Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Jonathan A. Silversides"'
Autor:
Neil Cody, MB, ChB, Ian Bradbury, PhD, Ross R. McMullan, MB, ChB, Gerard Quinn, RN, Aisling O’Neill, RN, Kathryn Ward, RN, Justine McCann, RN, Daniel F. McAuley, MD, Jonathan A. Silversides, PhD
Publikováno v:
Critical Care Explorations, Vol 6, Iss 5, p e1094 (2024)
OBJECTIVES:. Near-infrared spectroscopy (NIRS) is a potentially valuable modality to monitor the adequacy of oxygen delivery to the brain and other tissues in critically ill patients, but little is known about the physiologic determinants of NIRS-der
Externí odkaz:
https://doaj.org/article/c9190e9d9223405b8e3a1ad1565ee2e5
Autor:
Jonathan A. Silversides, Ross McMullan, Lydia M. Emerson, Ian Bradbury, Jonathan Bannard-Smith, Tamas Szakmany, John Trinder, Anthony J. Rostron, Paul Johnston, Andrew J. Ferguson, Andrew J. Boyle, Bronagh Blackwood, John C. Marshall, Daniel F. McAuley
Publikováno v:
Silversides, J A, McMullan, R, Emerson, L M, Bradbury, I, Bannard-Smith, J, Szakmany, T, Trinder, T J, Rostron, A J, Johnston, P, Ferguson, A J, Boyle, A J, Blackwood, B, Marshall, J C & McAuley, D F 2021, ' Feasibility of conservative fluid administration and deresuscitation compared with usual care in critical illness: the Role of Active Deresuscitation After Resuscitation-2 (RADAR-2) randomised clinical trial ', Intensive Care Medicine . https://doi.org/10.1007/s00134-021-06596-8
PURPOSE: Fluid overload is common in critical illness and is associated with mortality. This study investigated the feasibility of a randomised trial comparing conservative fluid administration and deresuscitation (active removal of accumulated fluid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f8b962da27751b4579f09f44f4ecbbe
https://doi.org/10.1007/s00134-021-06596-8
https://doi.org/10.1007/s00134-021-06596-8
Autor:
Ewan C. Goligher, Irene Telias, Sarina K. Sahetya, Elias Baedorf-Kassis, Bhakti K. Patel, Nadir Yehya, Jonathan A Silversides, Niall D. Ferguson, Laurent J. Brochard, Patrick R. Lawler, Ryan Zarychanski, Arthur S. Slutsky
Publikováno v:
American journal of respiratory and critical care medicine. 206(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31f32d894d2f3c4c7bd192f5eb8d17a6
https://pubmed.ncbi.nlm.nih.gov/35533404
https://pubmed.ncbi.nlm.nih.gov/35533404
Autor:
Peter McGuigan, Margaret McFarland, Cliona McDowell, Jacqui Thompson, Manu Shankar-Hari, John G. Laffey, Phil Hopkins, Cecilia O'Kane, Gerard F. Curley, Ellen Gorman, Colette Jackson, Gavin D. Perkins, Daniel F. McAuley, Mike Clarke, William Tunnicliffe, Jon Smythe, Jonathan A Silversides, Jamie McFerran, Roisin Boyle, Barry Williams, Anna Krasnodembskaya, Christina Campbell
Publikováno v:
EClinicalMedicine, Vol 41, Iss, Pp 101167-(2021)
EClinicalMedicine
Gorman, E, Shankar-Hari, M, Hopkins, P, Tunnicliffe, W S, Perkins, G D, Silversides, J, McGuigan, P, Krasnodembskaya, A, Jackson, C, Boyle, R, McFerran, J, McDowell, C, Campbell, C, McFarland, M, Smythe, J, Thompson, J, Williams, B, Curley, G, Laffey, J G, Clarke, M, McAuley, D F & O'Kane, C M 2021, ' Repair of acute respiratory distress syndrome by stromal cell administration (REALIST) trial: A phase 1 trial ', EClinicalMedicine-published by THE LANCET, vol. 41, 101167 . https://doi.org/10.1016/j.eclinm.2021.101167
Gorman, E, Shankar-Hari, M, Hopkins, P, Tunnicliffe, W S, Perkins, G D, Silversides, J, McGuigan, P, Krasnodembskaya, A, Jackson, C, Boyle, R, McFerran, J, McDowell, C, Campbell, C, McFarland, M, Smythe, J, Thompson, J, Williams, B, Curley, G, Laffey, J G, Clarke, M, McAuley, D F & O'Kane, C M 2021, ' Repair of acute respiratory distress syndrome by stromal cell administration (REALIST) trial: A phase 1 trial ', EClinicalMedicine, vol. 41 . https://doi.org/10.1016/j.eclinm.2021.101167
EClinicalMedicine
Gorman, E, Shankar-Hari, M, Hopkins, P, Tunnicliffe, W S, Perkins, G D, Silversides, J, McGuigan, P, Krasnodembskaya, A, Jackson, C, Boyle, R, McFerran, J, McDowell, C, Campbell, C, McFarland, M, Smythe, J, Thompson, J, Williams, B, Curley, G, Laffey, J G, Clarke, M, McAuley, D F & O'Kane, C M 2021, ' Repair of acute respiratory distress syndrome by stromal cell administration (REALIST) trial: A phase 1 trial ', EClinicalMedicine-published by THE LANCET, vol. 41, 101167 . https://doi.org/10.1016/j.eclinm.2021.101167
Gorman, E, Shankar-Hari, M, Hopkins, P, Tunnicliffe, W S, Perkins, G D, Silversides, J, McGuigan, P, Krasnodembskaya, A, Jackson, C, Boyle, R, McFerran, J, McDowell, C, Campbell, C, McFarland, M, Smythe, J, Thompson, J, Williams, B, Curley, G, Laffey, J G, Clarke, M, McAuley, D F & O'Kane, C M 2021, ' Repair of acute respiratory distress syndrome by stromal cell administration (REALIST) trial: A phase 1 trial ', EClinicalMedicine, vol. 41 . https://doi.org/10.1016/j.eclinm.2021.101167
