Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Jonathan B. Olsen"'
Autor:
Jonathan B. Olsen, Loksum Wong, Steven Deimling, Amanda Miles, Hongbo Guo, Yue Li, Zhaolei Zhang, Jack F. Greenblatt, Andrew Emili, Vincent Tropepe
Publikováno v:
Stem Cell Reports, Vol 7, Iss 3, Pp 454-470 (2016)
Proliferating progenitor cells undergo changes in competence to give rise to post-mitotic progeny of specialized function. These cell-fate transitions typically involve dynamic regulation of gene expression by histone methyltransferase (HMT) complexe
Externí odkaz:
https://doaj.org/article/dee9e35879264fc6ad3ab9eb6f68e846
Autor:
Edyta Marcon, Zuyao Ni, Shuye Pu, Andrei L. Turinsky, Sandra Smiley Trimble, Jonathan B. Olsen, Rosalind Silverman-Gavrila, Lorelei Silverman-Gavrila, Sadhna Phanse, Hongbo Guo, Guoqing Zhong, Xinghua Guo, Peter Young, Swneke Bailey, Denitza Roudeva, Dorothy Zhao, Johannes Hewel, Joyce Li, Susanne Gräslund, Marcin Paduch, Anthony A. Kossiakoff, Mathieu Lupien, Andrew Emili, Shoshana J. Wodak, Jack Greenblatt
Publikováno v:
Cell Reports, Vol 8, Iss 1, Pp 297-310 (2014)
Chromatin regulation is driven by multicomponent protein complexes, which form functional modules. Deciphering the components of these modules and their interactions is central to understanding the molecular pathways these proteins are regulating, th
Externí odkaz:
https://doaj.org/article/1fec600c0aea446f95652573d57c6bfd
Autor:
Louis Stancato, Peter Houghton, Sean Buchanan, Xueqian Gong, Jonathan B. Olsen, Philip Iversen, Philip Ebert, Alle B. VanWye, Jack Dempsey, Yue Webster, Julie Stewart, Simone Gupta, Wayne Blosser, Robert Flack, Jennifer Stephens, Matthew Renschler, Terry Shackleford, Caitlin D. Lowery, Michele Dowless
Supplementary Tables S1-S3, Figures S1-S4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::036402dbac2178ab68e7cff483293ae3
https://doi.org/10.1158/1078-0432.22470711
https://doi.org/10.1158/1078-0432.22470711
Autor:
Louis Stancato, Peter Houghton, Sean Buchanan, Xueqian Gong, Jonathan B. Olsen, Philip Iversen, Philip Ebert, Alle B. VanWye, Jack Dempsey, Yue Webster, Julie Stewart, Simone Gupta, Wayne Blosser, Robert Flack, Jennifer Stephens, Matthew Renschler, Terry Shackleford, Caitlin D. Lowery, Michele Dowless
Purpose:Ewing sarcoma (ES) is a rare and highly malignant cancer that occurs in the bone and surrounding tissue of children and adolescents. The EWS/ETS fusion transcription factor that drives ES pathobiology was previously demonstrated to modulate c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2123f2418816e146f9f13a60e21f128f
https://doi.org/10.1158/1078-0432.c.6527661
https://doi.org/10.1158/1078-0432.c.6527661
Autor:
Louis Stancato, Philip J. Ebert, Yue Webster, Alle B VanWye, Robert S. Flack, Xueqian Gong, Sean Buchanan, Caitlin D. Lowery, Jack A. Dempsey, Terry J Shackleford, Michele Dowless, Jennifer R. Stephens, Jonathan B. Olsen, Peter J. Houghton, Matthew Renschler, Philip W. Iversen, Wayne Blosser, Simone Gupta, Julie Stewart
Publikováno v:
Clinical Cancer Research. 24:6028-6039
Purpose: Ewing sarcoma (ES) is a rare and highly malignant cancer that occurs in the bone and surrounding tissue of children and adolescents. The EWS/ETS fusion transcription factor that drives ES pathobiology was previously demonstrated to modulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1d9c823c72453170d255553219208e8
https://doi.org/10.1158/1078-0432.ccr-18-1256
https://doi.org/10.1158/1078-0432.ccr-18-1256
Autor:
Hongbo Guo, Vincent Tropepe, Andrew Emili, Loksum Wong, Jonathan B. Olsen, Jack Greenblatt, Yue Li, Zhaolei Zhang, Amanda Miles, Steven Deimling
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 7, Iss 3, Pp 454-470 (2016)
Stem Cell Reports, Vol 7, Iss 3, Pp 454-470 (2016)
