Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Jonathan A Shortt"'
Autor:
Jonathan A Shortt, Daren C Card, Drew R Schield, Yang Liu, Bo Zhong, Todd A Castoe, Elizabeth J Carlton, David D Pollock
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 1, p e0005292 (2017)
BACKGROUND:In areas where schistosomiasis control programs have been implemented, morbidity and prevalence have been greatly reduced. However, to sustain these reductions and move towards interruption of transmission, new tools for disease surveillan
Externí odkaz:
https://doaj.org/article/ccbeb0a3cf6d42bf9c557d1f251c363e
Autor:
Ying Wang, Shinichi Namba, Esteban Lopera, Sini Kerminen, Kristin Tsuo, Kristi Läll, Masahiro Kanai, Wei Zhou, Kuan-Han Wu, Marie-Julie Favé, Laxmi Bhatta, Philip Awadalla, Ben Brumpton, Patrick Deelen, Kristian Hveem, Valeria Lo Faro, Reedik Mägi, Yoshinori Murakami, Serena Sanna, Jordan W. Smoller, Jasmina Uzunovic, Brooke N. Wolford, Cristen Willer, Eric R. Gamazon, Nancy J. Cox, Ida Surakka, Yukinori Okada, Alicia R. Martin, Jibril Hirbo, Kuan-Han H. Wu, Humaira Rasheed, Jibril B. Hirbo, Arjun Bhattacharya, Huiling Zhao, Esteban A. Lopera-Maya, Sinéad B. Chapman, Juha Karjalainen, Mitja Kurki, Maasha Mutaamba, Juulia J. Partanen, Ben M. Brumpton, Sameer Chavan, Tzu-Ting Chen, Michelle Daya, Yi Ding, Yen-Chen A. Feng, Christopher R. Gignoux, Sarah E. Graham, Whitney E. Hornsby, Nathan Ingold, Ruth Johnson, Triin Laisk, Kuang Lin, Jun Lv, Iona Y. Millwood, Priit Palta, Anita Pandit, Michael H. Preuss, Unnur Thorsteinsdottir, Matthew Zawistowski, Xue Zhong, Archie Campbell, Kristy Crooks, Geertruida H. de Bock, Nicholas J. Douville, Sarah Finer, Lars G. Fritsche, Christopher J. Griffiths, Yu Guo, Karen A. Hunt, Takahiro Konuma, Riccardo E. Marioni, Jansonius Nomdo, Snehal Patil, Nicholas Rafaels, Anne Richmond, Jonathan A. Shortt, Peter Straub, Ran Tao, Brett Vanderwerff, Kathleen C. Barnes, Marike Boezen, Zhengming Chen, Chia-Yen Chen, Judy Cho, George Davey Smith, Hilary K. Finucane, Lude Franke, Andrea Ganna, Tom R. Gaunt, Tian Ge, Hailiang Huang, Jennifer Huffman, Jukka T. Koskela, Clara Lajonchere, Matthew H. Law, Liming Li, Cecilia M. Lindgren, Ruth J.F. Loos, Stuart MacGregor, Koichi Matsuda, Catherine M. Olsen, David J. Porteous, Jordan A. Shavit, Harold Snieder, Richard C. Trembath, Judith M. Vonk, David Whiteman, Stephen J. Wicks, Cisca Wijmenga, John Wright, Jie Zheng, Xiang Zhou, Michael Boehnke, Daniel H. Geschwind, Caroline Hayward, Eimear E. Kenny, Yen-Feng Lin, Hilary C. Martin, Sarah E. Medland, Aarno V. Palotie, Bogdan Pasaniuc, Kari Stefansson, David A. van Heel, Robin G. Walters, Sebastian Zöllner, Cristen J. Willer, Mark J. Daly, Benjamin M. Neale
Publikováno v:
Cell Genomics, Vol 3, Iss 1, Pp 100241- (2023)
Summary: Polygenic risk scores (PRSs) have been widely explored in precision medicine. However, few studies have thoroughly investigated their best practices in global populations across different diseases. We here utilized data from Global Biobank M
Externí odkaz:
https://doaj.org/article/ab70f310dfdd4e7dbc3dc7fc2ba9b939
Autor:
Aaron Lazorwitz, Christina L. Aquilante, Jonathan A. Shortt, Jeanelle Sheeder, Stephanie Teal, Christopher R. Gignoux
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 5, Pp 1713-1718 (2021)
Abstract To compare etonogestrel pharmacokinetic and pharmacodynamic outcomes by both self‐reported race/ethnicity and genetically determined ancestry among contraceptive implant users. We conducted a secondary analysis of our parent pharmacogenomi
Externí odkaz:
https://doaj.org/article/b24411632bc946c4b79cce7d2e001566
Autor:
Jonathan A. Shortt, Laura E. Timm, Nicole R. Hales, Zachary L. Nikolakis, Drew R. Schield, Blair W. Perry, Yang Liu, Bo Zhong, Todd A. Castoe, Elizabeth J. Carlton, David D. Pollock
