NRF2-Dependent Placental Effects Vary by Sex and Dose following Gestational Exposure to Ultrafine Particles

Autor: Jonathan C. Behlen, Carmen H. Lau, Drew Pendleton, Yixin Li, Aline Rodrigues Hoffmann, Michael C. Golding, Renyi Zhang, Natalie M. Johnson

Publikováno v: Antioxidants, Vol 11, Iss 2, p 352 (2022)

Exposure to ultrafine particles (UFPs, PM0.1) during pregnancy triggers placental oxidative stress and inflammation, similar to fine PM (PM2.5). The Nrf2 gene encodes a redox-sensitive transcription factor that is a major regulator of antioxidant and

Externí odkaz: https://doaj.org/article/b756b93dd16b42c69026de91e9b7c6ac

Inhibition of Sirtuin-1 hyperacetylates p53 and abrogates SIRT1-p53 interaction in Cr(VI)-Induced Apoptosis in the ovary

Autor: Kirthiram K. Sivakumar, Jone A. Stanley, Jonathan C. Behlen, Liga Wuri, Sudipta Dutta, John Wu, Joe A. Arosh, Sakhila K. Banu

Publikováno v: Reprod Toxicol

Environmental contamination with hexavalent chromium, Cr(VI), has been increasing in the United States as well as in developing countries. Exposure to Cr(VI) predisposes the human population to various diseases, including cancer, infertility, and dev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::366b1ca7b0ff72a7b7dd142036fae5bb
https://europepmc.org/articles/PMC9884489/

Oxidative Stress and Thyroid Disorders

Autor: Loganayaki Periyasamy, Sridhar Muthusami, Kokelavani Nampalli Babu, Sneha Krishnamoorthy, Jonathan C. Behlen, Jone A. Stanley

Publikováno v: Handbook of Oxidative Stress in Cancer: Mechanistic Aspects ISBN: 9789811545016
Handbook of Oxidative Stress in Cancer: Mechanistic Aspects

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2f523031ef3ed8254d1e7c1e826df7b
https://doi.org/10.1007/978-981-15-4501-6_1-1