChAdOx1 nCoV-19 (AZD1222) vaccine has demonstrated efficacy against symptomatic disease, variants of concern (VOCs) with spike protein substitutions have led researchers to explore updating vaccines from ancestral spike protein. Authors us
Externí odkaz:
https://doaj.org/article/31185d37259445658dbebb616238f453
Novel Hendra Virus Variant Circulating in Black Flying Foxes and Grey-Headed Flying Foxes, Australia
Autor:
Alison J. Peel, Claude Kwe Yinda, Edward J. Annand, Adrienne S. Dale, Peggy Eby, John-Sebastian Eden, Devin N. Jones, Maureen K. Kessler, Tamika J. Lunn, Tim Pearson, Jonathan E. Schulz, Ina L. Smith, Vincent J. Munster, Raina K. Plowright
Publikováno v:
Emerging Infectious Diseases, Vol 28, Iss 5, Pp 1043-1047 (2022)
A novel Hendra virus variant, genotype 2, was recently discovered in a horse that died after acute illness and in Pteropus flying fox tissues in Australia. We detected the variant in flying fox urine, the pathway relevant for spillover, supporting an
Externí odkaz:
https://doaj.org/article/fd89944b0eec44e6966cc7c0c704908e
Autor:
Robert J. Fischer, Neeltje van Doremalen, Danielle R. Adney, Claude Kwe Yinda, Julia R. Port, Myndi G. Holbrook, Jonathan E. Schulz, Brandi N. Williamson, Tina Thomas, Kent Barbian, Sarah L. Anzick, Stacy Ricklefs, Brian J. Smith, Dan Long, Craig Martens, Greg Saturday, Emmie de Wit, Sarah C. Gilbert, Teresa Lambe, Vincent J. Munster
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Emerging SARS-CoV-2 variants raise concerns about vaccine effectiveness. Here, the authors show that the ChAdOx1 nCoV-19 (AZD1222) vaccine protects Syrian hamsters from pulmonary infection and disease after infection with SARS-CoV-2 B.1.351 or B.1.1.
Externí odkaz:
https://doaj.org/article/cd521c32186f4059b6298768dcc0d51a
Autor:
Danielle R. Adney, Jamie Lovaglio, Jonathan E. Schulz, Claude Kwe Yinda, Victoria A. Avanzato, Elaine Haddock, Julia R. Port, Myndi G. Holbrook, Patrick W. Hanley, Greg Saturday, Dana Scott, Carl Shaia, Andrew M. Nelson, Jessica R. Spengler, Cassandra Tansey, Caitlin M. Cossaboom, Natalie M. Wendling, Craig Martens, John Easley, Seng Wai Yap, Stephanie N. Seifert, Vincent J. Munster
Publikováno v:
JCI Insight, Vol 7, Iss 22 (2022)
An animal model that fully recapitulates severe COVID-19 presentation in humans has been a top priority since the discovery of SARS-CoV-2 in 2019. Although multiple animal models are available for mild to moderate clinical disease, models that develo
Externí odkaz:
https://doaj.org/article/031af6abe49245eab4d9857ca6bed35e
Autor:
Julia R. Port, Claude Kwe Yinda, Irene Offei Owusu, Myndi Holbrook, Robert Fischer, Trenton Bushmaker, Victoria A. Avanzato, Jonathan E. Schulz, Craig Martens, Neeltje van Doremalen, Chad S. Clancy, Vincent J. Munster
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Here, Port and Yinda et al. directly compare the relative contribution of contact, fomite, and airborne transmission route of SARS-CoV-2 to disease outcome in Syrian hamsters; while intranasal and aerosol inoculation causes severe pathogenesis, fomit
Externí odkaz:
https://doaj.org/article/4a4ae0743895463b83727995473e62dd
Autor:
Stephanie N Seifert, Robert J Fischer, Eeva Kuisma, Cynthia Badzi Nkoua, Gerard Bounga, Marc-Joël Akongo, Jonathan E Schulz, Beatriz Escudero-Pérez, Beal-Junior Akoundzie, Vishnou Reize Bani Ampiri, Ankara Dieudonne, Ghislain Dzeret Indolo, Serge D Kaba, Igor Louzolo, Lucette Nathalie Macosso, Yanne Mavoungou, Valchy Bel-Bebi Miegakanda, Rock Aimé Nina, Kevin Tolovou Samabide, Alain I Ondzie, Francine Ntoumi, César Muñoz-Fontela, Jean-Vivien Mombouli, Sarah H Olson, Chris Walzer, Fabien Roch Niama, Vincent J Munster
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 6, p e0010504 (2022)
On the 8th of May, 2018, an outbreak of Ebola virus disease (EVD) was declared, originating in the Bikoro region of the Democratic Republic of the Congo (DRC) near the border with neighboring Republic of the Congo (ROC). Frequent trade and migration
Externí odkaz:
https://doaj.org/article/f6fac52858184ab4912b1f275ac026f6