Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Jonathan Blum"'
Autor:
Karin Grillberger, Eike Cöllen, Claudia Immacolata Trivisani, Jonathan Blum, Marcel Leist, Gerhard F. Ecker
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13170 (2023)
Neonicotinoid pesticides were initially designed in order to achieve species selectivity on insect nicotinic acetylcholine receptors (nAChRs). However, concerns arose when agonistic effects were also detected in human cells expressing nAChRs. In the
Externí odkaz:
https://doaj.org/article/b2467288b49f462b80918a907ad937e3
Autor:
Florian Seidel, Anna Cherianidou, Franziska Kappenberg, Miriam Marta, Nadine Dreser, Jonathan Blum, Tanja Waldmann, Nils Blüthgen, Johannes Meisig, Katrin Madjar, Margit Henry, Tamara Rotshteyn, Andreas Scholtz-Illigens, Rosemarie Marchan, Karolina Edlund, Marcel Leist, Jörg Rahnenführer, Agapios Sachinidis, Jan Georg Hengstler
Publikováno v:
Cells, Vol 11, Iss 21, p 3404 (2022)
Human-relevant tests to predict developmental toxicity are urgently needed. A currently intensively studied approach makes use of differentiating human stem cells to measure chemically-induced deviations of the normal developmental program, as in a r
Externí odkaz:
https://doaj.org/article/1c72b068b68a48ac9b8dc05a0289a26b
Autor:
Dominick J. Casciato, DPM, Ryan Stone, DPM, John Thompson, DPM, Marissa Venero, DPM, Michael Chiu, DPM, Jonathan Blum, DPM, FACFAS, Ian Barron, DPM, FACFAS, Christopher Hyer, DPM, MS, FACFAS
Publikováno v:
Foot & Ankle Surgery: Techniques, Reports & Cases, Vol 1, Iss 3, Pp 100044- (2021)
Charcot neuroarthropathy (CN) is a highly destructive, pathologic process with devastating consequences to foot structure and viability. The use of intramedullary fixation ‘superconstructs’ allows for ‘re-bar’ support of compromised bone and
Externí odkaz:
https://doaj.org/article/325208954a024434b72cde931ca2e286
Autor:
Dominick J. Casciato, Ryan Stone, John Thompson, Marissa Venero, Michael Chiu, Jonathan Blum, Ian Barron, Christopher Hyer
Publikováno v:
The Journal of Foot and Ankle Surgery. 62:377-381
Lateral column deterioration and subsequent loss of function poses a challenge for limb preservation in patients with Charcot neuroarthropathy (CN). Application of "superconstructs" provides stability and clinical improvement to an often-ulcerated la
Autor:
Michael Chiu, Christopher F. Hyer, Ryan Stone, Ian Barron, Jonathan Blum, Dominick J. Casciato, John Thompson, Marissa Venero
Publikováno v:
The Journal of Foot and Ankle Surgery. 61:1076-1080
Charcot neuroarthropathy (CN) is a highly destructive, pathologic process with devastating consequences to foot structure and viability. The use of intramedullary fixation "superconstructs" allows for "re-bar" support of compromised bone and allows f
Autor:
Jonathan Blum, Stefan Masjosthusmann, Kristina Bartmann, Farina Bendt, Xenia Dolde, Arif Dönmez, Nils Förster, Anna-Katharina Holzer, Ulrike Hübenthal, Hagen Eike Keßel, Sadiye Kilic, Jördis Klose, Melanie Pahl, Lynn-Christin Stürzl, Iris Mangas, Andrea Terron, Kevin M. Crofton, Martin Scholze, Axel Mosig, Marcel Leist, Ellen Fritsche
Developmental neurotoxicity (DNT) is a major safety concern for all chemicals of the human exposome. However, DNT data from animal studies are available for only a small percentage of manufactured compounds. Test methods with a higher throughput than
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04065f0054d0235280408ccf7d7668ba
https://zenodo.org/record/7752644
https://zenodo.org/record/7752644
Autor:
Hagen Eike Keßel, Stefan Masjosthusmann, Kristina Bartmann, Jonathan Blum, Arif Dönmez, Nils Förster, Jördis Klose, Axel Mosig, Melanie Pahl, Marcel Leist, Martin Scholze, Ellen Fritsche
In the field of hazard assessment, Benchmark concentrations (BMC) and their associated uncertainty are of particular interest for regulatory decision making. The BMC estimation consists of various statistical decisions to be made, which depend largel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd6e108bfa48313822ffb51452e55d5b
https://doi.org/10.1101/2022.10.18.512648
https://doi.org/10.1101/2022.10.18.512648
Autor:
Adrian Covaci, Julia Tigges, Mamta Behl, Marcel Leist, Stefan Masjosthusmann, Hagen Eike Keßel, Lynn-Christin Stürzl, Ulrike Hübenthal, Andrea Rossi, Melanie Pahl, Jördis Klose, Nils Förster, Jonathan Blum, Katharina Koch, Sabine Schneider, Xenia Dolde, Ellen Fritsche, Farina Bendt, Anna-Katharina Holzer, Kristina Bartmann, Selina Woeste
Publikováno v:
Cell biology and toxicology
Due to their neurodevelopmental toxicity, flame retardants (FRs) like polybrominated diphenyl ethers are banned from the market and replaced by alternative FRs, like organophosphorus FRs, that have mostly unknown toxicological profiles. To study thei
Autor:
Marcel Leist, Carola van der Wurp, Wiebke Albrecht, Franziska Kappenberg, Jörg Rahnenführer, Tim Brecklinghaus, Jan G. Hengstler, Jonathan Blum
Publikováno v:
Archives of Toxicology
Archives of toxicology, 94:3787-3798
Archives of toxicology, 94:3787-3798
In cell biology, pharmacology and toxicology dose-response and concentration-response curves are frequently fitted to data with statistical methods. Such fits are used to derive quantitative measures (e.g. EC20 values) describing the relationship bet