Zobrazeno 1 - 10
of 225
pro vyhledávání: '"Jonathan B Angel"'
Autor:
Jonathan B Angel, Ashok Kumar, Michaeline McGuinty, Curtis L Cooper, Juthaporn Cowan, Paul A MacPherson, Sanjay Murthy, Richmond Sy, Michelle Dennehy, Nancy Tremblay, Siddappa N Byrareddy, D William Cameron
Publikováno v:
BMJ Open, Vol 10, Iss 10 (2020)
Introduction Continuous antiretroviral therapy (ART) suppresses HIV plasma viral load (pVL) to very low levels, which allows for some immune recovery. Discontinuation of ART leads to pVL rebound from reservoirs of persistence and latency, and progres
Externí odkaz:
https://doaj.org/article/36d81695384243f18a42b9d91961c5c3
Autor:
Nongnuj Tanphaichitr, Kessiri Kongmanas, Hathairat Kruevaisayawan, Arpornrad Saewu, Clarissa Sugeng, Jason Fernandes, Puneet Souda, Jonathan B Angel, Kym F Faull, R John Aitken, Julian Whitelegge, Daniel Hardy, Trish Berger, Mark Baker
Publikováno v:
Asian Journal of Andrology, Vol 17, Iss 4, Pp 574-582 (2015)
The interaction of sperm with the egg′s extracellular matrix, the zona pellucida (ZP) is the first step of the union between male and female gametes. The molecular mechanisms of this process have been studied for the past six decades with the resul
Externí odkaz:
https://doaj.org/article/e5454d68e34648649f0d8447b52dafdc
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0186823 (2017)
HIV infection causes a profound depletion of gut derived Th17 cells, contributing to loss of mucosal barrier function and an increase in microbial translocation, thus driving systemic immune activation. Despite normalization of circulating CD4+ T cel
Externí odkaz:
https://doaj.org/article/b14cae65b3ae453db6537a1cbb3a8b8c
Autor:
Jean-Guy Baril, Jonathan B Angel, M John Gill, Joseph Gathe, Pedro Cahn, Jean van Wyk, Sharon Walmsley
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148231 (2016)
OBJECTIVE:We reviewed the current literature regarding antiretroviral (ARV)-sparing therapy strategies to determine whether these novel regimens can be considered appropriate alternatives to standard regimens for the initial treatment of ARV-naive pa
Externí odkaz:
https://doaj.org/article/586ec471bcdc4311a06e248026f67dc5
Publikováno v:
Canadian Journal of Infectious Diseases, Vol 12, Iss 3, Pp 157-163 (2001)
Knowledge pertaining to hepatitis C virus (HCV)/human immunodeficiency virus (HIV) co-infection is currently incomplete or conflicting. Several points are well studied, however. Plasma HCV RNA levels are higher in matched HIV-infected people than in
Externí odkaz:
https://doaj.org/article/8201fa2ec4854a998a882589ab7f4719
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28570 (2011)
BackgroundHIV viral load (VL) is currently not part of the criteria for Pneumocystis jirovecii pneumonia (PCP) prophylaxis discontinuation, but suppression of plasma viremia with antiretroviral therapy may allow for discontinuation of PCP prophylaxis
Externí odkaz:
https://doaj.org/article/021f1ae327ae4879ae3053e542ea241c
Autor:
Sekar Natesampillai, Zilin Nie, Nathan W Cummins, Dirk Jochmans, Gary D Bren, Jonathan B Angel, Andrew D Badley
Publikováno v:
PLoS Pathogens, Vol 6, Iss 11, p e1001213 (2010)
In medicine, understanding the pathophysiologic basis of exceptional circumstances has led to an enhanced understanding of biology. We have studied the circumstance of HIV-infected patients in whom antiretroviral therapy results in immunologic benefi
Externí odkaz:
https://doaj.org/article/143cdd7991584c8080240d814977a14a
Autor:
Mona R Loutfy, Trevor A Hart, Saira S Mohammed, DeSheng Su, Edward D Ralph, Sharon L Walmsley, Lena C Soje, Marvelous Muchenje, Anita R Rachlis, Fiona M Smaill, Jonathan B Angel, Janet M Raboud, Michael S Silverman, Wangari E Tharao, Kevin Gough, Mark H Yudin, Ontario HIV Fertility Research Team
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e7925 (2009)
Improvements in life expectancy and quality of life for HIV-positive women coupled with reduced vertical transmission will likely lead numerous HIV-positive women to consider becoming pregnant. In order to clarify the demand, and aid with appropriate
Externí odkaz:
https://doaj.org/article/c05dc47564f648f683cde5c2d377f7b1
Publikováno v:
Canadian Journal of Infectious Diseases and Medical Microbiology, Vol 20, Iss 2, Pp e24-e34 (2009)
BACKGROUND AND OBJECTIVES: A group of five Canadian physicians with significant experience in HIV management was convened. Their goal was to develop guidance specifically for Canadian HIV-treating physicians on the appropriate use of etravirine (TMC1
Externí odkaz:
https://doaj.org/article/4bf3393636064443be1baabca1ff4c01
Autor:
Anita Rachlis, Jonathan B Angel, Marianne Harris, Stephen D Shafran, Rachel Therrien, Cécile Tremblay, Mark A Wainberg
Publikováno v:
Canadian Journal of Infectious Diseases and Medical Microbiology, Vol 20, Iss 3, Pp e67-e80 (2009)
BACKGROUND AND OBJECTIVES: A meeting of a Canadian group with significant experience and knowledge in HIV management, consisting of five physicians, a pharmacist and an AIDS researcher, was convened. Their goal was to develop guidance for Canadian HI
Externí odkaz:
https://doaj.org/article/0653f2f65e0b4f96aa6ea842cabf811d