Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Jonathan C Poe"'
Autor:
Jonathan C Poe, Susan H Smith, Karen M Haas, Koichi Yanaba, Takeshi Tsubata, Takashi Matsushita, Thomas F Tedder
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22464 (2011)
Aberrant CD40 ligand (CD154) expression occurs on both T cells and B cells in human lupus patients, which is suggested to enhance B cell CD40 signaling and play a role in disease pathogenesis. Transgenic mice expressing CD154 by their B cells (CD154(
Externí odkaz:
https://doaj.org/article/adb0b0c83e0149bdbc2ca6c31dc1696f
Autor:
Jonathan C. Poe, Jiyuan Fang, Dadong Zhang, Marissa R. Lee, Rachel A. DiCioccio, Hsuan Su, Xiaodi Qin, Jennifer Y. Zhang, Jonathan Visentin, Sonali J. Bracken, Vincent T. Ho, Kathy S. Wang, Jeremy J. Rose, Steven Z. Pavletic, Frances T. Hakim, Wei Jia, Amy N. Suthers, Itaevia M. Curry-Chisolm, Mitchell E. Horwitz, David A. Rizzieri, William C. McManigle, Nelson J. Chao, Adela R. Cardones, Jichun Xie, Kouros Owzar, Stefanie Sarantopoulos
Publikováno v:
JCI Insight, Vol 8, Iss 11 (2023)
Alloreactivity can drive autoimmune syndromes. After allogeneic hematopoietic stem cell transplantation (allo-HCT), chronic graft-versus-host disease (cGVHD), a B cell–associated autoimmune-like syndrome, commonly occurs. Because donor-derived B ce
Externí odkaz:
https://doaj.org/article/6512c743367141a7ad578b252db65faa
Autor:
Jonathan Visentin, Wei Jia, Jonathan C Poe, Hsuan Su, Sofian Christina, Rachel A. DiCioccio, Itaevia Curry-Chisolm, Fahmin Basher, Sonali Bracken, Vincent T Ho, Vanja Sisirak, Mitchell E. Horwitz, Nelson J. Chao, Stefanie Sarantopoulos
Publikováno v:
Transplantation and Cellular Therapy. 29:S58-S59
Autor:
Jonathan C Poe, Jiyuan Fang, Dadong Zhang, Marissa R Lee, Rachel A DiCioccio, Hsuan Su, Xiaodi Qin, Jennifer Zhang, Jonathan Visentin, Sonali J Bracken, Vincent T Ho, Kathy S Wang, Jeremy J Rose, Steven Z Pavletic, Frances T Hakim, Wei Jia, Amy N Suthers, Itaevia Curry-Chisolm, Mitchell E Horwitz, David A Rizzieri, William McManigle, Nelson J Chao, Adela R Cardones, Jichun Xie, Kouros Owzar, Stefanie Sarantopoulos
Alloreactivity can drive autoimmune syndromes. After allogeneic hematopoietic stem cell transplantation (allo-HCT) chronic graft-versus-host disease (cGVHD), a B cell-mediated autoimmune-like syndrome, commonly occurs. Because donor-derived B cells c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c473db4c87738c7f0e79af6c6c5d1f7b
https://doi.org/10.1101/2022.10.13.512162
https://doi.org/10.1101/2022.10.13.512162
Autor:
Daniel R. Saban, Jonathan C. Poe, Vedran Radojcic, Diana M. Cardona, Ivan Maillard, Stefanie Sarantopoulos, Amy N. Suthers, Itaevia M. Curry-Chisolm, Hsuan Su, Glenn K. Matsushima, Zhiguo Li, Sarah Anand, Wei Jia, Jeffrey C. Rathmell, Nelson J. Chao, Kazuhiro Imai, Nancy J. Reyes, Benny J. Chen, Rachel A. DiCioccio
Publikováno v:
Blood. 137:2544-2557
Patients with chronic graft-versus-host disease (cGVHD) have increased B cell–activating factor (BAFF) levels, but whether BAFF promotes disease after allogeneic bone marrow transplantation (allo-BMT) remains unknown. In a major histocompatibility
Autor:
Hsuan, Su, Kazuhiro, Imai, Wei, Jia, Zhiguo, Li, Rachel A, DiCioccio, Jonathan S, Serody, Jonathan C, Poe, Benny J, Chen, Phuong L, Doan, Stefanie, Sarantopoulos
Publikováno v:
Frontiers in Immunology. 13
De novo immune responses to myeloid and other blood-borne tumors are notably limited and ineffective, making our ability to promote immune responses with vaccines a major challenge. While focus has been largely on cytotoxic cell-mediated tumor eradic
Autor:
Chenyu Lin, Rachel A. DiCioccio, Tarek Haykal, William C. McManigle, Zhiguo Li, Sarah M. Anand, Jonathan C. Poe, Sonali J. Bracken, Wei Jia, Edwin P. Alyea, Adela R. Cardones, Taewoong Choi, Cristina Gasparetto, Michael R. Grunwald, Therese Hennig, Yubin Kang, Gwynn D. Long, Richard Lopez, Melissa Martin, Kerry K. Minor, Victor L. Perez Quinones, Anthony D. Sung, Kristi Wiggins, Nelson J. Chao, Mitchell E. Horwitz, David A. Rizzieri, Stefanie Sarantopoulos
Publikováno v:
Transplantation and Cellular Therapy. 29:179.e1-179.e10
Autor:
Wei Jia, Nelson J. Chao, Jonathan Visentin, Benny J. Chen, Lauren S. Riley, Rachel A. DiCioccio, Serach C. Patterson, Sonali J. Bracken, Hsuan Su, Jonathan C. Poe, Stefanie Sarantopoulos
Publikováno v:
Blood. 138:3815-3815
After elucidating a role for aberrant B Cell Receptor (BCR) signaling in chronic graft versus host disease (cGVHD) (Allen et al, Blood. 2014;123:2108), we showed that the proximal BCR molecule SYK is a viable therapeutic target in mice and patients (
Autor:
Mayuka Horikawa, Tomomitsu Miyagaki, Veronique Minard-Colin, Masahiro Kamata, Jacquelyn M. Lykken, Jonathan C. Poe, Thomas F. Tedder
Publikováno v:
Blood. 127:1886-1895
Non-Hodgkin lymphoma (NHL) is the most commonly diagnosed hematologic cancer of adults in the United States, with the vast majority of NHLs deriving from malignant B lymphocytes that express cell surface CD20. CD20 immunotherapy (rituximab) is widely
Autor:
Yanzhe Gao, Zhiguo Li, Cyrus Vaziri, Jonathan C. Poe, Lisong Yang, Terry Magnuson, Satoshi Tateishi, Yuri Fedoriw, Siddhi Desai, Andrew M. Fedoriw, Yang Yang, Kimi Araki, Stefanie Sarantopoulos
Publikováno v:
Nucleic Acids Research
In cultured cancer cells the E3 ubiquitin ligase Rad18 activates Trans-Lesion Synthesis (TLS) and the Fanconi Anemia (FA) pathway. However, physiological roles of Rad18 in DNA damage tolerance and carcinogenesis are unknown and were investigated here