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Autor:
David H. Magers, Sarah G Zetterholm, Kayla E Warren, Leeann Boutwell, Jordan Cauley, John C Prather, Jonathan Bethea, Nathan I. Hammer, Shelley A Smith, Genevieve A. Verville, Christopher Boland
Publikováno v:
The Journal of Physical Chemistry B. 122:8805-8811
Trimethylamine N-oxide (TMAO) and urea are two important osmolytes with their main significance to the biophysical field being in how they uniquely interact with proteins. Urea is a strong protein destabilizing agent, whereas TMAO is known to counter