Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Jonathan D Hibshman"'
Publikováno v:
PLoS Genetics, Vol 14, Iss 8, p e1007639 (2018)
[This corrects the article DOI: 10.1371/journal.pgen.1006396.].
Externí odkaz:
https://doaj.org/article/50554b6e286c4d7c89774c503d9e6028
Autor:
Jonathan D Hibshman, Alexander E Doan, Brad T Moore, Rebecca EW Kaplan, Anthony Hung, Amy K Webster, Dhaval P Bhatt, Rojin Chitrakar, Matthew D Hirschey, L Ryan Baugh
Publikováno v:
eLife, Vol 6 (2017)
daf-16/FoxO is required to survive starvation in Caenorhabditis elegans, but how daf-16IFoxO promotes starvation resistance is unclear. We show that daf-16/FoxO restructures carbohydrate metabolism by driving carbon flux through the glyoxylate shunt
Externí odkaz:
https://doaj.org/article/df555101367d4886892c0763af81b7f2
Publikováno v:
Cell Reports, Vol 43, Iss 11, Pp 114956- (2024)
Summary: Desiccation kills most cells. Some proteins have been identified to help certain cells survive desiccation, but many protein protectants are likely to be unknown. Moreover, the mechanisms ensuring protection of key cellular components are in
Externí odkaz:
https://doaj.org/article/d99dc21ff2604b0c9a702f931135c0ac
Publikováno v:
PLoS Genetics, Vol 12, Iss 10, p e1006396 (2016)
Maternal effects of environmental conditions produce intergenerational phenotypic plasticity. Adaptive value of these effects depends on appropriate anticipation of environmental conditions in the next generation, and mismatch between conditions may
Externí odkaz:
https://doaj.org/article/25ec56ce811f401d8fd642ad02e9d6b6
Autor:
Clayton J. Harry, Jonathan D. Hibshman, Amor Damatac, II, Phillip L. Davidson, Martin Andres Estermann, Marycruz Flores-Flores, Caroline M. Holmes, Jorge Lázaro, Elizabeth-Ann Legere, Jake Leyhr, Siddharthan Balachandar Thendral, Bridget A. Vincent, Bob Goldstein
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103232- (2024)
Summary: Tardigrades are microscopic organisms with exceptional resilience to environmental extremes. Most protocols to visualize the internal anatomy of tardigrades rely on fixation, hampering our understanding of dynamic changes to organelles and o
Externí odkaz:
https://doaj.org/article/e74dabf59a4e4972a4db68e6cff106fd
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-10 (2023)
Small heat shock proteins from the tardigrade Hypsibius exemplaris are shown to provide a mechanism of stress resistance that can support not just heat tolerance but desiccation tolerance as well.
Externí odkaz:
https://doaj.org/article/2241e60e3ae94eb685f0d6d399502d32
Autor:
Jonathan D. Hibshman, Bob Goldstein
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-22 (2021)
Abstract Background Cells and organisms typically cannot survive in the absence of water. However, some animals including nematodes, tardigrades, rotifers, and some arthropods are able to survive near-complete desiccation. One class of proteins known
Externí odkaz:
https://doaj.org/article/bf8e5e6f1ee8405c920734674eb097e5
Autor:
Amy K. Webster, Anthony Hung, Brad T. Moore, Ryan Guzman, James M. Jordan, Rebecca E. W. Kaplan, Jonathan D. Hibshman, Robyn E. Tanny, Daniel E. Cook, Erik Andersen, L. Ryan Baugh
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 10, Pp 3477-3488 (2019)
To understand the genetic basis of complex traits, it is important to be able to efficiently phenotype many genetically distinct individuals. In the nematode Caenorhabditis elegans, individuals have been isolated from diverse populations around the g
Externí odkaz:
https://doaj.org/article/aedd67b78e1245168d3645e4b5015320
Autor:
Kathleen A. Hershberger, John P. Rooney, Elena A. Turner, Lauren J. Donoghue, Rakesh Bodhicharla, Laura L. Maurer, Ian T. Ryde, Jina J. Kim, Rashmi Joglekar, Jonathan D. Hibshman, Latasha L. Smith, Dhaval P. Bhatt, Olga R. Ilkayeva, Matthew D. Hirschey, Joel N. Meyer
Publikováno v:
Redox Biology, Vol 43, Iss , Pp 102000- (2021)
The consequences of damage to the mitochondrial genome (mtDNA) are poorly understood, although mtDNA is more susceptible to damage resulting from some genotoxicants than nuclear DNA (nucDNA), and many environmental toxicants target the mitochondria.
Externí odkaz:
https://doaj.org/article/b4cfc3d8ec28428e988509c328dc431a
Publikováno v:
STAR Protocols, Vol 2, Iss 1, Pp 100276- (2021)
Summary: Standard laboratory culture of Caenorhabditis elegans utilizes solid growth media with a bacterial food source. However, this culture method limits control of food availability and worm population density, factors that impact many life-histo
Externí odkaz:
https://doaj.org/article/0fba8d0185c544c6a690beb9d4a1d8eb