Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jonathan Cardoso-Silva"'
Autor:
Pedro Henrique da Costa Avelar, Natalia del Coco, Luis C. Lamb, Sophia Tsoka, Jonathan Cardoso-Silva
Publikováno v:
Healthcare Analytics, Vol 2, Iss , Pp 100115- (2022)
Following the outbreak of the coronavirus epidemic in early 2020, municipalities, regional governments and policymakers worldwide had to plan their Non-Pharmaceutical Interventions (NPIs) amidst a scenario of great uncertainty. At this early stage of
Externí odkaz:
https://doaj.org/article/6112f0027f6845c6a299653ad4da0f41
The discovery of new antimalarial medicines with novel mechanisms of action is important, given the ability of parasites to develop resistance to current treatments. Through the Open Source Malaria project that aims to discover new medications for ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e118562effb4150d430545df1f37a5d
https://doi.org/10.1101/2022.02.12.479469
https://doi.org/10.1101/2022.02.12.479469
Autor:
Pedro Henrique da Costa Avelar, Natalia del Coco, Luis C. Lamb, Sophia Tsoka, Jonathan Cardoso Silva
Publikováno v:
SSRN Electronic Journal.
Autor:
Davy Guan, Alexander Wade, Edwin G Tse, Alice Motion, Willem P. van Hoorn, Jonathan Cardoso-Silva, Adele M. Lehane, Giovanni Cincilla, Mario Öeren, Julia C. R. Lindblom, Mykola Galushka, Murray N. Robertson, Matthew H. Todd, James McCulloch, Slade Matthews, Mark G. Anderson, Benedict Irwin, Thomas M. Whitehead, Paul Willis, Laksh Aithani, Ho Leung Ng, Gareth Conduit, Vasileios A. Tatsis, Vito Spadavecchio, Raymond Lui, Kiaran Kirk, Irene Hallyburton
Publikováno v:
Journal of medicinal chemistry. 64(22)
The discovery of new antimalarial medicines with novel mechanisms of action is key to combating the problem of increasing resistance to our frontline treatments. The Open Source Malaria (OSM) consortium has been developing compounds ("Series 4") that
Background: The novel coronavirus pandemic has affected Brazil's Santa Catarina State (SC) severely. At the time of writing (24 March 2021), over 764,000 cases and over 9,800 deaths by COVID-19 have been confirmed, hospitals were fully occupied with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a369f825280cc19043ae093a98ad8ae
https://doi.org/10.21203/rs.3.rs-444318/v1
https://doi.org/10.21203/rs.3.rs-444318/v1
Publikováno v:
Intelligent Systems ISBN: 9783030916985
Intelligent Systems
Intelligent Systems
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::887cbe78fbb6c108c554019fd005b6e5
https://doi.org/10.1007/978-3-030-91699-2_27
https://doi.org/10.1007/978-3-030-91699-2_27
Publikováno v:
Journal of Computer-Aided Molecular Design
Quantitative Structure-Activity Relationship (QSAR) models are critical in various areas of drug discovery, for example in lead optimisation and virtual screening. Recently, the need for models that are not only predictive but also interpretable has
Publikováno v:
Yang, L, Silva, J C, Papageorgiou, L G & Tsoka, S 2016, ' Community Structure Detection for Directed Networks Through Modularity Optimisation ', Algorithms, vol. 9, no. 4, 73 . https://doi.org/10.3390/a9040073
Algorithms; Volume 9; Issue 4; Pages: 73
Algorithms, Vol 9, Iss 4, p 73 (2016)
Algorithms; Volume 9; Issue 4; Pages: 73
Algorithms, Vol 9, Iss 4, p 73 (2016)
Networks constitute powerful means of representing various types of complex systems, where nodes denote the system entities and edges express the interactions between the entities. An important topological property in complex networks is community st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f15a5b059a03b44076d525c7bf669e0
https://kclpure.kcl.ac.uk/en/publications/7ff2b1e2-65f2-4491-aa86-c30563e567a4
https://kclpure.kcl.ac.uk/en/publications/7ff2b1e2-65f2-4491-aa86-c30563e567a4
Publikováno v:
Silva, J, Bennett, L, Papageorgiou, L G & Tsoka, S 2016, ' A mathematical programming approach for sequential clustering of dynamic networks ', European Physical Journal B, vol. 89, no. 2, 39, pp. 1-10 . https://doi.org/10.1140/epjb/e2015-60656-5
A common analysis performed on dynamic networks is community structure detection, a challenging problem that aims to track the temporal evolution of network modules. An emerging area in this field is evolutionary clustering, where the community struc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::012a676874b97c9bffae158a3a44ad9f
https://kclpure.kcl.ac.uk/ws/files/48920856/art_3A10.1140_2Fepjb_2Fe2015_60656_5.pdf
https://kclpure.kcl.ac.uk/ws/files/48920856/art_3A10.1140_2Fepjb_2Fe2015_60656_5.pdf
Publikováno v:
Cardoso-Silva, J, Papadatos, G, Papageorgiou, L G & Tsoka, S 2018, ' Optimal Piecewise Linear Regression Algorithm for QSAR Modelling ', Molecular Informatics . https://doi.org/10.1002/minf.201800028
Quantitative Structure-Activity Relationship (QSAR) models have been successfully applied to lead optimisation, virtual screening and other areas of drug discovery over the years. Recent studies, however, have focused on the development of models tha