Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jonathan Crain"'
Autor:
Hyae Yon Kweon, Mi-Ni Lee, Max Dorfel, Seungwoon Seo, Leah Gottlieb, Thomas PaPazyan, Nina McTiernan, Rasmus Ree, David Bolton, Andrew Garcia, Michael Flory, Jonathan Crain, Alison Sebold, Scott Lyons, Ahmed Ismail, Elaine Marchi, Seong-keun Sonn, Se-Jin Jeong, Sejin Jeon, Shinyeong Ju, Simon J Conway, Taesoo Kim, Hyun-Seok Kim, Cheolju Lee, Tae-Young Roh, Thomas Arnesen, Ronen Marmorstein, Goo Taeg Oh, Gholson J Lyon
Publikováno v:
eLife, Vol 10 (2021)
Amino-terminal acetylation is catalyzed by a set of N-terminal acetyltransferases (NATs). The NatA complex (including X-linked Naa10 and Naa15) is the major acetyltransferase, with 40–50% of all mammalian proteins being potential substrates. Howeve
Externí odkaz:
https://doaj.org/article/d85446a69857408ca85b40a4aca5a127
Autor:
Ahmed Ismail, Sejin Jeon, Hyun-Seok Kim, Thomas Arnesen, Goo Taeg Oh, Nina McTiernan, Gholson J. Lyon, Se-Jin Jeong, Simon J. Conway, Ronen Marmorstein, Rasmus Ree, David Bolton, Mi-Ni Lee, Michael Flory, Hyae Yon Kweon, Jonathan Crain, Leah Gottlieb, Alison Sebold, Elaine Marchi, Seungwoon Seo, Seong-keun Sonn, TaeSoo Kim, Scott K. Lyons, Cheolju Lee, Tae-Young Roh, Thomas Papazyan, Max Dorfel, Shinyeong Ju, Andrew Garcia
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Amino-terminal acetylation is catalyzed by a set of N-terminal acetyltransferases (NATs). The NatA complex (including X-linked Naa10 and Naa15) is the major acetyltransferase, with 40–50% of all mammalian proteins being potential substrates. Howeve
Autor:
Nina McTiernan, Se-Jin Jeong, Gholson J. Lyon, Tae-Young Roh, Max Dorfel, Alison Sebold, TaeSoo Kim, Thomas Papazyan, Ahmed Ismail, Scott K. Lyons, Elaine Marchi, Goo Taeg Oh, Ronen Marmorstein, Michael Flory, Shinyeong Ju, Jonathan Crain, David Bolton, Hyae Yon Kweon, Seong-keun Sonn, Mi-Ni Lee, Seungwoon Seo, Simon J. Conway, Leah Gottlieb, Rasmus Ree, Sejin Jeon, Hyun-Seok Kim, Thomas Arnesen, Cheolju Lee, Andrew Garcia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c2823c3eb259f0700b9371c3a1ab532
https://doi.org/10.7554/elife.65952.sa2
https://doi.org/10.7554/elife.65952.sa2
Autor:
Gholson J. Lyon, Tae-Young Roh, Rasmus Ree, Elaine Marchi, Shinyeong Ju, Ahmed Ismail, Thomas Papazyan, Jonathan Crain, TaeSoo Kim, Mi-Ni Lee, Andrew Garcia, Max Dorfel, Alison Sebold, Leah Gottlieb, Cheolju Lee, Seungwoon Seo, Goo Taeg Oh, Seong-keun Sonn, Sejin Jeon, Hyun-Seok Kim, Thomas Arnesen, Ronen Marmorstein, Se-Jin Jeong, David Bolton, Hyae Yon Kweon, Michael Flory, Nina McTiernan, Scott K. Lyons, Simon J. Conway
Amino-terminal acetylation is catalyzed by a set of N-terminal acetyltransferases (NATs). The NatA complex (including X-linked Naa10 and Naa15) is the major acetyltransferase, with 40-50% of all mammalian proteins being potential substrates. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f2fc55886786fd05eb1e673dc82ac13
https://doi.org/10.1101/2020.12.19.422860
https://doi.org/10.1101/2020.12.19.422860
Autor:
