Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Jonathan D, Edgeworth"'
Autor:
Adela Alcolea-Medina, Christopher Alder, Luke B. Snell, Themoula Charalampous, Alp Aydin, Gaia Nebbia, Tom Williams, Simon Goldenberg, Sam Douthwaite, Rahul Batra, Penelope R. Cliff, Hannah Mischo, Stuart Neil, Mark Wilks, Jonathan D. Edgeworth
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-13 (2024)
Abstract Background Clinical metagenomics involves the genomic sequencing of all microorganisms in clinical samples ideally after depletion of human DNA to increase sensitivity and reduce turnaround times. Current human DNA depletion methods preferen
Externí odkaz:
https://doaj.org/article/f1230e3b9d7043e3b1690633d8aee781
Autor:
Adela Alcolea-Medina, Christopher Alder, Luke B. Snell, Themoula Charalampous, Alp Aydin, Gaia Nebbia, Tom Williams, Simon Goldenberg, Sam Douthwaite, Rahul Batra, Penelope R. Cliff, Hannah Mischo, Stuart Neil, Mark Wilks, Jonathan D. Edgeworth
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/79a537bd9e8f4ad3b39631369efa7260
Autor:
Lara Payne, Adela Alcolea-Medina, Luke B Snell, Christopher Alder, Themoula Charalampous, Jake D Turnbull, Jonathan D Edgeworth, Rahul Batra, John L Klein, Anna L Goodman
Publikováno v:
Clinical Infection in Practice, Vol 21, Iss , Pp 100332- (2024)
Background: We describe a case of a 55-year-old shepherd with history of mycotic aneurysm presenting with a chronic aortic endovascular graft infection caused by Nocardia nova and a newly identified Variovorax sp which we named ‘Variovorax durovern
Externí odkaz:
https://doaj.org/article/6943fbd054e8406ca975d92cbf72017d
Autor:
Wenjuan Wang, Luke B Snell, Davide Ferrari, Anna L Goodman, Nicholas M Price, Charles D Wolfe, Vasa Curcin, Jonathan D Edgeworth, Yanzhong Wang
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-7 (2022)
Abstract Introduction Randomised controlled trials have shown that steroids reduce the risk of dying in patients with severe Coronavirus disease 2019 (COVID-19), whilst many real-world studies have failed to replicate this result. We aim to investiga
Externí odkaz:
https://doaj.org/article/8dda7d566c344eda87fd1ba8ba4e2aa5
Autor:
Themoula Charalampous, Adela Alcolea-Medina, Luke B. Snell, Tom G. S. Williams, Rahul Batra, Christopher Alder, Andrea Telatin, Luigi Camporota, Christopher I. S. Meadows, Duncan Wyncoll, Nicholas A. Barrett, Carolyn J. Hemsley, Lisa Bryan, William Newsholme, Sara E. Boyd, Anna Green, Ula Mahadeva, Amita Patel, Penelope R. Cliff, Andrew J. Page, Justin O’Grady, Jonathan D. Edgeworth
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-16 (2021)
Abstract Background Clinical metagenomics (CMg) has the potential to be translated from a research tool into routine service to improve antimicrobial treatment and infection control decisions. The SARS-CoV-2 pandemic provides added impetus to realise
Externí odkaz:
https://doaj.org/article/3c7a335029394a13877c2e9c82267e9d
Autor:
Clemens Gutmann, Kaloyan Takov, Sean A. Burnap, Bhawana Singh, Hashim Ali, Konstantinos Theofilatos, Ella Reed, Maria Hasman, Adam Nabeebaccus, Matthew Fish, Mark JW. McPhail, Kevin O’Gallagher, Lukas E. Schmidt, Christian Cassel, Marieke Rienks, Xiaoke Yin, Georg Auzinger, Salvatore Napoli, Salma F. Mujib, Francesca Trovato, Barnaby Sanderson, Blair Merrick, Umar Niazi, Mansoor Saqi, Konstantina Dimitrakopoulou, Rafael Fernández-Leiro, Silke Braun, Romy Kronstein-Wiedemann, Katie J. Doores, Jonathan D. Edgeworth, Ajay M. Shah, Stefan R. Bornstein, Torsten Tonn, Adrian C. Hayday, Mauro Giacca, Manu Shankar-Hari, Manuel Mayr
