Zobrazeno 1 - 10
of 245
pro vyhledávání: '"Jonathan D Schertzer"'
Autor:
Rodrigo Rodrigues e-Lacerda, Han Fang, Nazli Robin, Arshpreet Bhatwa, Daniel M. Marko, Jonathan D. Schertzer
Publikováno v:
Biomedical Journal, Vol 46, Iss 5, Pp 100610- (2023)
Gut microbiota influence host immunity and metabolism during obesity. Bacterial sensors of the innate immune system relay signals from specific bacterial components (i.e., postbiotics) that can have opposing outcomes on host metabolic inflammation. N
Externí odkaz:
https://doaj.org/article/6426ea61ae034648a7266ef3b63f8eb2
Autor:
Yun Han Kwon, Suhrid Banskota, Huaqing Wang, Laura Rossi, Jensine A. Grondin, Saad A. Syed, Yeganeh Yousefi, Jonathan D. Schertzer, Katherine M. Morrison, Michael G. Wade, Alison C. Holloway, Michael G. Surette, Gregory R. Steinberg, Waliul I. Khan
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Abstract Chemicals in food are widely used leading to significant human exposure. Allura Red AC (AR) is a highly common synthetic colorant; however, little is known about its impact on colitis. Here, we show chronic exposure of AR at a dose found in
Externí odkaz:
https://doaj.org/article/e22bc7fbc4f04c989edfbdc65e3e4ed2
Publikováno v:
Physiological Reports, Vol 10, Iss 16, Pp n/a-n/a (2022)
Abstract Postbiotics are microbial‐derived components or metabolites that can influence host immunity and metabolism. Some postbiotics can improve blood glucose control and lower inflammation during bacterial or nutritional stress. Bacterial cell w
Externí odkaz:
https://doaj.org/article/7c95a977a95a45659fafb34318c4c4fa
Autor:
Lindsay A. Broadfield, Amna Saigal, Jake C. Szamosi, Joanne A. Hammill, Ksenia Bezverbnaya, Dongdong Wang, Jaya Gautam, Evangelia E. Tsakiridis, Fiorella Di Pastena, Jamie McNicol, Jianhan Wu, Saad Syed, James S.V. Lally, Amogelang R. Raphenya, Marie-Jose Blouin, Michael Pollak, Andrea Sacconi, Giovanni Blandino, Andrew G. McArthur, Jonathan D. Schertzer, Michael G. Surette, Stephen M. Collins, Jonathan L. Bramson, Paola Muti, Theodoros Tsakiridis, Gregory R. Steinberg
Publikováno v:
Molecular Metabolism, Vol 61, Iss , Pp 101498- (2022)
Background/Purpose: Type 2 diabetes and obesity increase the risk of developing colorectal cancer. Metformin may reduce colorectal cancer but the mechanisms mediating this effect remain unclear. In mice and humans, a high-fat diet (HFD), obesity and
Externí odkaz:
https://doaj.org/article/9fae3275a0774580a7ba65a044f50126
Autor:
Yun Han Kwon, Suhrid Banskota, Huaqing Wang, Laura Rossi, Jensine A. Grondin, Saad A. Syed, Yeganeh Yousefi, Jonathan D. Schertzer, Katherine M. Morrison, Michael G. Wade, Alison C. Holloway, Michael G. Surette, Gregory R. Steinberg, Waliul I. Khan
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/980b7271ae484db98ed373f034b78d87
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101098- (2022)
Summary: Postbiotics cooperate to influence immune and metabolic outcomes in the host. Here we describe a protocol for in vivo assessment of blood glucose control following acute administration of lipopolysaccharide (LPS) and peptidoglycan (PGN) in m
Externí odkaz:
https://doaj.org/article/414079bc845d4947a8a8cb98fafbf43d
Autor:
Fernando F. Anhê, Soumaya Zlitni, Nicole G. Barra, Kevin P. Foley, Mats I. Nilsson, Joshua P. Nederveen, Lauren G. Koch, Steven L. Britton, Mark A. Tarnopolsky, Jonathan D. Schertzer
Publikováno v:
Physiological Reports, Vol 10, Iss 5, Pp n/a-n/a (2022)
Abstract High aerobic endurance capacity can be acquired by training and/or inherited. Aerobic exercise training (AET) and aging are linked to altered gut microbiome composition, but it is unknown if the environmental stress of exercise and host gene
Externí odkaz:
https://doaj.org/article/d6b7b4c6e9f640569de57fe79f1af509
Autor:
Brittany M. Duggan, Akhilesh K. Tamrakar, Nicole G. Barra, Fernando F. Anhê, Gabriella Paniccia, Jessica G. Wallace, Hannah D. Stacey, Michael G. Surette, Matthew S. Miller, Deborah M. Sloboda, Jonathan D. Schertzer
Publikováno v:
Molecular Metabolism, Vol 55, Iss , Pp 101404- (2022)
Objective: Obesity and diabetes increase circulating levels of microbial components derived from the gut microbiota. Individual bacterial factors (i.e., postbiotics) can have opposing effects on blood glucose. Methods: We tested the net effect of gut
Externí odkaz:
https://doaj.org/article/0ecfcb494020486c9c9f21ee6d28b730
Autor:
Fernando F. Anhê, Nicole G. Barra, Joseph F. Cavallari, Brandyn D. Henriksbo, Jonathan D. Schertzer
Publikováno v:
Cell Reports, Vol 36, Iss 11, Pp 109691- (2021)
Summary: Lipopolysaccharides (LPSs) can promote metabolic endotoxemia, which is considered inflammatory and metabolically detrimental based on Toll-like receptor (TLR)4 agonists, such as Escherichia coli-derived LPS. LPSs from certain bacteria antago
Externí odkaz:
https://doaj.org/article/8232242716ab450f8f3e31a20afcd027
Autor:
Basma A. Ahmed, Frank J. Ong, Nicole G. Barra, Denis P. Blondin, Elizabeth Gunn, Stephan M. Oreskovich, Jake C. Szamosi, Saad A. Syed, Emily K. Hutchings, Norman B. Konyer, Nina P. Singh, Julian M. Yabut, Eric M. Desjardins, Fernando F. Anhê, Kevin P. Foley, Alison C. Holloway, Michael D. Noseworthy, Francois Haman, Andre C. Carpentier, Michael G. Surette, Jonathan D. Schertzer, Zubin Punthakee, Gregory R. Steinberg, Katherine M. Morrison
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 9, Pp 100397- (2021)
Summary: In rodents, lower brown adipose tissue (BAT) activity is associated with greater liver steatosis and changes in the gut microbiome. However, little is known about these relationships in humans. In adults (n = 60), we assessed hepatic fat and
Externí odkaz:
https://doaj.org/article/3f605dad37834d20b7e3330887e81098