Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jonathan A Chatzkel"'
Autor:
Lisa Scarton, Tarah Nelson, Ara Jo, LaToya J. O’Neal, Yingwei Yao, Shavondra Huggins, Anatolia B. Legaspi, Mariah J. McClaren, Jake S. Cabassa, Joan M. Burgos Melendez, Juan M. Munoz‐Pena, Merry J. Markham, Martina C. Murphy, Jonathan A. Chatzkel, Sherise Rogers, Thomas J. George
Publikováno v:
Cancer Medicine, Vol 12, Iss 11, Pp 12874-12880 (2023)
Abstract Background Undiagnosed Type 2 diabetes (T2D) has been associated with advanced stage cancer at diagnosis, higher mortality, and lower long‐term all‐cause survival. This was a RCT pilot study to examine the feasibility of a nurse‐led T2
Externí odkaz:
https://doaj.org/article/49d82266d8a4424c9595e8650f00f575
Autor:
Brian H Ramnaraign, Ji-Hyun Lee, Azka Ali, Sherise C Rogers, Jesus C Fabregas, Ryan M Thomas, Carmen J Allegra, Ilyas Sahin, David L DeRemer, Thomas J George, Jonathan A Chatzkel
Publikováno v:
Future Oncology. 18:3815-3822
Immune checkpoint inhibitor therapy represents a significant advance in cancer care. The interaction between PD-1 and PD-L1 induces immune tolerance and the inhibition of this interaction is an effective treatment strategy for numerous malignancies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::befb38bcf4f60c643c910a11decc276d
https://doi.org/10.2217/fon-2022-0392
https://doi.org/10.2217/fon-2022-0392
Autor:
Thomas J. George, Dennie Jones, Zeina Al-Mansour, Jonathan Alexander Chatzkel, Brian Hemendra Ramnaraign, David L. DeRemer, Sherise C. Rogers
Publikováno v:
JCO Oncology Practice. 17:240-245
Patients with autoimmune disorders, multiple comorbidities, poor performance status, advanced age, and infection with SARS-CoV-2 (COVID-19) each represent unique subgroups of patients with cancer to whom little is known of the effects, benefits, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::342286a531f76dc8c26c826384e5f1aa
https://doi.org/10.1200/op.20.00996
https://doi.org/10.1200/op.20.00996
Autor:
Jonathan Alexander Chatzkel, Ji-Hyun Lee, azka ali, Carmen Joseph Allegra, Paul Crispen, Dennie V. Jones, Padraic O'Malley, Thomas J. George, Brian Hemendra Ramnaraign
Publikováno v:
Journal of Clinical Oncology. 41:TPS293-TPS293
TPS208 Background: Castrate resistant prostate cancer (CRPC) is an immunologically cold tumor, with a 5% response rate reported to the PD-L1 inhibitor pembrolizumab. VEGF secreted by tumors may play a key role in hindering the anti-tumor immune respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ac7ca96eb51989ee9554b8d48778382
https://doi.org/10.1200/jco.2023.41.6_suppl.tps293
https://doi.org/10.1200/jco.2023.41.6_suppl.tps293
Autor:
Lisa Scarton, Tarah Nelson, Yingwei Yao, Shavondra Huggins, Ara Jo, LaToya J. O'Neal, Thomas J. George, Juan M. Munoz-Pena, Merry J. Markham, Martina C. Murphy, Jonathan A. Chatzkel, Sherise Rogers
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 32:B130-B130
Background: Each year 1.4 million adults are diagnosed with diabetes, and in 2022 more than 1.9 million Americans will be diagnosed with cancer. There is a strong link between type 2 diabetes (T2D) and several types of cancer, and both conditions are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83cc90fdfc36deb2e1326303145db997
https://doi.org/10.1158/1538-7755.disp22-b130
https://doi.org/10.1158/1538-7755.disp22-b130
Autor:
Hiroko Miyagi, Elizabeth Kwenda, Brian H. Ramnaraign, Jonathan A. Chatzkel, Wayne G. Brisbane, Padraic O’Malley, Paul L. Crispen
Publikováno v:
Cancers. 15:168
Muscle-invasive bladder cancer is a life-threatening disease best managed with multimodal therapy. Neoadjuvant chemotherapy prior to cystectomy significantly improves survival with the greatest benefit noted in patients with a complete pathologic res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5476e9fac2aed6d57efe6700be344829
https://doi.org/10.3390/cancers15010168
https://doi.org/10.3390/cancers15010168
Autor:
Thomas J. George, Ji-Hyun Lee, Peter Joel Hosein, David L. DeRemer, Jonathan Alexander Chatzkel, Brian Hemendra Ramnaraign, Sherise C. Rogers, Merry Jennifer Markham, Karen Colleen Daily, Nkiruka Ezenwajiaku, Derek Li, Martina Cathryn Murphy, Aaron J Franke, Stephen Staal, Julia Lee Close, Dennie V. Jones, Carmen Joseph Allegra
Publikováno v:
Journal of Clinical Oncology. 40:3122-3122
3122 Background: BRCA1-Associated Protein 1 (BAP1) acts as a tumor suppressor and critical regulator of the cell cycle and DNA damage response (DDR). PARP inhibitors (PARPi) demonstrate synthetic lethality in BAP1 mutant (mBAP1) preclinical models, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::368fa23879f1c133a12e26d76c269856
https://doi.org/10.1200/jco.2022.40.16_suppl.3122
https://doi.org/10.1200/jco.2022.40.16_suppl.3122
Autor:
Brian Hemendra Ramnaraign, Ji-Hyun Lee, azka ali, Sherise C. Rogers, Jesus C. Fabregas, Ryan M. Thomas, Carmen Joseph Allegra, Ilyas Sahin, David L. DeRemer, Thomas J. George, Jonathan Alexander Chatzkel
Publikováno v:
Journal of Clinical Oncology. 40:TPS491-TPS491
TPS491 Background: Checkpoint inhibition (CPI) represents a significant advance in cancer care however it is not effective in the treatment of several immunologically cold tumors including pancreatic, gallbladder, and biliary cancers where checkpoint
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de01159a1ba3f5aecd6b7ffa40b97c11
https://doi.org/10.1200/jco.2022.40.4_suppl.tps491
https://doi.org/10.1200/jco.2022.40.4_suppl.tps491
Autor:
Jun-Min Zhou, Ghassan El-Haddad, Jonathan Alexander Chatzkel, Young Chul Kim, Jesse Mocha, Johnna Smith, Jingsong Zhang
Publikováno v:
Future Science OA
Aim: Radium-223 improves overall survival in patients with metastatic castration-resistant prostate cancer to the bone. Radium-223 causes double-strand DNA breaks and produces γH2AX, a potential biomarker for response. We examined the feasibility of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4133ad0d0f6b9aa6ccf17a0384aed430
http://europepmc.org/articles/PMC6920735
http://europepmc.org/articles/PMC6920735
Autor:
Myung-Chul Kim, Nicholas Borcherding, Sara M. Falzarano, Zeng Jin, Weizhou Zhang, Jonathan Alexander Chatzkel, Ryan Kolb
Publikováno v:
Cancers, Vol 13, Iss 5856, p 5856 (2021)
Cancers
Cancers
Simple Summary Clear cell renal cell carcinomas (ccRCC) have several distinct immunological features, including a high degree of immune infiltration and relatively low mutational burdens, the resistance to cytotoxic chemotherapy, and relative sensiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17d14908d376ef3a50ba73b6b2318346
https://doi.org/10.3390/cancers13225856
https://doi.org/10.3390/cancers13225856