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Schistosomiasis persists in Asian regions despite aggressive elimination measures. To identify factors enabling continued parasite transmission, we performed reduced representation genome sequencing on Schistosoma japonicum miracidia collect
Externí odkaz:
https://doaj.org/article/88ac916eacf44902a474faab6be79854
Publikováno v:
Mobile DNA, Vol 11, Iss 1, Pp 1-12 (2020)
Abstract Background Previously, 3% of the human genome has been annotated as simple sequence repeats (SSRs), similar to the proportion annotated as protein coding. The origin of much of the genome is not well annotated, however, and some of the unide
Externí odkaz:
https://doaj.org/article/92bccca6c8f048ed8070965e04a7aeed
Autor:
Giulia I. M. Pasquesi, Richard H. Adams, Daren C. Card, Drew R. Schield, Andrew B. Corbin, Blair W. Perry, Jacobo Reyes-Velasco, Robert P. Ruggiero, Michael W. Vandewege, Jonathan A. Shortt, Todd A. Castoe
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Large-scale patterns of genomic repeat element evolution have been studied mainly in birds and mammals. Here, the authors analyze the genomes of over 60 squamate reptiles and show high variation in repeat elements compared to mammals and birds, and p
Externí odkaz:
https://doaj.org/article/8127123f3f9445269e6fca03f4205157
Autor:
Nikita Pozdeyev, Manjiri Dighe, Martin Barrio, Christopher Raeburn, Harry Smith, Matthew Fisher, Sameer Chavan, Nicholas Rafaels, Jonathan A. Shortt, Meng Lin, Michael G. Leu, Toshimasa Clark, Carrie Marshall, Bryan R. Haugen, Devika Subramanian, Regeneron Genetics Center, Kristy Crooks, Christopher Gignoux, Trevor Cohen
Evaluating thyroid nodules to rule out malignancy is a very common clinical task. Image-based clinical and machine learning risk stratification schemas rely on the presence of thyroid nodule high-risk sonographic features. However, this approach is l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c854fe7553844c314bc0efc1182c4cc
https://doi.org/10.1101/2023.04.11.23288041
https://doi.org/10.1101/2023.04.11.23288041
Autor:
Amanda N. Brice, Lauren A. Vanderlinden, Katie M. Marker, David Mayer, Meng Lin, Nicholas Rafaels, Jonathan A. Shortt, Alex Romero, Jan T. Lowery, Christopher R. Gignoux, Randi K. Johnson
Publikováno v:
International Journal of Environmental Research and Public Health
Volume 20
Issue 3
Pages: 2368
Volume 20
Issue 3
Pages: 2368
Over 6.37 million people have died from COVID-19 worldwide, but factors influencing COVID-19-related mortality remain understudied. We aimed to describe and identify risk factors for COVID-19 mortality in the Colorado Center for Personalized Medicine
Autor:
Masahiro Kanai, Roy Elzur, Wei Zhou, Mark J. Daly, Hilary K. Finucane, Kuan-Han H. Wu, Humaira Rasheed, Kristin Tsuo, Jibril B. Hirbo, Ying Wang, Arjun Bhattacharya, Huiling Zhao, Shinichi Namba, Ida Surakka, Brooke N. Wolford, Valeria Lo Faro, Esteban A. Lopera-Maya, Kristi Läll, Marie-Julie Favé, Juulia J. Partanen, Sinéad B. Chapman, Juha Karjalainen, Mitja Kurki, Mutaamba Maasha, Ben M. Brumpton, Sameer Chavan, Tzu-Ting Chen, Michelle Daya, Yi Ding, Yen-Chen A. Feng, Lindsay A. Guare, Christopher R. Gignoux, Sarah E. Graham, Whitney E. Hornsby, Nathan Ingold, Said I. Ismail, Ruth Johnson, Triin Laisk, Kuang Lin, Jun Lv, Iona Y. Millwood, Sonia Moreno-Grau, Kisung Nam, Priit Palta, Anita Pandit, Michael H. Preuss, Chadi Saad, Shefali Setia-Verma, Unnur Thorsteinsdottir, Jasmina Uzunovic, Anurag Verma, Matthew Zawistowski, Xue Zhong, Nahla Afifi, Kawthar M. Al-Dabhani, Asma Al Thani, Yuki Bradford, Archie Campbell, Kristy Crooks, Geertruida H. de Bock, Scott M. Damrauer, Nicholas J. Douville, Sarah Finer, Lars