Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Jonathan B Mandell"'
Autor:
David B Huang, Kimberly M Brothers, Jonathan B Mandell, Masashi Taguchi, Peter G Alexander, Dana M Parker, Dean Shinabarger, Chris Pillar, Ian Morrissey, Stephen Hawser, Parviz Ghahramani, Despina Dobbins, Nicholas Pachuda, Ronald Montelaro, Jonathan D Steckbeck, Kenneth L Urish
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0274815 (2022)
The absence of novel antibiotics for drug-resistant and biofilm-associated infections is a global public health crisis. Antimicrobial peptides explored to address this need have encountered significant development challenges associated with size, tox
Externí odkaz:
https://doaj.org/article/59eaa2222fdc466fabfaa701ec609c4a
Autor:
Kimberly M. Brothers, Dana M. Parker, Masashi Taguchi, Dongzhu Ma, Jonathan B. Mandell, Lance L. Thurlow, Venkata C. Byrapogu, Kenneth L. Urish
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Antibiotic stewardship is viewed as having great public health benefit with limited direct benefit to the patient at the time of administration. The objective of our study was to determine if inappropriate administration of antibiotics could
Externí odkaz:
https://doaj.org/article/296df98e54804bc5a6a6e56ead6da5b4
Autor:
Jonathan B. Mandell, Nerone Douglas, Vrutika Ukani, Jan H. Beumer, Jianxia Guo, John Payne, Rebecca Newman, Luigi Mancinelli, Giuseppe Intini, Carolyn J. Anderson, Rebecca Watters, Kurt Weiss
Publikováno v:
Sarcoma, Vol 2022 (2022)
Aldehyde dehydrogenase 1A1 (ALDH) is a cancer stem cell marker highly expressed in metastatic cells. Disulfiram (Dis) is an FDA-approved antialcoholism drug that inhibits ALDH and has been studied as a candidate for drug repurposing in multiple neopl
Externí odkaz:
https://doaj.org/article/5610d5455df849079aaab8917461d7fa
Autor:
Dongzhu Ma, Jonathan B. Mandell, Niles P. Donegan, Ambrose L. Cheung, Wanyan Ma, Scott Rothenberger, Robert M. Q. Shanks, Anthony R. Richardson, Kenneth L. Urish
Publikováno v:
mBio, Vol 10, Iss 6 (2019)
ABSTRACT Staphylococcus aureus is the major organism responsible for surgical implant infections. Antimicrobial treatment of these infections often fails, leading to expensive surgical intervention and increased risk of mortality to the patient. The
Externí odkaz:
https://doaj.org/article/f0c9f228eed34dbda35ad3ab5c193533
Autor:
Jonathan B. Mandell, Berthony Deslouches, Ronald C. Montelaro, Robert M. Q. Shanks, Yohei Doi, Kenneth L. Urish
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Antibiotics are unable to remove biofilms from surgical implants. This high antibiotic tolerance is related to bacterial persisters, a sub-population of bacteria phenotypically tolerant to antibiotics secondary to a reduced metabolic state.
Externí odkaz:
https://doaj.org/article/cb3d0718c264403fae93484e9e97d3c0
Autor:
Pedro L. Rivera, William T. Li, Sumail Bhogal, Jonathan B. Mandell, Rebekah Belayneh, Margaret L. Hankins, John T. Payne, Rebecca J. Watters, Kurt R. Weiss
Publikováno v:
Veterinary and Comparative Oncology.
Autor:
Kyle C. McKenna, Stephen H. Thorne, Dana M. Previte, Michael J. Rizzo, Stephen A.K. Harvey, Kelly M. Beatty, Jonathan B. Mandell, Maxine R. Miller
Mouse Strains from Jackson Laboratories used in experimentation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ca7454bc3cf75147bca35b9c6685f54
https://doi.org/10.1158/2326-6066.22536970.v1
https://doi.org/10.1158/2326-6066.22536970.v1
Autor:
Kyle C. McKenna, Stephen H. Thorne, Dana M. Previte, Michael J. Rizzo, Stephen A.K. Harvey, Kelly M. Beatty, Jonathan B. Mandell, Maxine R. Miller
Ingenuity Canonical Pathways.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ca435f9b367f271bb8218cba4123bbe
https://doi.org/10.1158/2326-6066.22536964
https://doi.org/10.1158/2326-6066.22536964
Autor:
Kyle C. McKenna, Stephen H. Thorne, Dana M. Previte, Michael J. Rizzo, Stephen A.K. Harvey, Kelly M. Beatty, Jonathan B. Mandell, Maxine R. Miller
P815 tumor cell line authentication.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c2368d73d1847fae3bb6fda6c84432
https://doi.org/10.1158/2326-6066.22536973.v1
https://doi.org/10.1158/2326-6066.22536973.v1
Autor:
Kyle C. McKenna, Stephen H. Thorne, Dana M. Previte, Michael J. Rizzo, Stephen A.K. Harvey, Kelly M. Beatty, Jonathan B. Mandell, Maxine R. Miller
IFNγ resistance in E.G7-OVA and P815 tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a17651827593aa7b3da2b8d54b5d1cd
https://doi.org/10.1158/2326-6066.22536982.v1
https://doi.org/10.1158/2326-6066.22536982.v1