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Genomic regions with high guanine content can fold into non-B form DNA four-stranded structures known as G-quadruplexes (G4s). Extensive in vivo investigations have revealed that promoter G4s are transcriptional regulators. Little structural informat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1cef951746605195afdc792a7a9d2fb
https://doi.org/10.21203/rs.3.rs-1902173/v2
https://doi.org/10.21203/rs.3.rs-1902173/v2
Genomic regions with high guanine content fold into non-B form DNA four-stranded structures known as G-quadruplexes (G4s). Extensive in vivo investigations have revealed that promoter G4s are transcriptional regulators. Little structural information
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4288c753bd345f829929000f1c8284bb
https://doi.org/10.21203/rs.3.rs-1902173/v1
https://doi.org/10.21203/rs.3.rs-1902173/v1
Publikováno v:
Biochimie. 93(8)
Triplex-forming oligonucleotides (TFOs) can bind to the major groove of homopurine-homopyrimidine stretches of double-stranded DNA in a sequence-specific manner through Hoogsteen hydrogen bonding to form DNA triplexes. TFOs by themselves or conjugate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92a4e374f0540d68beee421560b28f01
https://pubmed.ncbi.nlm.nih.gov/21501652
https://pubmed.ncbi.nlm.nih.gov/21501652
Autor:
Jean-Louis Mergny, Jonathan Chaires
Publikováno v:
Biochimie. 90(7)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::375b9d55bd82941911b1ad9331d79511
https://pubmed.ncbi.nlm.nih.gov/18515096
https://pubmed.ncbi.nlm.nih.gov/18515096
Autor:
Donald M. Miller, Alexandra Sokolova, Francine Rezzoug, Shelia Thomas, Jonathan Chaires, William Dean, John Trent
Publikováno v:
Cancer Research. 75:PR02-PR02
Background: Telomerase reverse transcriptase (hTERT) is a catalytic subunit of the enzyme telomerase. It has recently been shown that the hTERT promoter is commonly mutated (>75% of cases) in malignant melanoma. These mutations occur at four sites in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fc5a885a47dcf051f90570f981902b5
https://doi.org/10.1158/1538-7445.mel2014-pr02
https://doi.org/10.1158/1538-7445.mel2014-pr02
Autor:
Jonathan Chaires, Stephen Levene
Publikováno v:
Biopolymers. 103:469-469
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abd1ef8fb16c3d6b4694d917c6b68a5e
https://doi.org/10.1002/bip.22686
https://doi.org/10.1002/bip.22686
Autor:
Jonathan Chaires, Stephen Levene
Publikováno v:
Biopolymers. 103:417-417
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c653aa049e9e8610d574210764c53ae1
https://doi.org/10.1002/bip.22661
https://doi.org/10.1002/bip.22661
Autor:
John Ladbury, Jonathan Chaires
Publikováno v:
Biophysical Chemistry. 126:3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ec6427d5b2a120e680c64791faf46c9
https://doi.org/10.1016/j.bpc.2006.05.032
https://doi.org/10.1016/j.bpc.2006.05.032
Publikováno v:
Scopus-Elsevier
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::094a66efb556ab5fb474db6979172321
http://www.scopus.com/inward/record.url?eid=2-s2.0-0033497816&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0033497816&partnerID=MN8TOARS
Autor:
Mcfail-Isom, L., Coury, J., Holt, L., Conti, T., Preibe, W., Jonathan Chaires, Bottomley, L., Williams, L. D.
Publikováno v:
Scopus-Elsevier
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1e09a39a77a750f9204f07fcc3fb7b23
http://www.scopus.com/inward/record.url?eid=2-s2.0-33645874800&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-33645874800&partnerID=MN8TOARS