Zobrazeno 1 - 10
of 583
pro vyhledávání: '"Jonathan A Coles"'
Publikováno v:
Annals of Intensive Care, Vol 14, Iss 1, Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/abc5ea2323024c4eb2fa022b6d9a8f54
Autor:
Annerixt Gribnau, Mark L. van Zuylen, Jonathan P. Coles, Mark P. Plummer, Henning Hermanns, Jeroen Hermanides
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 2513 (2024)
Traumatic brain injury (TBI) is a major public health concern with significant consequences across various domains. Following the primary event, secondary injuries compound the outcome after TBI, with disrupted glucose metabolism emerging as a releva
Externí odkaz:
https://doaj.org/article/1da8f0d9b5ea4f46a4a15ce9881f16f2
Autor:
Tilak Das, Ruben Dammers, Emily Feilding, Vanessa Elliott, Laurence Glancz, Robert Grange, Peter Hartley, Felix Gooding, Dana Holl, Taj Hassan, Richard Knight, Julia Jones, Thais Minett, Val Luoma, George Peck, Stephen Novak, Ahmed-Ramadan Sadek, Shvaita Ralhan, Davina Richardson, Jennifer Ramshaw, Francoise Sheppard, Rebecca Rous, Katie Sheehan, David Shipway, Christelle Smit, Navneet Singh, Rhonda Sturley, Martin Smith, William Thomas, Michael Swart, Anthony Figaji, Crispin Weidmann, James Uprichard, David K Menon, Vickie Yeardley, Peter J Hutchinson, Paul M Brennan, Akbar Ansari, Christopher Corbett, Marilise Galea, Natalie Gray, Conor Gillespie, Harry Mee, Mary Dixon-Woods, Daniel J Stubbs, Thomas H Bashford, Benjamin M Davies, Diedrik Bulters, Philip Braude, Sophie Camp, Jonathan P Coles, Georgina Carr, Judith Dinsmore, Jugdeep Dhesi, Nicholas R Evans, Ellie Edlmann, Fiona Lecky, Emily Foster, Alexis Joannides, Angelos Kolias, Mike Nathanson, Iain Moppett, Nicola Owen, Virginia Newcombe, Amy Proffitt, Lisa Peterman, Sally R Wilson, Charlotte Skiterall, Ardalan Zolnourian, Peter Whitfield, Nick Borg, Meriem Amarouche, Charlotte Brown
Publikováno v:
Wellcome Open Research, Vol 8 (2023)
Introduction: A common neurosurgical condition, chronic subdural haematoma (cSDH) typically affects older people with other underlying health conditions. The care of this potentially vulnerable cohort is often, however, fragmented and suboptimal. In
Externí odkaz:
https://doaj.org/article/2915f8e6aaf94e3db55636303579cca2
Autor:
Xiaoyu Yang, Benjamin M. Davies, Jonathan P. Coles, David K. Menon, Daniel J. Stubbs, Aref-Ali Gharooni, Wunna Aung, Michelle L. Starkey, Douglas Hay, Fahim Anwar, Ivan S. Timofeev, Adel Helmy, Virginia F.J. Newcombe, Mark R.N. Kotter, Peter J.A. Hutchinson
Publikováno v:
Brain and Spine, Vol 3, Iss , Pp 102702- (2023)
Introduction: The epidemiology and prognosis of the isolated traumatic brain injury (TBI) and spinal cord injury (SCI) are well studied. However, the knowledge of the impact of concurrent neurotrauma is very limited. Research questions: To characteri
Externí odkaz:
https://doaj.org/article/2df8f66981ad416c8c1c08afdff00077
Autor:
Teerawit Audshasai, Jonathan A. Coles, Stavros Panagiotou, Shadia Khandaker, Hannah E. Scales, Morten Kjos, Murielle Baltazar, Julie Vignau, James M. Brewer, Aras Kadioglu, Marie Yang
Publikováno v:
mBio, Vol 13, Iss 4 (2022)
