Zobrazeno 1 - 5
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pro vyhledávání: '"Jonathan C Tong"'
Publikováno v:
Annals of the New York Academy of Sciences. 958:182-189
Molecular mimicry between the 65-kDa isoform of glutamic acid decarboxylase (GAD65) and the protein 2C (P2C) of Coxsackie B4 virus (CBV) may initiate human type 1 diabetes. GAD65 contains a motif that has a 6-amino acid identity with CBV-P2C (PEVKEK)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4cb4fad951ffd770fc004efa40c5984
https://doi.org/10.1111/j.1749-6632.2002.tb02966.x
https://doi.org/10.1111/j.1749-6632.2002.tb02966.x
Autor:
Mark A. Myers, Ossama El-Kabbani, Jonathan C Tong, Merrill J. Rowley, Robyn Elizabeth Gray, Marita Scealy, Gustavo Fenalti
Publikováno v:
Annals of the New York Academy of Sciences. 1005:250-252
The 65-kDa isoform of glutamic acid decarboxylase (GAD65) is a major autoantigen in type 1 diabetes, and most patients have serum antibodies reactive with conformational epitopes on the GAD65 molecule. The aims of this study were to prepare mutants o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b323c4fc10e94c55b84d601df35c27f
https://doi.org/10.1196/annals.1288.037
https://doi.org/10.1196/annals.1288.037
Autor:
Mark A, Myers, Gustavo, Fenalti, Robyn, Gray, Marita, Scealy, Jonathan C, Tong, Ossama, El-Kabbani, Merrill J, Rowley
Publikováno v:
Annals of the New York Academy of Sciences. 1005
The 65-kDa isoform of glutamic acid decarboxylase (GAD65) is a major autoantigen in type 1 diabetes, and most patients have serum antibodies reactive with conformational epitopes on the GAD65 molecule. The aims of this study were to prepare mutants o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8dcbb969b01349f229e104c31a7d0477
https://pubmed.ncbi.nlm.nih.gov/14679070
https://pubmed.ncbi.nlm.nih.gov/14679070
Publikováno v:
Monash University
Background and aims: Glutamic acid decarboxylase (GAD, EC 4.1.1.15) catalyses the conversion of glutamate to γ-aminobutyric acid (GABA). The 65 kDa isoform, GAD65 is a potent autoantigen in type 1 diabetes, whereas GAD67 is not. A hybrid cDNA was cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e318336cfd49a9c955b56a4352c845df
https://pubmed.ncbi.nlm.nih.gov/12067524
https://pubmed.ncbi.nlm.nih.gov/12067524
Autor:
Jonathan C Tong, Ian R. Mackay, Marita Scealy, Merrill J. Rowley, Janet M. Davies, Mark A. Myers, James C. Whisstock
Publikováno v:
ResearcherID
Scopus-Elsevier
Monash University
Scopus-Elsevier
Monash University
The major diabetes autoantigen, glutamic acid decarboxylase (GAD65), contains a region of sequence similarity, including six identical residues PEVKEK, to the P2C protein of coxsackie B virus, suggesting that cross-reactivity between coxsackie B viru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76000077be5d2ded28947e56a8772fa1
https://pubmed.ncbi.nlm.nih.gov/11034389
https://pubmed.ncbi.nlm.nih.gov/11034389