Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jonathan A. Jeyaratnam"'
Publikováno v:
Scopus-Elsevier
Publikováno v:
Journal of Interferon & Cytokine Research. 31:291-298
Interferon-γ pre-exposure inhibits Rac activation by either integrin engagement or platelet-derived growth factor treatment. Interferon-γ does this by inducing expression of the large guanosine triphosphatase (GTPase) mouse guanylate-binding protei
Originally identified by their unusual ability to bind guanosine monophosphate (GMP) nucleotide agarose, the guanylate-binding proteins (GBPs) were used extensively to promote our understanding of interferon-induced gene transcription and as markers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ba8de7048406d16204f069c9f77b55c
https://europepmc.org/articles/PMC3021356/
https://europepmc.org/articles/PMC3021356/
Autor:
Victoria Gorbacheva, Angela F. Messmer-Blust, Sujata Balasubramanian, Deborah J. Vestal, Jonathan A. Jeyaratnam
Publikováno v:
Molecular Biology of the Cell
IFN-γ and mGBP-2 inhibit the spreading of fibroblasts on fibronectin by inhibiting Rac activation. mGBP-2 is incorporated into a protein complex with the catalytic subunit of PI3-K, p110, and inhibits PI3-K activation during spreading. This is a nov
Publikováno v:
Cytokine. 52:14