G. Fritsche, Eleni Fthenou, Gilberto Gonzalez-Arroyo, Christopher J. Griffiths, Yu Guo, Karen A. Hunt, Alexander Ioannidis, Nomdo M. Jansonius, Takahiro Konuma, Ming Ta Michael Lee, Arturo Lopez-Pineda, Yuta Matsuda, Riccardo E. Marioni, Babak Moatamed, Marco A. Nava-Aguilar, Kensuke Numakura, Snehal Patil, Nicholas Rafaels, Anne Richmond, Agustin Rojas-Muñoz, Jonathan A. Shortt, Peter Straub, Ran Tao, Brett Vanderwerff, Manvi Vernekar, Yogasudha Veturi, Kathleen C. Barnes, Marike Boezen, Zhengming Chen, Chia-Yen Chen, Judy Cho, George Davey Smith, Lude Franke, Eric R. Gamazon, Andrea Ganna, Tom R. Gaunt, Tian Ge, Hailiang Huang, Jennifer Huffman, Nicholas Katsanis, Jukka T. Koskela, Clara Lajonchere, Matthew H. Law, Liming Li, Cecilia M. Lindgren, Ruth J.F. Loos, Stuart MacGregor, Koichi Matsuda, Catherine M. Olsen, David J. Porteous, Jordan A. Shavit, Harold Snieder, Tomohiro Takano, Richard C. Trembath, Judith M. Vonk, David C. Whiteman, Stephen J. Wicks, Cisca Wijmenga, John Wright, Jie Zheng, Xiang Zhou, Philip Awadalla, Michael Boehnke, Carlos D. Bustamante, Nancy J. Cox, Segun Fatumo, Daniel H. Geschwind, Caroline Hayward, Kristian Hveem, Eimear E. Kenny, Seunggeun Lee, Yen-Feng Lin, Hamdi Mbarek, Reedik Mägi, Hilary C. Martin, Sarah E. Medland, Yukinori Okada, Aarno V. Palotie, Bogdan Pasaniuc, Daniel J. Rader, Marylyn D. Ritchie, Serena Sanna, Jordan W. Smoller, Kari Stefansson, David A. van Heel, Robin G. Walters, Sebastian Zöllner, null Biobank of the Americas, null Biobank Japan Project, null BioMe, null BioVU, null CanPath - Ontario Health Study, null China Kadoorie Biobank Collaborative Group, null Colorado Center for Personalized Medicine, null deCODE Genetics, null Estonian Biobank, FinnGen, null Generation Scotland, null Genes & Health Research Team, null LifeLines, null Mass General Brigham Biobank, null Michigan Genomics Initiative, null National Biobank of Korea, null Penn Medicine BioBank, null Qatar Biobank, null The Qskin Sun and Health Study, null Taiwan Biobank, null The Hunt Study, null Ucla Atlas Community Health Initiative, null Uganda Genome Resource, null Uk Biobank, Alicia R. Martin, Cristen J. Willer, Benjamin M. Neale
Funding Information: We acknowledge all the participants and researchers of the 23 biobanks that have contributed to the GBMI. Biobank-specific acknowledgments are included in the Data S3 . We thank H. Huang, A.R. Martin, B.M. Neale, Y. Okada, K. Tsu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26876d7b7cfd7d51f3112e7e7afb5a3a
http://hdl.handle.net/10138/355361
http://hdl.handle.net/10138/355361
Autor:
Laura K Wiley, Jonathan A Shortt, Emily R Roberts, Jan Lowery, Elizabeth Kudron, Meng Lin, David A Mayer, Melissa P Wilson, Tonya M Brunetti, Sameer Chavan, Tzu L Phang, Nikita Pozdeyev, Joseph Lesny, Stephen J Wicks, Ethan Moore, Joshua L Morgenstern, Alanna N Roff, Elise L Shalowitz, Adrian Stewart, Cole Williams, Michelle N Edelmann, Madelyne Hull, J. Tacker Patton, Lisen Axell, Lisa Ku, Yee Ming Lee, Jean Jirikowic, Anna Tanaka, Emily Todd, Sarah White, Brett Peterson, Emily Hearst, Richard Zane, Casey S Greene, Rasika Mathias, Marilyn Coors, Matthew RG Taylor, Debashis Ghosh, Michael G Kahn, Ian M Brooks, Christina L Aquilante, David Kao, Nicholas Rafaels, Kristy Crooks, Steve Hess, Kathleen C Barnes, Christopher R Gignoux
Precision medicine initiatives across the globe have led to a revolution of repositories linking large-scale genomic data with electronic health records, enabling genomic analyses across the entire phenome. Many of these initiatives focus solely on r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8471beca0a0725070c7875392f2fbde9
https://doi.org/10.1101/2022.06.09.22276222
https://doi.org/10.1101/2022.06.09.22276222