Summary Proliferating progenitor cells undergo changes in competence to give rise to post-mitotic progeny of specialized function. These cell-fate transitions typically involve dynamic regulation of gene expression by histone methyltransferase (HMT)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c3b0ad57d7394bd47193994ed6df05a
https://doi.org/10.1016/j.stemcr.2016.06.012
https://doi.org/10.1016/j.stemcr.2016.06.012
Autor:
Jack Greenblatt, Zhen Yuan Lin, Harshika Jain, Ashley Hutchinson, Bryan Krastins, Mani Ravichandran, Anandi Bhattacharya, Lei Zhao, Alma Seitova, Tin Nguyen, Susanne Gräslund, Marcin Paduch, Anne-Claude Gingras, Gregory Byram, Cheryl H. Arrowsmith, Jeffrey R. Whiteaker, Ruedi Aebersold, Xinghua Guo, Maryann Vogelsang, Evan Dowdell, Aled M. Edwards, Ben C. Collins, Peter Loppnau, Gouri Vadali, Andrew Emili, Sadhna Phanse, Shuye Pu, Nan Zhong, Matthias Gstaiger, Hongbo Guo, Sachdev S. Sidhu, Amanda G. Paulovich, Brett Larsen, Lori Frappier, Jonathan B. Olsen, Shohei Koide, Edyta Marcon, Maria Fenner, Guoqing Zhong, Shane Miersch, Mary F. Lopez, Shoshana J. Wodak, Anthony A. Kossiakoff, Jacob J. Kennedy
Publikováno v:
Nature Methods. 12:725-731
Antibodies are used in multiple cell biology applications, but there are no standardized methods to assess antibody quality-an absence that risks data integrity and reproducibility. We describe a mass spectrometry-based standard operating procedure f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6330746f301feae2a929b19e6632b8ea
https://doi.org/10.1038/nmeth.3472
https://doi.org/10.1038/nmeth.3472
Autor:
Song Wu, Tatiana Shatseva, Dalia Barsyte-Lovejoy, Cheryl H. Arrowsmith, Li Fan, Laura A. Pelletier, Joseph R. Martin, Shawn Chang, Shichong Liu, S. Emtage, David Mendel, Carmen Curtis, Peter Brown, Jonathan B. Olsen, Masoud Vedadi, Abdellah Allali-Hassani, Hannah Nguyen, Stephen Antonysamy, Benjamin A. Garcia, Lisa Hong Chen, Fengling Li, Robert M. Campbell, Feiyu Fred Zhang, Mary M. Mader, Tarun Gheyi
Publikováno v:
The Journal of Biological Chemistry
Background: SMYD2 is a methyltransferase whose role in cancer is poorly understood and is lacking cell-active chemical tools. Results: We describe LLY-507, a small molecule inhibitor of SMYD2. Conclusion: LLY-507 is potent, selective, cell-active, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a8ef4709ee4bdc36f35ae771e3b2396
http://europepmc.org/articles/PMC4447944
http://europepmc.org/articles/PMC4447944
Autor:
Johannes A. Hewel, Anthony A. Kossiakoff, Andrei L. Turinsky, Joyce Li, Hongbo Guo, Zuyao Ni, Mathieu Lupien, Shuye Pu, Marcin Paduch, Sandra Smiley Trimble, Lorelei B. Silverman-Gavrila, Sadhna Phanse, Susanne Gräslund, Edyta Marcon, Rosalind Silverman-Gavrila, Shoshana J. Wodak, Denitza Roudeva, Swneke D. Bailey, Dorothy Yanling Zhao, Peter Young, Guoqing Zhong, Xinghua Guo, Andrew Emili, Jack Greenblatt, Jonathan B. Olsen
Publikováno v:
Cell Reports, Vol 8, Iss 1, Pp 297-310 (2014)
SummaryChromatin regulation is driven by multicomponent protein complexes, which form functional modules. Deciphering the components of these modules and their interactions is central to understanding the molecular pathways these proteins are regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6832b9a119ca3485aa67f01dd270a5b3
http://www.sciencedirect.com/science/article/pii/S2211124714004446
http://www.sciencedirect.com/science/article/pii/S2211124714004446
Autor:
Betty P.K. Poon, Tony Liu, Andrew Emili, Jonathan B. Olsen, Jayesh S. Salvi, Nurussaba Khanam, Janet N.Y. Chan, Kirk Szafranski, Jane D. Wu, Karim Mekhail
Publikováno v:
Developmental Cell. 30(2):177-191
Summary Intergenic transcription within repetitive loci such as the ribosomal DNA (rDNA) repeats of yeast commonly triggers aberrant recombination. Major mechanisms suppressing aberrant rDNA recombination rely on chromatin silencing or RNAPII repress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89278f7860b104346ce444caaa02fbdd