Yevel Flores-Garcia, Corinne Luedemann, Douglas A. Lauffenburger, Sangeeta N. Bhatia, Ulrike Wille-Reece, Joshua A. Weiner, Erik Jongert, Claudia Arevalo, Galit Alter, Margherita Coccia, Jonathan K. Fallon, Jishnu Das, Jerald C. Sadoff, Thomas Broge, Allison Demas, Margaret E. Ackerman, Sheetij Dutta, Meghan Marquette, Thomas C. Linnekin, Ashlin R. Michell, Jonathan Crain, Matthew D. Slein, Richard Lu, Scott Gregory, Viraj Kulkarni, Jenny Hendriks, Sandra March, Harini Natarajan, Elke S. Bergmann-Leitner, Caitlyn Linde, Todd J. Suscovich, Fidel Zavala
Publikováno v:
Science Translational Medicine. 12
Vaccine development has the potential to be accelerated by coupling tools such as systems immunology analyses and controlled human infection models to define the protective efficacy of prospective immunogens without expensive and slow phase 2b/3 vacc
Publikováno v:
Yeast. 34:19-37
Naa10 is a Nα-terminal acetyltransferase that, in a complex with its auxiliary subunit Naa15, co-translationally acetylates the α-amino group of newly synthetized proteins as they emerge from the ribosome. Roughly 40-50% of the human proteome is ac
Publikováno v:
Yeast (Chichester, England)
Naa10 is an amino-terminal acetyltransferase that, in a complex with its auxiliary subunit Naa15, co-translationally acetylates the amino group of newly synthetized proteins as they emerge from the ribosome. Roughly 40-50% of the human proteome is ac
Autor:
Michael Downes, Yves Boucher, Kamila Naxerova, Ronald M. Evans, Daniel H. Schanne, Jonathan Crain, Cristina R. Ferrone, Rakesh K. Jain, Xialong Qi, Carlos Fernandez-del Castillo, William Ho, Keith D. Lillemoe, Jeffrey W. Clark, David P. Ryan, Jelena Grahovac, Ivy X. Chen, Matthias Pinter, Hadi Tavakoli Nia, Theodore S. Hong, Jessica M. Posada, Hao Liu, Peigen Huang, Vikram Deshpande
Publikováno v:
Cancer Research. 79:A18-A18
The resistance to therapy in pancreatic ductal adenocarcinoma (PDAC) is due in part to carcinoma-associated fibroblasts (CAFs) that produce a highly desmoplastic and proinflammatory tumor microenvironment (TME). Our laboratory has shown that the angi
Autor:
Ronald M. Evans, Andrea Zanconato, Joao Incio, Jonathan Crain, Daniella Dias-Santos, Vikram Deshpande, Carlos Fernandez-del Castillo, Hang Lee, Jeffrey W. Clark, A. Jacobson, Kamila Naxerova, Kohei Shigeta, Janet E. Murphy, James S. Michaelson, David P. Ryan, Keith D. Lillemoe, William Ho, Michael Downes, Yves Boucher, Theodoros Michelakos, Matthias Pinter, Rakesh K. Jain, Cristina R. Ferrone, Hao Liu, Theodore S. Hong
Purpose: Angiotensin system inhibitors (ASI) can improve prognosis in multiple cancer types, including pancreatic ductal adenocarcinoma (PDAC). However, no study has examined the effect of ASIs alone or combined with adjuvant chemotherapy in resected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f1b52b0d114bba455eb3c450029dd4c
https://europepmc.org/articles/PMC5856249/
https://europepmc.org/articles/PMC5856249/
Autor:
Jonathan Crain, Maria Tzetis, Megan Crow, Catherine E. Keegan, Laurence Faivre, Jesse Gillis, Sophia Kitsiou-Tzeli, Sara Ballouz, Max Doerfel, Gholson J. Lyon
SummaryIn characterizing a disease, it is common to search for dysfunctional genes by assaying the transcriptome. The resulting differentially expressed genes are typically assessed for shared features, such as functional annotation or co-expression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2f9c4298ba48c548167e8d99c1bc163