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Here the authors use RT-qPCR and mass spectrometry to analyze longitudinal blood samples from intensive care unit (ICU) COVID-19 patients and controls. They find that viral RNA and pentraxin-3 predict 28-day ICU mortality and that galectin-3-binding
Externí odkaz:
https://doaj.org/article/4473e05193134fe3b894751bffb9a062
Autor:
Ceri Alan Fielding, Pragati Sabberwal, James C Williamson, Edward JD Greenwood, Thomas WM Crozier, Wioleta Zelek, Jeffrey Seow, Carl Graham, Isabella Huettner, Jonathan D Edgeworth, David A Price, Paul B Morgan, Kristin Ladell, Matthias Eberl, Ian R Humphreys, Blair Merrick, Katie Doores, Sam J Wilson, Paul J Lehner, Eddie CY Wang, Richard J Stanton
Publikováno v:
eLife, Vol 11 (2022)
The outcome of infection is dependent on the ability of viruses to manipulate the infected cell to evade immunity, and the ability of the immune response to overcome this evasion. Understanding this process is key to understanding pathogenesis, genet
Externí odkaz:
https://doaj.org/article/dac3657f8bfc48e98d71a0036c060efa
Autor:
Thomas Lechmere, Luke B. Snell, Carl Graham, Jeffrey Seow, Zayed A. Shalim, Themoula Charalampous, Adela Alcolea-Medina, Rahul Batra, Gaia Nebbia, Jonathan D. Edgeworth, Michael H. Malim, Katie J. Doores
Publikováno v:
mBio, Vol 13, Iss 2 (2022)
ABSTRACT Numerous studies have shown that a prior SARS-CoV-2 infection can greatly enhance the antibody response to COVID-19 vaccination, with this so called “hybrid immunity” leading to greater neutralization breadth against SARS-CoV-2 variants
Externí odkaz:
https://doaj.org/article/532af9eb26d2434498e1ed5b78f8f9bd
Publikováno v:
The Lancet Microbe, Vol 2, Iss 11, Pp e570- (2021)
Externí odkaz:
https://doaj.org/article/57d10384d9734efe8f4138ba9d06f108
Autor:
Judith Breuer, Catherine F Houlihan, David Partridge, Gaia Nebbia, Jacqui Prieto, Gee Yen Shin, Oliver Stirrup, Kenneth Laing, Rachel Williams, Helen Wheeler, Paul Randell, Ana da Silva Filipe, Tommy Rampling, Tabassum Khan, James Price, Sharon Glaysher, Scott Elliott, Helen Umpleby, Emanuela Pelosi, Emma Thomson, Cristina Venturini, Anna Riddell, Alison Cox, Andrew C Hayward, Malin Bergström, David Harrington, Charlotte Williams, Tanzina Haque, Dianne Irish, Adrienn Angyal, Marios Margaritis, Florencia Boshier, José Afonso Guerra-Assunção, Adela Alcolea-Medina, Angela Beckett, Themoula Charalampous, Raghavendran Kulasegaran Shylini, Beatrix Kele, Irene Monahan, Guy Mollett, Matthew Parker, Sunando Roy, Joshua Taylor, Sophie Weller, Eleri Wilson-Davies, Phillip Wade, Joseph Hughes, Tabitha Mahungu, Cassie Pope, Samuel Robson, Kordo Saeed, Thushan de Silva, Luke Snell, Adam A Witney, James Blackstone, Leanne Hockey, Georgia Marley, Christine Peters, Flavia Flaviani, Bindi Patel, Tom G S Williams, Rahul Batra, Jonathan D Edgeworth, Pinglawathee Madona, Jennifer Hart, Juanita Pang, Helena Tutill, Nadua Bayzid, Marius Cotic, Luke Green, Benjamin Lindsey, Amy State, Alison Cope, Peijun Zhang, Max Whiteley, Marta Gallis Ramalho, Stella Christou, Stavroula Louka, Hailey Hornsby, Benjamin Foulkes, Paige Wolverson, Joe Heffer, Nikki Smith, Salman Goudarzi, Chris Fearn, Kate Cook, Katie Loveson, Adhyana Mahamana, Buddhini Samaraweera, Siona Silveira, Stephen Aplin, Sarah Jeremiah, Matthew Harvey, Thea Sass, Ngee Keong Tan, Claudia Cardoso Pereira, Dan Frampton, Matt Byott, Judith Heaney, Emilie Sanchez, Stavroula M Paraskevopoulou
Publikováno v:
BMJ Open Respiratory Research, Vol 8, Iss 1 (2021)
Externí odkaz:
https://doaj.org/article/8a895e04928046eab408c7338ade581c