Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Jonathan A, Terrett"'
Autor:
Luis Gamboa, Mohammed G. Ghonime, Demetrios Kalaitzidis, Robert Chain, Daniel Hostetter, Brigid McEwan, Meghna Kuppuraju, Zinkal Padalia, Jonathan Alexander Terrett
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundCD33 is the most consistently expressed antigen in AML, with high levels and homogeneous expression observed in malignant AML cells from most patients, including those with relapsed disease. Normal myelomonocytic cell lineages and a percent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f63e010c4536eaabc1f8022ae004f1e6
https://doi.org/10.1136/jitc-2021-sitc2021.133
https://doi.org/10.1136/jitc-2021-sitc2021.133
Autor:
Andrew Dunn, Sarah Spencer, Mary-Lee Dequeant, Pooja Keerthipati, Jason Gary Sagert, Brigid McEwan, Zinkal Padalia, Paul Tetteh, Thao Nguyen, Jonathan Alexander Terrett, Nicolette Lee, Daniel R. Henderson, Sushant Karnik, Henia Dar, Hui Yu, Ashley Porras, Demetri Kalaitzidis
Publikováno v:
Cancer Research. 81:1537-1537
CD70 and its ligand, CD27, have been described as both activating and suppressing for different cell types including B and T cells. There has been speculation that the CD70/CD27 axis can act in a checkpoint or co-stimulatory manner in certain immuno-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9870f25bc48f46191bfbbed1da9a95ed
https://doi.org/10.1158/1538-7445.am2021-1537
https://doi.org/10.1158/1538-7445.am2021-1537
Autor:
Meghna Kuppuraju, Konstantinos Karagiannis, Brigid McEwan, Sushant Karnik, Mary-Lee Dequeant, Zinkal Padalia, Demetrios Kalaitzidis, Andrew Dunn, Jonathan Alexander Terrett, Jason Gary Sagert
Publikováno v:
Cancer Research. 80:879-879
Cancer patients that have undergone multiple lines of treatment can have dysfunctional immune systems. In both solid tumors and hematological malignancies, T cells have been reported to be in various states of dysfunction including senescence or exha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5750550a30fb562238bc147ed40c92e
https://doi.org/10.1158/1538-7445.am2020-879
https://doi.org/10.1158/1538-7445.am2020-879
Autor:
Mary-Lee Dequeant, Pooja Keerthipati, Tony W. Ho, Jonathan Alexander Terrett, Minh Thu Pham, Julie Carson, Ewelina Morawa, Zinkal Padalia, Matthias Will, Sushant Karnik
Publikováno v:
Cancer Research. 80:6595-6595
T cell lymphomas account for 10% to 15% of non-Hodgkin lymphomas and are diverse biologically and clinically. Unlike B-cell lymphomas, T cell lymphomas are rather resistant to conventional therapies, such as chemotherapy and antibody-based therapeuti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d14675a100d71ade8042d86c19d3a8b6
https://doi.org/10.1158/1538-7445.am2020-6595
https://doi.org/10.1158/1538-7445.am2020-6595
Autor:
Meghna Kuppuraju, Zinkal Padalia, Jonathan Alexander Terrett, Brigid McEwan, Demetrios Kalaitzidis
Publikováno v:
Cancer Research. 80:880-880
Hematologic malignancies have proven most responsive to CAR-T therapies. However, there is significant variability in the depth and duration of response to autologous CAR-T cells. Furthermore, CAR-T responses in solid malignancies have been minimal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdaa9cccfb486de4cefb28ba20faf6d0
https://doi.org/10.1158/1538-7445.am2020-880
https://doi.org/10.1158/1538-7445.am2020-880
Autor:
Zinkal Padalia, Ashley Porras, Mary Lee Dequeant, Jason Sagert, Thao Nguyen, Matthias John, Melanie Allen, Henia Dar, Daniel Henderson, Seshidar Police, Dakai Mu, Kelly Maeng, Elaine Huang, Sarah Spencer, Nickolaus Lorson, Paul Gonzales, Chelsea Holmquist, Gregg Hirschfeld, Jonathan A. Terrett, Demetrios Kalaitzidis
Publikováno v:
Cancer Research. 78:2551-2551
Autologous CAR T therapeutics have recently been approved for use in B-cell malignancies. While responses have been impressive using CD19 directed CAR T cells there has been a lack of comparable success for CAR T cells directed at solid tumor antigen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a69bd0c2af93fb403e26244a8c14c6bc
https://doi.org/10.1158/1538-7445.am2018-2551
https://doi.org/10.1158/1538-7445.am2018-2551
Autor:
Gábor Méhes, Peter Amersdorfer, David J. King, Jonathan Alexander Terrett, Sebastian Mannweiler, Slave Trajanoski
Publikováno v:
Pathology & Oncology Research. 15:167-172
Prostate-specific membrane antigen (PSMA) is a transmembrane protein that is overexpressed in advanced stage prostate adenocarcinomas. As a novel target for in vivo prognostic and therapeutic approaches, the distribution pattern of PSMA in primary an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d47d27a3ecf86e05430ea312aa2c133
https://doi.org/10.1007/s12253-008-9104-2
https://doi.org/10.1007/s12253-008-9104-2
Autor:
Mason S, Lu Ls, Boyd Rs, P J Adam, A C Stamps, Graham Steers, K C Gatter, Leach Bi, Stockwin L, Francesco Pezzella, G C Fletcher, J A Loader, Jonathan Alexander Terrett, Adrian L. Harris
Publikováno v:
British Journal of Cancer
In order to identify potential markers of renal cancer, the plasma membrane protein content of renal cell carcinoma (RCC)-derived cell lines was annotated using a proteomics process. One unusual protein identified at high levels in A498 and 786-O cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::741c4c8736c4c555723bd311c401758b
http://europepmc.org/articles/PMC2360640
http://europepmc.org/articles/PMC2360640
Autor:
Keith T. Wilson, San Lin Lou, Dee Aud, To Uyen T. Do, Sudha Swaminathan, Christian Rohlff, Jonathan Alexander Terrett, Alessandro Bressan, Giuseppe Merlino, Alessio Fiascarelli, Rachel L. Dusek, Monica Binaschi, Daniela Bellarosa, Corrado Carrisi, Arnima Bisht, Rahel Awdew
Publikováno v:
Cancer Research. 77:3646-3646
Ly75 (CD205, DEC-205) is a type I transmembrane glycoprotein and a C-type lectin receptor involved in antigen uptake and processing, mainly expressed by antigen presenting cells (APC). The short cytoplasmic tail contains motifs for amino acid-based e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7843d51ec1fe30ff5baeee06e35d05fe
https://doi.org/10.1158/1538-7445.am2017-3646
https://doi.org/10.1158/1538-7445.am2017-3646
Autor:
Jonathan Alexander Terrett, Joanne Rachel Evans, Eamonn O'Brien, William Cairns, Conrad Gerald Chapman, Hugh Jonathan Herdon, Israel S. Gloger
Publikováno v:
FEBS Letters. 463:301-306
Two forms of glycine transporter have been described to date, GlyT-1 and GlyT-2. The GlyT-2 form is expressed mainly in the spinal cord, brainstem and cerebellum. Here we describe the identification of a variant form of the human GlyT-2 (SC6), showin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08e0c583847e933a12e2343d0808adc5
https://doi.org/10.1016/s0014-5793(99)01636-1
https://doi.org/10.1016/s0014-5793(99)01636-1