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pro vyhledávání: '"Jonathan Blay"'
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Introduction: CD26/dipeptidyl peptidase IV (DPP4) is a cell-surface glycoprotein present on most epithelial cells that modulates the local response to external signals. We have previously shown that the dietary flavone apigenin (4′,5,7-trihydroxyfl
Externí odkaz:
https://doaj.org/article/0efb74c5ee3842f6900cbc8db28faa44
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionColorectal cancer and other adult solid cancers pose a significant challenge for successful treatment because the tumor microenvironment both hinders the action of conventional therapeutics and suppresses the immune activities of infiltra
Externí odkaz:
https://doaj.org/article/f5326e5005bc4b328c0d176efedb3a2b
Autor:
Judah Glogauer, Jonathan Blay
Publikováno v:
Cancer Reports, Vol 5, Iss 2, Pp n/a-n/a (2022)
Abstract Background The morbidity and mortality of cancer are significantly impacted by the invasive and metastatic potential of particular subgroups of malignant cells within a tumor. The particular pre‐metastatic properties of cancerous cells are
Externí odkaz:
https://doaj.org/article/863211d80b694cd4a8f70ea65c488409
Autor:
Eva F. DeRango-Adem, Jonathan Blay
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Apigenin (4′, 5, 7-trihydroxyflavone) is a plant flavone that has been found to have various actions against cancer cells. We evaluated available evidence to determine whether it is feasible for apigenin to have such effects in human patients.Apige
Externí odkaz:
https://doaj.org/article/89063a2a05ce4629a71f4ba13e2a1b23
Autor:
Deep Patel, Jonathan Blay
Publikováno v:
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 43(1)
Peripheral human blood is a readily-accessible source of patient material in which circulating tumour cells (CTCs) can be found. Their isolation and characterization holds the potential to provide prognostic value for various solid cancers. Enumerati
Autor:
Kelly Smith, Karin Hahn, Jonathan Blay, Venita Harris, Mira Maximos, Feng Chang, Thomas McFarlane
Publikováno v:
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners. 28(8)
Objective A prospective open-label randomized controlled trial to assess the role of a picture-based medication calendar on adherence to antiemetic regimens for adult patients receiving chemotherapy and assess the effect on other medication taking be
Autor:
Judah Glogauer, Jonathan Blay
Publikováno v:
Cancer Reports, Vol 5, Iss 2, Pp n/a-n/a (2022)
Background The morbidity and mortality of cancer are significantly impacted by the invasive and metastatic potential of particular subgroups of malignant cells within a tumor. The particular pre‐metastatic properties of cancerous cells are thus a c
Autor:
Nilmini Mendis, Paul A. Spagnuolo, Medhat Ibrahim, Spencer I T Berg, Jonathan Blay, Alessia Roma, Christina Ma, Rowena L Rodrigo, Elena Kreinin
Publikováno v:
Autophagy. 15:900-907
Macroautophagy/autophagy, a pathway by which cellular components are sequestered and degraded in response to homeostatic and cell stress-related signals, is required to preserve hematopoietic stem and progenitor cell function. Loss of chromosomal reg
Publikováno v:
Food Science & Nutrition. 8
Apigenin upregulation of CD26/DPPIV on colon epithelial cells requires inhibition of casein kinase 2
Publikováno v:
Food Science & Nutrition
Food Science & Nutrition, 8(10):5321-5329
Food Science & Nutrition, Vol 8, Iss 10, Pp 5321-5329 (2020)
Food Science & Nutrition, 8(10):5321-5329
Food Science & Nutrition, Vol 8, Iss 10, Pp 5321-5329 (2020)
CD26/DPPIV is a cell surface glycoprotein found on cells of the intestinal epithelium including those of the colon. We have previously shown that the dietary flavone apigenin (4′,5,7‐trihydroxyflavone) upregulates CD26/DPPIV on colon cells. Flavo