Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jonathan Barroso-González"'
Autor:
Sara Marrero-Hernández, Daniel Márquez-Arce, Romina Cabrera-Rodríguez, Judith Estévez-Herrera, Silvia Pérez-Yanes, Jonathan Barroso-González, Ricardo Madrid, José-David Machado, Julià Blanco, Agustín Valenzuela-Fernández
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
HIV Nef is a central auxiliary protein in HIV infection and pathogenesis. Our results indicate that HDAC6 promotes the aggresome/autophagic degradation of the viral polyprotein Pr55Gag to inhibit HIV-1 production. Nef counteracts this antiviral activ
Externí odkaz:
https://doaj.org/article/29d60b530a264db38f12f86bb3308796
Autor:
Katelyn M. Atkins, Laura L. Thomas, Jonathan Barroso-González, Laurel Thomas, Sylvain Auclair, Jun Yin, Hyeog Kang, Jay H. Chung, Jimmy D. Dikeakos, Gary Thomas
Publikováno v:
Cell Reports, Vol 8, Iss 5, Pp 1545-1557 (2014)
SIRT1 regulates the DNA damage response by deacetylating p53, thereby repressing p53 transcriptional output. Here, we demonstrate that the sorting protein PACS-2 regulates SIRT1-mediated deacetylation of p53 to modulate the DNA damage response. PACS-
Externí odkaz:
https://doaj.org/article/77026dbf1a5d4733a008cd6320ee59b9
Autor:
Nicole Kaminski, Anne R. Wondisford, Youngho Kwon, Michelle Lee Lynskey, Ragini Bhargava, Jonathan Barroso-González, Laura García-Expósito, Boxue He, Meng Xu, Dattatreya Mellacheruvu, Simon C. Watkins, Mauro Modesti, Kyle M. Miller, Alexey I. Nesvizhskii, Huaiying Zhang, Patrick Sung, Roderick J. O’Sullivan
Publikováno v:
Molecular Cell
Molecular Cell, 2022, S1097-2765 (22), pp.00935-2. ⟨10.1016/j.molcel.2022.09.025⟩
Molecular Cell, 2022, S1097-2765 (22), pp.00935-2. ⟨10.1016/j.molcel.2022.09.025⟩
International audience; Alternative lengthening of telomeres (ALT) is a homology-directed repair (HDR) mechanism of telomere elongation that controls proliferation in subsets of aggressive cancer. Recent studies have revealed that telomere repeat-con
Autor:
Ian D. Waddell, Robert W. Sobol, Kate M. Smith, Justin L. Roncaioli, Felipe da Veiga Leprevost, Song My Hoang, Dattatreya Mellacharevu, Dominique Ray-Gallet, Michelle L. Lynskey, Roderick J. O’Sullivan, Ragini Bhargava, Jonathan Barroso-González, Nicole Kaminski, Geneviève Almouzni, Anne R. Wondisford, Jianfeng Li, Donald J. Ogilvie, Alexey I. Nesvizhskii, Dominic I. James, Callen T. Wallace, Simon C. Watkins, Laura García-Expósito
Publikováno v:
Nature Structural and Molecular Biology
Nature Structural and Molecular Biology, Nature Publishing Group, 2020, 27 (12), pp.1152-1164. ⟨10.1038/s41594-020-0512-7⟩
Nature Structural & Molecular Biology
Nature Structural and Molecular Biology, 2020, 27 (12), pp.1152-1164. ⟨10.1038/s41594-020-0512-7⟩
Nat Struct Mol Biol
Nature Structural and Molecular Biology, Nature Publishing Group, 2020, 27 (12), pp.1152-1164. ⟨10.1038/s41594-020-0512-7⟩
Nature Structural & Molecular Biology
Nature Structural and Molecular Biology, 2020, 27 (12), pp.1152-1164. ⟨10.1038/s41594-020-0512-7⟩
Nat Struct Mol Biol
International audience; The synthesis of poly(ADP-ribose) (PAR) reconfigures the local chromatin environment and recruits DNA-repair complexes to damaged chromatin. PAR degradation by poly(ADP-ribose) glycohydrolase (PARG) is essential for progressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04d45f0c33f255ca7323659e74359498
https://hal.sorbonne-universite.fr/hal-03138406
https://hal.sorbonne-universite.fr/hal-03138406
Autor:
Jonathan Barroso-González, Laura García-Expósito, Song My Hoang, Michelle L. Lynskey, Justin L. Roncaioli, Arundhati Ghosh, Callen T. Wallace, Marco de Vitis, Mauro Modesti, Kara A. Bernstein, Saumendra N. Sarkar, Simon C. Watkins, Roderick J. O’Sullivan
Publikováno v:
Molecular Cell
