Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jonathan C. Bean"'
Autor:
Meng Yu, Jonathan C. Bean, Hailan Liu, Yang He, Yongjie Yang, Xing Cai, Kaifan Yu, Zhou Pei, Hesong Liu, Longlong Tu, Kristine M. Conde, Mengjie Wang, Yongxiang Li, Na Yin, Nan Zhang, Junying Han, Nikolas A. Scarcelli, Pingwen Xu, Yanlin He, Yong Xu, Chunmei Wang
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Background Pro-opiomelanocortin (POMC) neurons play a sexually dimorphic role in body weight and glucose balance. However, the mechanisms for the sex differences in POMC neuron functions are not fully understood. Results We detected small co
Externí odkaz:
https://doaj.org/article/680c6cceb37441439954e4c7a5a4af42
Autor:
Longlong Tu, Jonathan C. Bean, Yang He, Hailan Liu, Meng Yu, Hesong Liu, Nan Zhang, Na Yin, Junying Han, Nikolas A. Scarcelli, Kristine M. Conde, Mengjie Wang, Yongxiang Li, Bing Feng, Peiyu Gao, Zhao-Lin Cai, Makoto Fukuda, Mingshan Xue, Qingchun Tong, Yongjie Yang, Lan Liao, Jianming Xu, Chunmei Wang, Yanlin He, Yong Xu
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 14 (2023)
Glucose is the basic fuel essential for maintenance of viability and functionality of all cells. However, some neurons — namely, glucose-inhibited (GI) neurons — paradoxically increase their firing activity in low-glucose conditions and decrease
Externí odkaz:
https://doaj.org/article/db791eea21694462991bc49ae75e64ed
Autor:
Emily J. Koller, Melissa Comstock, Jonathan C. Bean, Gabriel Escobedo, Kyung-Won Park, Joanna L. Jankowsky
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 3 (2023)
Externí odkaz:
https://doaj.org/article/9959df154a824681ad9bec4e58132801
Autor:
Zhou Pei, Yang He, Jonathan C. Bean, Yongjie Yang, Hailan Liu, Meng Yu, Kaifan Yu, Ilirjana Hyseni, Xing Cai, Hesong Liu, Na Qu, Longlong Tu, Kristine M. Conde, Mengjie Wang, Yongxiang Li, Na Yin, Nan Zhang, Junying Han, Camille HS. Potts, Nikolas A. Scarcelli, Zili Yan, Pingwen Xu, Qi Wu, Yanlin He, Yong Xu, Chunmei Wang
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Pro-opiomelanocortin (POMC) neurons are important for the regulation of body weight and glucose balance. The inhibitory tone to POMC neurons is mediated primarily by the GABA receptors. However, the detailed mechanisms and functions of GABA receptors
Externí odkaz:
https://doaj.org/article/eea12f00433243548987cea032786218
Autor:
Emily J. Koller, Melissa Comstock, Jonathan C. Bean, Gabriel Escobedo, Kyung-Won Park, Joanna L. Jankowsky
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 5 (2022)
Although a large number of mouse models have been made to study Alzheimer's disease, only a handful allow experimental control over the location or timing of the protein being used to drive pathology. Other fields have used the Cre and the tamoxifen-
Externí odkaz:
https://doaj.org/article/3ded16675ab54881a1cd0e364dba4235
Autor:
Yang He, Bas Brouwers, Hesong Liu, Hailan Liu, Katherine Lawler, Edson Mendes de Oliveira, Dong-Kee Lee, Yongjie Yang, Aaron R. Cox, Julia M. Keogh, Elana Henning, Rebecca Bounds, Aliki Perdikari, Vikram Ayinampudi, Chunmei Wang, Meng Yu, Longlong Tu, Nan Zhang, Na Yin, Junying Han, Nikolas A. Scarcelli, Zili Yan, Kristine M. Conde, Camille Potts, Jonathan C. Bean, Mengjie Wang, Sean M. Hartig, Lan Liao, Jianming Xu, Inês Barroso, Jacek Mokrosinski, Yong Xu, I. Sadaf Farooqi
Funder: National Institute for Health Research (NIHR)
Serotonin reuptake inhibitors and receptor agonists are used to treat obesity, anxiety and depression. Here we studied the role of the serotonin 2C receptor (5-HT2CR) in weight regulation and
Serotonin reuptake inhibitors and receptor agonists are used to treat obesity, anxiety and depression. Here we studied the role of the serotonin 2C receptor (5-HT2CR) in weight regulation and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18e7fcce37e71b8dfb698909029b7e74
https://www.repository.cam.ac.uk/handle/1810/344906
https://www.repository.cam.ac.uk/handle/1810/344906
Publikováno v:
J Immunol
In mice, a subset of cardiac macrophages and Kupffer cells derive from fetal precursors, seed the developing tissues, self-renew locally, and persist into adulthood. In this study we investigated how these cells survive acute systemic inflammation. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a17a1fadd298cfa7b25550266e821c42
https://doi.org/10.4049/jimmunol.2001324
https://doi.org/10.4049/jimmunol.2001324
Autor:
Hui Feng Jiao, Dong Min Yin, Wen Cheng Xiong, Yong Jun Chen, Feng Qing Hou, Yisheng Lu, Jonathan C. Bean, Fang Liu, Xiang Dong Sun, Lin Lin Bi, Bao Ming Li, Tian Ming Gao, Xihui Liu, Lin Mei
Publikováno v:
Neuron. 111:1684
SummaryInhibitory neurotransmission in amygdala is important for fear learning and memory. However, mechanisms that control the inhibitory activity in amygdala are not well understood. We provide evidence that neuregulin 1 (NRG1) and its receptor Erb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c57ee7a4d7118ae69251e5e3b5719c36
https://doi.org/10.1016/j.neuron.2023.04.029
https://doi.org/10.1016/j.neuron.2023.04.029
Publikováno v:
J Vis Exp
Immunohistochemical staining of mouse brains is a routine technique commonly used in neuroscience to investigate central mechanisms underlying the regulation of energy metabolism and other neurobiological processes. However, the quality, reliability,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8050b2d6737784d3969b91ba42b96c15
https://doi.org/10.3791/62876
https://doi.org/10.3791/62876
Autor:
Emily J. Koller, Melissa Comstock, Jonathan C. Bean, Gabriel Escobedo, Kyung-Won Park, Joanna L. Jankowsky
Publikováno v:
Disease modelsmechanisms. 15(5)
Although a large number of mouse models have been made to study Alzheimer's disease, only a handful allow experimental control over the location or timing of the protein being used to drive pathology. Other fields have used the Cre and the tamoxifen-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6128ea257fda571d5a2f9072fe90e335
https://pubmed.ncbi.nlm.nih.gov/35394029
https://pubmed.ncbi.nlm.nih.gov/35394029