Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jonathan Axon"'
Autor:
Glenn Mcenroe, Wolfgang Wick, Alison Murphy, Martin Uhl, Ann M. Kapoun, Andrew Lam, Heather K. Webb, Thomas-Toan Tran, Sundeep Dugar, Jonathan Axon, Steffen Aulwurm, Barry Patrick Hart, Linda S. Higgins, Jing Ying Ma, Venkataraman Sriram, Lisa Janssen, Sarvajit Chakravarty, Michael Weller, Darin E. Kizer, Andrew A. Protter, Darren H. Wong, Irene Kerr
Publikováno v:
Neuro-Oncology. 9:259-270
Transforming growth factor-beta (TGF-beta) is a proinvasive and immunosuppressive cytokine that plays a major role in the malignant phenotype of gliomas. One novel strategy of disabling TGF-beta activity in gliomas is to disrupt the signaling cascade
Autor:
Terra D. Haddad, Rebecca Braslau, Marc O. Anderson, Armando Jimenez, Frank Rivera, Jonathan Axon
Publikováno v:
Tetrahedron. 58:5513-5523
The use of acyl hydrazines (hydrazides) as precursors for the stoichiometric generation of acyl radicals is explored. Two classes of substrates are examined: unsubstituted acyl hydrazines and acyl hydrazines substituted with a leaving group (2-nitrob
Publikováno v:
ChemInform. 25
N,N-disubstituted a-(xanthyl)-acetamides with an olefin on one of the substituents undergo cyclisation to a lactam by a radical chain reaction involving transfer of the xanthate group; anilides lead to the corresponding indolones.
Publikováno v:
ChemInform. 26
The diastereoselectivity of radical addition to methyleneoxazolidinones depends on the nature of the addend radical and of the N-protecting group; the reaction provides a convenient enantioselective route to α-amino acids.
Publikováno v:
ChemInform. 31
Publikováno v:
J. Chem. Soc., Chem. Commun.. :549-550
The diastereoselectivity of radical addition to methyleneoxazolidinones depends on the nature of the addend radical and of the N-protecting group; the reaction provides a convenient enantioselective route to α-amino acids.