ABSTRACT The entry routes and translocation mechanisms of microorganisms or particulate materials into the central nervous system remain obscure We report here that Streptococcus pneumoniae (pneumococcus), or polystyrene microspheres of similar size,
Externí odkaz:
https://doaj.org/article/a69df22b4cba440db00265f14bfb2761
Autor:
Elijah Mak, Anastasia Bickerton, Concepcion Padilla, Madeleine J. Walpert, Tiina Annus, Liam R. Wilson, Young T. Hong, Tim D. Fryer, Jonathan P. Coles, Franklin I. Aigbirhio, Bradley T. Christian, Benjamin L. Handen, William E. Klunk, David K. Menon, Peter J. Nestor, Shahid H. Zaman, Anthony J. Holland
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 11, Iss 1, Pp 654-658 (2019)
Abstract Introduction Comorbid Alzheimer disease pathologies are frequently found in people with Down syndrome (DS). We report a deep phenotyping study undertaken over 7 years in a participant with DS who was nondemented at baseline but developed dem
Externí odkaz:
https://doaj.org/article/cf9f58123da64fa0b0dfa7a35446bd59
Publikováno v:
The Open Journal of Astrophysics, Vol 4 (2021)
We study the radial and azimuthal mass distribution of the lensing galaxy in WFI2033-4723. Mindful of the fact that modeling results depend on modeling assumptions, we examine two very different recent models: simply parametrized (SP) models from the
Externí odkaz:
https://doaj.org/article/1aaac99a893a4fa98289b6fd20f4d53c
Autor:
Marian Galovic, Kjell Erlandsson, Tim D. Fryer, Young T. Hong, Roido Manavaki, Hasan Sari, Sarah Chetcuti, Benjamin A. Thomas, Martin Fisher, Selena Sephton, Roberto Canales, Joseph J Russell, Kerstin Sander, Erik Årstad, Franklin I. Aigbirhio, Ashley M. Groves, John S. Duncan, Kris Thielemans, Brian F. Hutton, Jonathan P. Coles, Matthias J. Koepp
Publikováno v:
NeuroImage, Vol 237, Iss , Pp 118194- (2021)
Blood-based kinetic analysis of PET data relies on an accurate estimate of the arterial plasma input function (PIF). An alternative to invasive measurements from arterial sampling is an image-derived input function (IDIF). However, an IDIF provides t
Externí odkaz:
https://doaj.org/article/57d2611920154aa588abda4ba324fa91
Autor:
Jeroen Hermanides, Mark P. Plummer, Mark Finnis, Adam M. Deane, Jonathan P. Coles, David K. Menon
Publikováno v:
Critical Care, Vol 22, Iss 1, Pp 1-11 (2018)
Abstract Background Optimal glycaemic targets in traumatic brain injury (TBI) remain unclear. We performed a systematic review and meta-analysis of randomised controlled trials (RCTs) comparing intensive with conventional glycaemic control in TBI req
Externí odkaz:
https://doaj.org/article/f2d3397ce5f943669246af0a2a3854f2
Autor:
Stephanie S.G. Brown, Elijah Mak, Isabel Clare, Monika Grigorova, Jessica Beresford-Webb, Madeline Walpert, Elizabeth Jones, Young T. Hong, Tim D. Fryer, Jonathan P. Coles, Franklin I. Aigbirhio, Dana Tudorascu, Annie Cohen, Bradley T. Christian, Benjamin L. Handen, William E. Klunk, David K. Menon, Peter J. Nestor, Anthony J. Holland, Shahid H. Zaman
Publikováno v:
Neurobiology of Aging. 115:112-121
Down's syndrome results from trisomy of chromosome 21, a genetic change which also confers a probable 100% risk for the development of Alzheimer's disease neuropathology (amyloid plaque and neurofibrillary tangle formation) in later life. We aimed to