Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Jonathan C. P. Roos"'
Publikováno v:
New England Journal of Medicine. 382:1958-1960
Publikováno v:
Current Opinion in Ophthalmology. 30:395-400
Purpose of review The use of dermal filler in the periocular area is increasing - both for functional and aesthetic indications. Hyaluronic acid fillers dominate the market; these treatments offer an alternative to some surgical procedures with the a
Autor:
Rachna Murthy, Jonathan C. P. Roos
Publikováno v:
Eye. 33:327-342
Autor:
Jonathan C. P. Roos, Rachna Murthy, V. Krishna K. Chatterjee, Alasdair Coles, Joanne L. Jones, Carla Moran
Publikováno v:
Eye. 33:223-229
Alemtuzumab-a monoclonal antibody targeting the CD52 glycoprotein expressed by most mature leucocytes-effectively decreases relapse rate and disability progression in early, relapsing-remitting multiple sclerosis (MS). However, secondary autoimmune d
Autor:
Daphne E.C. Boer, Maria J. Ferraz, Rianne Meijer, Kimberley C. Zwiers, Mina Mirzaian, Jonathan C. P. Roos, Johannes M. F. G. Aerts, Navraj S. Pannu, Marc D. Hazeu, Herman S. Overkleeft, Rolf G. Boot, André R. A. Marques, Marta Artola, Roelof Ottenhoff, Merel V. Baks, Timothy M. Cox
Publikováno v:
Journal of Lipid Research, 62. ELSEVIER
Journal of Lipid Research
Journal of Lipid Research, Vol 62, Iss, Pp 100018-(2021)
Journal of lipid research, 62:RA120001043. American Society for Biochemistry and Molecular Biology Inc.
Journal of Lipid Research
Journal of Lipid Research, Vol 62, Iss, Pp 100018-(2021)
Journal of lipid research, 62:RA120001043. American Society for Biochemistry and Molecular Biology Inc.
Deficiency of glucocerebrosidase (GBA), a lysosomal beta-glucosidase, causes Gaucher disease. The enzyme hydrolyzes beta-glucosidic substrates and transglucosylates cholesterol to cholesterol-p-glucoside. Here we show that recombinant human GBA also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f2f8307fc9146a377776a47bc11811f
https://hdl.handle.net/1887/3214386
https://hdl.handle.net/1887/3214386
Publikováno v:
Ophthalmic plastic and reconstructive surgery. 37(4)
Background Thyroid eye disease (TED) is characterized by orbital inflammation and complicated by extraocular muscle fibrosis. Treatment with rapamycin/sirolimus has been reported to improve ocular motility and disease manifestations in TED. Whether t
Autor:
Jonathan C. P. Roos, Rachna Murthy
Publikováno v:
Current opinion in ophthalmology. 30(5)
To offer an update on advances and controversies in the assessment, investigation and treatment of thyroid eye disease (TED), a disfiguring orbital autoimmune disease, which can manifest with diplopia and threaten not only sight - but also life.Devel
Autor:
Rachna Murthy, Jonathan C. P. Roos
BACKGROUND: Rapamycin (alternatively known as sirolimus) is a macrolide immunosuppressant commonly used for organ transplantation. It acts both on lymphocytes through the mechanistic target of rapamycin (mTOR) pathway to reduce their sensitivity to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98edb1518830005a97003edf4edbc760
https://europepmc.org/articles/PMC6461882/
https://europepmc.org/articles/PMC6461882/
Imaging in thyroid eye disease (TED) is used to exclude other diagnoses, assess for apical crowding and plan surgery. But to quantify TED activity objectively, subjective clinical scoring assessments remain the norm. Magnetic resonance imaging (MRI)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::192e9495fce388d009f100cf332749e1
Autor:
Jonathan C. P. Roos, Kris S. Moe, Paul A. Gardner, Michael K. Yoon, Suzanne K. Freitag, Sophie D. Liao, Raymond Sacks, Richard G. Douglas, Nahyoung Grace Lee, Adam P. Campbell, Carl H. Snyderman, Vijay R. Ramakrishnan, Richard J. Harvey, Rodney J. Schlosser, S. Tonya Stefko, Elliott Mappus, Alkis J. Psaltis, Geoffrey A. Wilcsek, Joanne Rimmer, Catherine J. Choi, Henry P. Barham, Daniel R. Lefebvre, Dean M. Cestari, Katherine L. Reinshagen, Darlene Lubbe, Raewyn Campbell, Jordan T. Glicksman, Benjamin S. Bleier, Bo Young Chun, Nithin D. Adappa, Valerie J. Lund, Saul N. Rajak, Catherine Banks, George A. Scangas, Lora R. Dagi Glass, James N. Palmer, Ralph Metson, Zachary M. Soler, Geoffrey E. Rose, Hugh D. Curtin, Natalie Wolkow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9cd701ca1e5e83017e3e36155ef0413
https://doi.org/10.1055/b-006-160139
https://doi.org/10.1055/b-006-160139