Molecular Cell, 2019, 76 (1), pp.11-26.e7. ⟨10.1016/j.molcel.2019.06.043⟩
Mol Cell
Molecular Cell, 2019, 76 (1), pp.217. ⟨10.1016/j.molcel.2019.08.009⟩
Molecular Cell, Elsevier, 2019, 76 (1), pp.217. ⟨10.1016/j.molcel.2019.08.009⟩
Molecular Cell, Elsevier, 2019, 76 (1), pp.11-26.e7. ⟨10.1016/j.molcel.2019.06.043⟩
Molecular Cell, 2019, 76 (1), pp.11-26.e7. ⟨10.1016/j.molcel.2019.06.043⟩
Mol Cell
Molecular Cell, 2019, 76 (1), pp.217. ⟨10.1016/j.molcel.2019.08.009⟩
Molecular Cell, Elsevier, 2019, 76 (1), pp.217. ⟨10.1016/j.molcel.2019.08.009⟩
Molecular Cell, Elsevier, 2019, 76 (1), pp.11-26.e7. ⟨10.1016/j.molcel.2019.06.043⟩
Alternative Lengthening of Telomeres (ALT) is a homology-directed repair (HDR) mechanism of telomere elongation that controls proliferation in aggressive cancers. We show that the disruption of RAD51-associated protein 1 (RAD51AP1) in ALT+ cancer cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11988a7d954948510156c0d9a0b7fe6e
https://hal.science/hal-02383646
https://hal.science/hal-02383646
Autor:
Christopher J. Bakkenist, Jonathan Barroso-González, Julieta Martino, Moiseeva Tn, Gregory J. Brunette, Roderick J. O’Sullivan, Chelsea M Smith, Kara A. Bernstein
Publikováno v:
Nucleic Acids Research
RAD51 plays a central role in homologous recombination during double-strand break repair and in replication fork dynamics. Misregulation of RAD51 is associated with genetic instability and cancer. RAD51 is regulated by many accessory proteins includi
Autor:
Jonathan Barroso-González, Laura García-Expósito, Pablo Galaviz, Michelle Lee Lynskey, Joshua A.M. Allen, SongMy Hoang, Simon C. Watkins, Hilda A. Pickett, Roderick J. O’Sullivan
Publikováno v:
Cell reports
SUMMARY Alternative lengthening of telomeres (ALT) is a telomere-elongation mechanism observed in ~15% of cancer subtypes. Current models indicate that ALT is mediated by homology-directed repair mechanisms. By disrupting MSH6 gene expression, we sho
Autor:
Callen T. Wallace, Patricia L. Opresko, Marietta Y.W.T. Lee, Jean-Sébastien Hoffmann, Elodie Bournique, Jonathan Barroso-González, Valérie Bergoglio, Arindam Bose, Justin L. Roncaioli, Laura García-Expósito, Simon C. Watkins, Sufang Zhang, Roderick J. O’Sullivan
Publikováno v:
Cell Reports
Cell Reports, Elsevier Inc, 2016, 17 (7), pp.1858-1871. ⟨10.1016/j.celrep.2016.10.048⟩
Cell reports
Cell Reports, Vol 17, Iss 7, Pp 1858-1871 (2016)
Cell Reports, Elsevier Inc, 2016, 17 (7), pp.1858-1871. ⟨10.1016/j.celrep.2016.10.048⟩
Cell reports
Cell Reports, Vol 17, Iss 7, Pp 1858-1871 (2016)
SUMMARY Cancer cells rely on the activation of telomerase or the alternative lengthening of telomeres (ALT) pathways for telomere maintenance and survival. ALT involves homologous recombination (HR)-dependent exchange and/or HR-associated synthesis o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38d5489d70ea94d6dda9ccac5e414f83
https://hal.archives-ouvertes.fr/hal-02325725
https://hal.archives-ouvertes.fr/hal-02325725
Autor:
José-David Machado, Laura García-Expósito, Isabel Puigdomènech, Julià Blanco, Agustín Valenzuela-Fernández, Jonathan Barroso-González
Publikováno v:
Molecular Biology of the Cell
As Arf6 is key to coordinating plasma membrane trafficking and regulates cellular invasion by several microorganisms, the authors studied Arf6 function during early HIV-1 infection. The data suggest that HIV-1 requires Arf6-driven plasma membrane dyn
Autor:
Laura García-Expósito, Jonathan Barroso-González, Agustín Valenzuela-Fernández, José-David Machado
Publikováno v:
Journal of Biological Chemistry. 284:2419-2434
Clathrin-coated vesicles are responsible for the trafficking of several internalized biological cargos. We have observed that the endogenous F-actin-linker moesin co-distributes with constitutive components of clathrin-coated structures. Total intern