Zobrazeno 1 - 10
of 178
pro vyhledávání: '"Jonathan A McCullers"'
Autor:
Angeline E Rodriguez, Christopher Bogart, Christopher M Gilbert, Jonathan A McCullers, Amber M Smith, Thirumala-Devi Kanneganti, Christopher R Lupfer
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212236 (2019)
Viral-bacterial coinfections, such as with influenza A virus and Streptococcus pneumoniae (S.p.), are known to cause severe pneumonia. It is well known that the host response has an important role in disease. Interleukin-1β (IL-1β) is an important
Externí odkaz:
https://doaj.org/article/dd5b7f25f6034424807b638b6ebc2cfa
Autor:
Jason W Rosch, Amy R Iverson, Jessica Humann, Beth Mann, Geli Gao, Peter Vogel, Michael Mina, Kyle A Murrah, Antonia C Perez, W Edward Swords, Elaine I Tuomanen, Jonathan A McCullers
Publikováno v:
EMBO Molecular Medicine, Vol 6, Iss 1, Pp 141-154 (2013)
Abstract Acute otitis media (AOM) caused by Streptococcus pneumoniae remains one of the most common infectious diseases worldwide despite widespread vaccination. A major limitation of the currently licensed pneumococcal vaccines is the lack of effica
Externí odkaz:
https://doaj.org/article/de0ad90ef07e4977a24c94db68f79a84
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e111603 (2014)
PB1-F2 protein, expressed from an alternative reading frame of most influenza A virus (IAV) PB1 segments, may possess specific residues associated with enhanced inflammation (L62, R75, R79, and L82) and cytotoxicity (I68, L69, and V70). These residue
Externí odkaz:
https://doaj.org/article/9e4b902289c44f7b9cb7a3f03e9faf43
Autor:
Amber M Smith, Frederick R Adler, Ruy M Ribeiro, Ryan N Gutenkunst, Julie L McAuley, Jonathan A McCullers, Alan S Perelson
Publikováno v:
PLoS Pathogens, Vol 9, Iss 3, p e1003238 (2013)
Secondary bacterial infections are a leading cause of illness and death during epidemic and pandemic influenza. Experimental studies suggest a lethal synergism between influenza and certain bacteria, particularly Streptococcus pneumoniae, but the pre
Externí odkaz:
https://doaj.org/article/80bd0af2c13d47d994bd55b47d3c9a6a
Autor:
Amber M Smith, Frederick R Adler, Julie L McAuley, Ryan N Gutenkunst, Ruy M Ribeiro, Jonathan A McCullers, Alan S Perelson
Publikováno v:
PLoS Computational Biology, Vol 7, Iss 2, p e1001081 (2011)
Relatively little is known about the viral factors contributing to the lethality of the 1918 pandemic, although its unparalleled virulence was likely due in part to the newly discovered PB1-F2 protein. This protein, while unnecessary for replication,
Externí odkaz:
https://doaj.org/article/4b22962761f448a1bf1fbadf1a1cf4b9
Autor:
Julie L McAuley, Jerry E Chipuk, Kelli L Boyd, Nick Van De Velde, Douglas R Green, Jonathan A McCullers
Publikováno v:
PLoS Pathogens, Vol 6, Iss 7, p e1001014 (2010)
With the recent emergence of a novel pandemic strain, there is presently intense interest in understanding the molecular signatures of virulence of influenza viruses. PB1-F2 proteins from epidemiologically important influenza A virus strains were stu
Externí odkaz:
https://doaj.org/article/9ae2944b0c704cd4b3cd641fb86dddaf
Publikováno v:
PLoS Pathogens, Vol 3, Iss 3, p e28 (2007)
Externí odkaz:
https://doaj.org/article/f7e12463a46d4be48328fadb805519aa
Publikováno v:
PLoS Medicine, Vol 3, Iss 9, p e375 (2006)
Externí odkaz:
https://doaj.org/article/1ab780ef4ffc4c929a4232b27e51a20c
Publikováno v:
Journal of the Pediatric Infectious Diseases Society. 11:274-282
Background Diagnostic testing for bacterial etiology of community-acquired pneumonia (CAP) is insensitive. Induced sputum (IS) is an attractive option for the evaluation of the lower respiratory tract. Methods Children aged 0-18 years with CAP were e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a783dc6e35f1c7fcc1d2cb43ce72c0f
https://doi.org/10.1093/jpids/piac014
https://doi.org/10.1093/jpids/piac014
Autor:
Sandra R. Arnold, Seema Jain, David Dansie, Herman Kan, Derek J. Williams, Krow Ampofo, Evan J. Anderson, Carlos G. Grijalva, Anna M. Bramley, Andrew T. Pavia, Kathryn M. Edwards, Vikki G. Nolan, Jonathan A. McCullers, Robert A. Kaufman
Publikováno v:
The Journal of Pediatrics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b77fad547d619f4d6b6e2fa9f956a2e
https://doi.org/10.1016/j.jpeds.2023.01.010
https://doi.org/10.1016/j.jpeds.2023.01.010