Background Mesenchymal stromal cells (MSCs) may be of benefit in acute respiratory distress syndrome (ARDS) due to immunomodulatory, reparative, and antimicrobial actions. ORBCEL-C is a population of CD362 enriched umbilical cord-derived MSCs. The RE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::625418f3f74bca4d6af1f31458d3a812
http://www.sciencedirect.com/science/article/pii/S2589537021004478
http://www.sciencedirect.com/science/article/pii/S2589537021004478
Autor:
Eddy Fan, Andrew Ferguson, John C. Marshall, Bronagh Blackwood, Jonathan A Silversides, Daniel F. McAuley
Publikováno v:
J Intensive Care Soc
Accumulation of a positive fluid balance is common in critically ill patients, and is associated with adverse outcomes, including mortality. However, there are few randomised clinical trials to guide clinicians as to the most appropriate fluid strate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6d2fdcc0f4d028c50e8b1f6c224b07d
https://doi.org/10.1177/1751143719846442
https://doi.org/10.1177/1751143719846442
Autor:
Philip McCall, Brian Lafferty, Prabodh Sasidharan, Adam Glass, B. Shelley, Robbie Lendrum, Jonathan A Silversides
Publikováno v:
Journal of Cardiothoracic and Vascular Anesthesia. 35:S12-S13
Introduction Lung cancer is the leading cause of cancer death in Europe. Surgical resection is often the preferred treatment but is associated with morbidity and mortality. Survival with a meaningful quality of life is important; however, the predict
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::391789e2e12ccbe8eebc0af00e89326b
https://doi.org/10.1053/j.jvca.2021.08.058
https://doi.org/10.1053/j.jvca.2021.08.058
Autor:
Neil MD C, Samuel M Lakey, Sean M McMahon, Megan K Downey, Megan S Duncan, Julie-Anne Hewitt, Calum B Simpson, Martin J Duffy, Rosalind F O’Reilly, Paul Johnston, Jonathan A Silversides, Belfast COVID ICU Group
Background: COVID-19 can result in a severe viral pneumonia, with high reported mortality rates in patients requiring mechanical ventilation. There is controversy as to whether established therapeutic approaches to acute respiratory distress syndrome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35a7435f71dba1cb8072f6b5d804a777
https://doi.org/10.21203/rs.3.rs-58685/v1
https://doi.org/10.21203/rs.3.rs-58685/v1
Autor:
Christina Campbell, Mike Clarke, Ellen Gorman, John G. Laffey, Jacqui Thompson, Phil Hopkins, Gavin D. Perkins, Colette Jackson, Daniel F. McAuley, Jonathan A Silversides, Cliona McDowell, Peter J. McGuigan, Jon Smythe, Gerard F. Curley, Roisin Boyle, Barry Williams, William Tunnicliffe, Jamie McFerran, Margaret McFarland, Manu Shankar-Hari, Cecilia O'Kane
Publikováno v:
Gorman, E, Shankar-Hari, M, Hopkins, P, Tunnicliffe, W S, Perkins, G D, Silversides, J, McGuigan, P, Jackson, C, Boyle, R, McFerran, J, McDowell, C, Campbell, C, McFarland, M, Smythe, J, Thompson, J, Williams, B, Curley, G, Laffey, J G, Clarke, M, O'Kane, C & McAuley, D F 2020, ' Repair of Acute Respiratory Distress Syndrome by Stromal Cell Administration in COVID-19 (REALIST-COVID-19): A structured summary of a study protocol for a randomised, controlled trial ', Trials, vol. 21, no. 1, pp. 462 . https://doi.org/10.1186/s13063-020-04416-w, https://doi.org/10.1186/s13063-020-04416-w
Trials
Trials, Vol 21, Iss 1, Pp 1-3 (2020)
Trials
Trials, Vol 21, Iss 1, Pp 1-3 (2020)
Objectives The primary objective of the study is to assess the safety of a single intravenous infusion of Mesenchymal Stromal Cells (MSCs) in patients with Acute Respiratory Distress Syndrome (ARDS) due to COVID-19. Secondary objectives are to determ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1909d111bf99c230386793115843632e
https://pure.qub.ac.uk/en/publications/repair-of-acute-respiratory-distress-syndrome-by-stromal-cell-administration-in-covid19-realistcovid19-a-structured-summary-of-a-study-protocol-for-a-randomised-controlled-trial(55ff62aa-2ee8-4509-ae9a-bc9b72c12388).html
https://pure.qub.ac.uk/en/publications/repair-of-acute-respiratory-distress-syndrome-by-stromal-cell-administration-in-covid19-realistcovid19-a-structured-summary-of-a-study-protocol-for-a-randomised-controlled-trial(55ff62aa-2ee8-4509-ae9a-bc9b72c12388).html
Publikováno v:
Chest. 157(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::214f9dc0ce22e8ef81b4477cb9411e0d
https://pubmed.ncbi.nlm.nih.gov/31982391
https://pubmed.ncbi.nlm.nih.gov/31982391
Publikováno v:
Intensive Care Medicine. 45:1440-1442
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed8719c243c459f7e6f7ddcea84581c3
https://doi.org/10.1007/s00134-019-05713-y
https://doi.org/10.1007/s00134-019-05713-y