Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Jonathan Brostoff"'
Autor:
Adele Costabile, Sara Santarelli, Sandrine P Claus, Jeremy Sanderson, Barry N Hudspith, Jonathan Brostoff, Jane L Ward, Alison Lovegrove, Peter R Shewry, Hannah E Jones, Andrew M Whitley, Glenn R Gibson
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e111225 (2014)
A variety of foods have been implicated in symptoms of patients with Irritable Bowel Syndrome (IBS) but wheat products are most frequently cited by patients as a trigger. Our aim was to investigate the effects of breads, which were fermented for diff
Externí odkaz:
https://doaj.org/article/f73a9f98992144728bc5fd46c0ccc12e
Publikováno v:
Access Microbiology. 1
Background: The influence of gut microorganisms in health and disease is well documented, however, the role of yeasts has not been as widely studied as bacteria, despite associations with gastrointestinal disorders, such as Irritable Bowel Syndrome (
Autor:
Natalie J. Prescott, Liljana Petrovska, John Hermon-Taylor, Alex Boussioutas, Tim Elliott, Barry N. Hudspith, Jonathan Brostoff, Christopher G. Mathew, Neil B. Rayment, Jeremy D. Sanderson
Publikováno v:
Journal of Gastroenterology and Hepatology. 30:1265-1274
Background and Aim Escherichia coli can be isolated from lamina propria macrophages in Crohn's disease (CD), and their intramacrophage persistence may provide a stimulus for inflammation. To further determine the contributions of macrophage dysfuncti
Autor:
Jonathan Brostoff, Stephen Challacombe, Peter Milligan, Miranda Lomer, Jeremy D. Sanderson, Michael Escudier, Parul Patel, Helen Campbell
Publikováno v:
Journal of Oral Pathology & Medicine. 42:517-522
Background Orofacial granulomatosis (OFG) is a chronic granulomatous condition of the mouth, face and lips. Recent work demonstrates a high rate of atopy and silver birch sensitisation from skin prick testing (SPT). Oral allergy syndrome (OAS) is an
Autor:
Jonathan Brostoff, Barry N. Hudspith, Gareth Parkes, Liljana Petrovska, Kevin Whelan, Miranda Lomer, Neil B. Rayment, Jeremy D. Sanderson
Publikováno v:
Neurogastroenterology & Motility. 24:31-39
Background There is increasing evidence to support a role for the gastrointestinal microbiota in the etiology of irritable bowel syndrome (IBS). Given the evidence of an inflammatory component to IBS, the mucosa-associated microbiota potentially play
Autor:
Alexander J. Mentzer, Peter Milligan, Richard J. Cook, Jonathan Brostoff, Carlo Nunes, Penelope Shirlaw, Pritash Patel, Tim Elliott, Jeremy D. Sanderson, Timothy Poate, K Barnard, Miranda Lomer, Stephen Challacombe, Helen Campbell, Michael Escudier
Publikováno v:
Inflammatory Bowel Diseases. 17:2109-2115
Background: Orofacial granulomatosis (OFG) is a rare chronic inflammatory disease of unknown etiology sharing histological features with Crohn's disease (CD). This study aimed to 1) define the clinical presentation of OFG, 2) establish differentiatin
Autor:
Pritash Patel, Michael Escudier, Stephen Challacombe, Francesca Barone, Carlo Nunes, Jo Spencer, Jeremy D. Sanderson, Edward Odell, Laurent Boursier, Jonathan Brostoff
Publikováno v:
Inflammatory Bowel Diseases. 16:1051-1060
Background: Orofacial granulomatosis (OFG) is a chronic, disfiguring, granulomatous inflammation of the lips and oral mucosa. The pathogenesis is unknown, but it has been linked previously to Crohn's disease (CD) and more recently to dietary sensitiv
Publikováno v:
Tissue Antigens. 17:261-264
A group of patients with cutaneous sensitivity was compared with another group with cement dermatitis who showed sensitivity to chromate. HLA typing for A and B locus antigens demonstrated a 29% incidence of B21 in the nickel sensitive group (control
Publikováno v:
The American Journal of Gastroenterology. 103:1557-1567
Irritable bowel syndrome (IBS) is a chronic disorder characterized by abdominal pain, change in bowel habit, and bloating. It has traditionally been viewed as a disorder of visceral hypersensitivity heavily influenced by stress, and therefore therape
Autor:
Christopher G. Mathew, John Hermon-Taylor, Rebecca Hands, Tim Elliott, Alex Boussioutas, Natalie J. Prescott, Stephen A. Bustin, Liljana Petrovska, Jonathan Brostoff, Kirstin M. Taylor, Gareth Parkes, Neil B. Rayment, Barry N. Hudspith, Jeremy D. Sanderson
Publikováno v:
BMC Gastroenterology
Background Abnormal handling of E. coli by lamina propria (LP) macrophages may contribute to Crohn’s disease (CD) pathogenesis. We aimed to determine LP macrophage phenotypes in CD, ulcerative colitis (UC) and healthy controls (HC), and in CD, to c