Zobrazeno 1 - 10
of 147
pro vyhledávání: '"Jonathan C Gewirtz"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Substance use disorder (SUD) represents a large and growing global health problem. Despite the strong addictive potency of drugs of abuse, only a minority of those exposed develop SUDs. While certain life experiences (e.g., childhood trauma) may incr
Externí odkaz:
https://doaj.org/article/963b85c8386947feb0104013a146db2f
Autor:
Andrew C. Harris, Peter Muelken, Shirelle X. Liu, John R. Smethells, Mark G. LeSage, Jonathan C. Gewirtz
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 18 (2024)
IntroductionSex differences in vulnerability to opioid use disorder (OUD) have been reported in some clinical and preclinical studies, but findings are mixed and further research is needed in this area. The goal of this study was to compare elasticit
Externí odkaz:
https://doaj.org/article/c1bdce34e4ec4230b6e23273cfd86151
Autor:
Shirelle X. Liu, Aarthi Ramakrishnan, Li Shen, Jonathan C. Gewirtz, Michael K. Georgieff, Phu V. Tran
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-17 (2024)
Abstract Background Iron deficiency (ID) during the fetal-neonatal period results in long-term neurodevelopmental impairments associated with pervasive hippocampal gene dysregulation. Prenatal choline supplementation partially normalizes these effect
Externí odkaz:
https://doaj.org/article/511ec710533a4bcf895fd68df659afb4
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
Individual differences in vulnerability to addiction have been widely studied through factor analysis (FA) in humans, a statistical method that identifies “latent” variables (variables that are not measured directly) that reflect the common varia
Externí odkaz:
https://doaj.org/article/95fad3e5f1e74d1a880d2c2511429d26
Autor:
Tatyana M. Matveeva, Garima Singh, Tate A. Gisslen, Jonathan C. Gewirtz, Michael K. Georgieff
Publikováno v:
Brain and Behavior, Vol 11, Iss 3, Pp n/a-n/a (2021)
Abstract Introduction Anemia is common in prematurely born infants due to blood loss resulting from frequent phlebotomies and may contribute to their neurobehavioral deficits. Preclinical models of phlebotomy‐induced anemia (PIA) have revealed meta
Externí odkaz:
https://doaj.org/article/50eb30740a164ae38e58bf66a275e7d3
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Oxytocin modulates social behaviours in mammals. Here the authors demonstrate that observational fear, a measure of empathy-like behaviour in rodents, is modulated by oxytocin.
Externí odkaz:
https://doaj.org/article/d58171a7bb1b47278b4bfea522bf9739
Publikováno v:
Brain and Behavior, Vol 9, Iss 10, Pp n/a-n/a (2019)
Abstract Background Studies of schizophrenia have pointed to the role of glutamate in its pathophysiology. Mice lacking D‐serine show impairments in neurotransmission through NMDA receptors and display behaviors consistent with features of schizoph
Externí odkaz:
https://doaj.org/article/a02c1bc7dcd140bdb1d4a5de4e2f3e72
Autor:
Ryan D. Webler, Desmond J. Oathes, Sanne J.H. van Rooij, Jonathan C. Gewirtz, Ziad Nahas, Shmuel M. Lissek, Alik S. Widge
Publikováno v:
Neurosci Biobehav Rev
Laboratory threat extinction paradigms and exposure-based therapy both involve repeated, safe confrontation with stimuli previously experienced as threatening. This fundamental procedural overlap supports laboratory threat extinction as a compelling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df42d5f584eb81e93104513ba9fbbfcd
https://europepmc.org/articles/PMC10210253/
https://europepmc.org/articles/PMC10210253/
Autor:
Shirelle X. Liu, Aarthi Ramakrishnan, Li Shen, Jonathan C. Gewirtz, Michael K. Georgieff, Phu V. Tran
Iron deficiency during the fetal-neonatal period results in long-term neurodevelopmental impairments associated with pervasive and widespread hippocampal gene dysregulation. Globally, fetal-neonatal iron deficiency produces both long-term activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc710bcb854c3c47ec53606e7d4a6230
https://doi.org/10.1101/2022.06.07.495122
https://doi.org/10.1101/2022.06.07.495122
Autor:
Mark G. LeSage, Andrew C. Harris, Zachary Haave, Jonathan C. Gewirtz, Yayi Swain, Peter Muelken, Annika Skansberg, Danielle Lanzdorf
Publikováno v:
Psychopharmacology (Berl)
Understanding factors contributing to individual differences in vulnerability to opioid addiction is essential for developing more effective preventions and treatments, yet few reliable behavioral predictors of subsequent opioid self-administration h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26947db686356fa65196451e868508f1
https://doi.org/10.1007/s00213-020-05532-w
https://doi.org/10.1007/s00213-020-05532-w