Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jonathan D. Driscoll"'
Autor:
Jonathan D. Driscoll, Philbert S. Tsai, Per Magne Knutsen, Andy Y. Shih, David Kleinfeld, Pablo Blinder, Dimitrios Davalos, Katerina Akassoglou, Patrick J. Drew
Publikováno v:
Nature Methods. 7:981-984
We present a method to form an optical window in the mouse skull that spans millimeters and is stable for months without causing brain inflammation. This enabled us to repeatedly image blood flow in cortical capillaries of awake mice and determine lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39149df4abfc667effa0c98e63c8641a
https://doi.org/10.1038/nmeth.1530
https://doi.org/10.1038/nmeth.1530
Autor:
Ilya Valmianski, Yoav Freund, Jonathan D. Driscoll, David Kleinfeld, David W. Matthews, Andy Y. Shih
Publikováno v:
Journal of Neurophysiology. 104:1803-1811
The on-line identification of labeled cells and vessels is a rate-limiting step in scanning microscopy. We use supervised learning to formulate an algorithm that rapidly and automatically tags fluorescently labeled somata in full-field images of cort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74b9a18a07bb4ac3565a0faaa1a54594
https://doi.org/10.1152/jn.00484.2010
https://doi.org/10.1152/jn.00484.2010
Publikováno v:
Neuromethods ISBN: 9781627037846
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27c252ac6d52d9a63c8e4df02708f906
https://doi.org/10.1007/978-1-62703-785-3_16
https://doi.org/10.1007/978-1-62703-785-3_16
Autor:
Jeffrey J. Field, Gert Cauwenberghs, Jonathan D. Driscoll, Jeff Squier, David Kleinfeld, Satish Iyengar, G. Allen White, Andy Y. Shih
We present a high-speed photon counter for use with two-photon microscopy. Counting pulses of photocurrent, as opposed to analog integration, maximizes the signal-to-noise ratio so long as the uncertainty in the count does not exceed the gain-noise o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::261d339adb25009baf0d0ed6f6139917
https://europepmc.org/articles/PMC3118755/
https://europepmc.org/articles/PMC3118755/
Autor:
Jonathan D. Driscoll, Arnaud Muller, Patrick J. Drew, Pablo Blinder, David Kleinfeld, Philbert S. Tsai, Andy Y. Shih
Publikováno v:
Frontiers in Neuroenergetics
The neurovascular system may be viewed as a distributed nervous system within the brain. It transforms local neuronal activity into a change in the tone of smooth muscle that lines the walls of arterioles and microvessels. We review the current state
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::582f9c90ecf4ced4b66f3142c3f87894
https://doi.org/10.3389/fnene.2011.00001
https://doi.org/10.3389/fnene.2011.00001
Autor:
Patrick J. Drew, John Patrick Kaufhold, David Kleinfeld, Ilya Valmianski, Diana Jeong, Pablo Blinder, Philbert S. Tsai, Jonathan D. Driscoll, Andy Y. Shih
Publikováno v:
SPIE Proceedings.
Blood is a limited resource that supplies neurons and glia with nutriments. How is blood distributed both in a fail-safe way and in response to changing metabolic loads? We examine this issue in rodent cortex. First, in terms of topology, all-optical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25ce8c454faf5bb1f8bf52aa7983018c
https://doi.org/10.1117/12.829588
https://doi.org/10.1117/12.829588
Publikováno v:
Cold Spring Harbor Protocols. 2013:pdb.prot076513
Cerebral blood flow plays a central role in maintaining homeostasis in the brain, and its dysfunction leads to pathological conditions such as stroke. Moreover, understanding the dynamics of blood flow is central to the interpretation of data from im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64ea0c2b69b951db093772c7d22edd21
https://doi.org/10.1101/pdb.prot076513
https://doi.org/10.1101/pdb.prot076513
Autor:
Chris B. Schaffer, Patrick J. Drew, David Kleinfeld, Nozomi Nishimura, Andy Y. Shih, Jonathan D. Driscoll
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 33:319-319
The cerebral vascular system services the constant demand for energy during neuronal activity in the brain. Attempts to delineate the logic of neurovascular coupling have been greatly aided by the advent of two-photon laser scanning microscopy to ima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfad61f7691c846a7258563e46f84f9b
https://doi.org/10.1038/jcbfm.2012.177
https://doi.org/10.1038/jcbfm.2012.177