Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jonathan D Vaught"'
Autor:
Noh Jin Park, Xiuqiang Wang, Angelica Diaz, Dana M Goos-Root, Christopher Bock, Jonathan D Vaught, Weimin Sun, Charles M Strom
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71703 (2013)
Response to cetuximab (Erbitux®) and panitumumab (Vectibix®) varies among individuals, and even those who show response ultimately gain drug resistance. One possible etiologic factor is differential interaction between the drug and target. We descr
Externí odkaz:
https://doaj.org/article/4c9c2c7cf22b46339e33ca84db5583ea
Autor:
Stephan Kraemer, Jonathan D Vaught, Christopher Bock, Larry Gold, Evaldas Katilius, Tracy R Keeney, Nancy Kim, Nicholas A Saccomano, Sheri K Wilcox, Dom Zichi, Glenn M Sanders
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26332 (2011)
Recently, we reported a SOMAmer-based, highly multiplexed assay for the purpose of biomarker identification. To enable seamless transition from highly multiplexed biomarker discovery assays to a format suitable and convenient for diagnostic and life-
Externí odkaz:
https://doaj.org/article/660cbe7bdb6749a2a78713066bc2e12b
Autor:
Larry Gold, Deborah Ayers, Jennifer Bertino, Christopher Bock, Ashley Bock, Edward N Brody, Jeff Carter, Andrew B Dalby, Bruce E Eaton, Tim Fitzwater, Dylan Flather, Ashley Forbes, Trudi Foreman, Cate Fowler, Bharat Gawande, Meredith Goss, Magda Gunn, Shashi Gupta, Dennis Halladay, Jim Heil, Joe Heilig, Brian Hicke, Gregory Husar, Nebojsa Janjic, Thale Jarvis, Susan Jennings, Evaldas Katilius, Tracy R Keeney, Nancy Kim, Tad H Koch, Stephan Kraemer, Luke Kroiss, Ngan Le, Daniel Levine, Wes Lindsey, Bridget Lollo, Wes Mayfield, Mike Mehan, Robert Mehler, Sally K Nelson, Michele Nelson, Dan Nieuwlandt, Malti Nikrad, Urs Ochsner, Rachel M Ostroff, Matt Otis, Thomas Parker, Steve Pietrasiewicz, Daniel I Resnicow, John Rohloff, Glenn Sanders, Sarah Sattin, Daniel Schneider, Britta Singer, Martin Stanton, Alana Sterkel, Alex Stewart, Suzanne Stratford, Jonathan D Vaught, Mike Vrkljan, Jeffrey J Walker, Mike Watrobka, Sheela Waugh, Allison Weiss, Sheri K Wilcox, Alexey Wolfson, Steven K Wolk, Chi Zhang, Dom Zichi
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15004 (2010)
The interrogation of proteomes ("proteomics") in a highly multiplexed and efficient manner remains a coveted and challenging goal in biology and medicine.We present a new aptamer-based proteomic technology for biomarker discovery capable of simultane
Externí odkaz:
https://doaj.org/article/60cf7be12d92486ea0f48de33701edfa
Autor:
Stephan Kraemer, Christopher Bock, Jonathan D. Vaught, Bridget Lollo, Alex Stewart, Martin Stanton, Malti Nikrad, Jeffrey J. Walker, Larry Gold, Tracy R. Keeney
Publikováno v:
JALA: Journal of the Association for Laboratory Automation. 14:360-366
At SomaLogic, we have embarked on an ambitious program of clinical studies using a novel aptamerbased proteomics technology to discover biomarkers and develop new tools to diagnose, understand, and treat human disease. As part of this program, we des
Publikováno v:
The Journal of Physical Chemistry B. 109:5927-5934
In this work nine DNA hairpins (HPs) are studied at room temperature to observe their pyrene(*+)/dU(*-) CT excited-state dynamics following photoexcitation at 355 nm with a 25 ps laser pulse. The HPs are 18-24 bases long, have a central tetra-T loop,
Publikováno v:
Journal of the American Chemical Society. 126:11231-11237
Seven UTP derivatives modified at the 5-position through an amide linkage were tested as substrates for T7 RNA polymerase (T7 RNAP) transcription. All UTP derivatives gave good yields of full-length transcript even from DNA templates that showed a si
Autor:
Jonathan D. Vaught, Xiuqiang Wang, Charles M. Strom, Noh Jin Park, Christopher Bock, Weimin Sun, Angelica Diaz, Dana M. Goos-Root
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71703 (2013)
PLoS ONE
PLoS ONE
Background Response to cetuximab (Erbitux®) and panitumumab (Vectibix®) varies among individuals, and even those who show response ultimately gain drug resistance. One possible etiologic factor is differential interaction between the drug and targe
Autor:
John C. Rohloff, Susan Jennings, Stephan Kraemer, Edward N. Brody, Mike Mehan, Evaldas Katilius, Jeffrey J. Walker, Ashley Bock, Shashi Kumar Gupta, Robert Mehler, Jeffrey D. Carter, Sally K. Nelson, Michele Nelson, Cate Fowler, Mike Watrobka, Bruce E. Eaton, Nebojsa Janjic, Thale C. Jarvis, Daniel Schneider, Suzanne Stratford, Ngan Le, Dennis Halladay, Deborah Ayers, Bridget Lollo, Sheri K. Wilcox, Glenn Sanders, Christopher Bock, Daniel I. Resnicow, Allison Weiss, Trudi Foreman, Sheela Waugh, Virginia Cunningham, Matt Otis, Tim Fitzwater, Martin Stanton, Tracy R. Keeney, Joe Heilig, Tad H. Koch, Gregory M. Husar, Larry Gold, Alex Stewart, Urs A. Ochsner, Nancy Kim, Britta Singer, Jennifer Bertino, Wes Mayfield, Daniel M. Levine, Mike Vrkljan, Meredith Goss, Malti Nikrad, Ashley Forbes, Jonathan D. Vaught, Thomas S. Parker, Luke Kroiss, Sarah Sattin, Dom Zichi, Alana Sterkel, Wes Lindsey, Alexey D. Wolfson, Steve Pietrasiewicz, Steve Wolk, Andrew B. Dalby, Brian Hicke, Rachel Ostroff, Jim Heil, Dylan Flather, Terese Kaske, Dan Nieuwlandt, Bharat Gawande, Chi Zhang, Magda Gunn
Publikováno v:
Nature Precedings
Interrogation of the human proteome in a highly multiplexed and efficient manner remains a coveted and challenging goal in biology. We present a new aptamer-based proteomic technology for biomarker discovery capable of simultaneously measuring thousa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edba1f85bc2044e505d070fd97874ae7
http://hdl.handle.net/10101/npre.2010.4538.1
http://hdl.handle.net/10101/npre.2010.4538.1
Autor:
Matt Otis, Chris Bock, Sheela Waugh, Sheri K. Wilcox, Jonathan D. Vaught, Justin C. Rolando, Daniel J. Schneider, Tim Fitzwater, Jeffrey D. Carter, Bruce E. Eaton
Publikováno v:
Journal of the American Chemical Society. 132(12)
Six new 5-position modified dUTP derivatives connected by a unique amide linkage were synthesized and tested for compatibility with the enzymatic steps of in vitro selection. Six commercially available DNA polymerases were tested for their ability to
Autor:
Jonathan D Vaught, Bruce E. Eaton
Publikováno v:
Journal of the American Chemical Society. 127:6911-6912