Zobrazeno 1 - 10 of 413 pro vyhledávání: '"Jonathan Braun"'
1
Akademický článek
Crohn’s disease in endoscopic remission, obesity, and cases of high genetic risk demonstrates overlapping shifts in the colonic mucosal-luminal interface microbiome
Autor: Jonathan P. Jacobs, Maryam Goudarzi, Venu Lagishetty, Dalin Li, Tytus Mak, Maomeng Tong, Paul Ruegger, Talin Haritunians, Carol Landers, Philip Fleshner, Eric Vasiliauskas, Andrew Ippoliti, Gil Melmed, David Shih, Stephan Targan, James Borneman, Albert J. Fornace, Dermot P. B. McGovern, Jonathan Braun
Publikováno v: Genome Medicine, Vol 14, Iss 1, Pp 1-20 (2022)
Abstract Background Crohn’s disease (CD) patients demonstrate distinct intestinal microbial compositions and metabolic characteristics compared to unaffected controls. However, the impact of inflammation and underlying genetic risk on these microbi
Externí odkaz: https://doaj.org/article/fe92c4592aad437cb5c862f197cb01d1
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2
Akademický článek
Paradoxical sex-specific patterns of autoantibody response to SARS-CoV-2 infection
Autor: Yunxian Liu, Joseph E. Ebinger, Rowann Mostafa, Petra Budde, Jana Gajewski, Brian Walker, Sandy Joung, Min Wu, Manuel Bräutigam, Franziska Hesping, Elena Rupieper, Ann-Sophie Schubert, Hans-Dieter Zucht, Jonathan Braun, Gil Y. Melmed, Kimia Sobhani, Moshe Arditi, Jennifer E. Van Eyk, Susan Cheng, Justyna Fert-Bober
Publikováno v: Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-13 (2021)
Abstract Background Pronounced sex differences in the susceptibility and response to SARS-CoV-2 infection remain poorly understood. Emerging evidence has highlighted the potential importance of autoimmune activation in modulating the acute response a
Externí odkaz: https://doaj.org/article/7c3f66e3e6b044f8864813e5e1a63987
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3
Akademický článek
Magnetic resonance imaging for characterization of hepatocellular carcinoma metabolism
Autor: Lixia Wang, Ju Dong Yang, Charles C. Yoo, Keane K. Y. Lai, Jonathan Braun, Dermot P. B. McGovern, Yibin Xie, Stephen J. Pandol, Shelly C. Lu, Debiao Li
Publikováno v: Frontiers in Physiology, Vol 13 (2022)
With a better understanding of the pathophysiological and metabolic changes in hepatocellular carcinoma (HCC), multiparametric and novel functional magnetic resonance (MR) and positron emission tomography (PET) techniques have received wide interest
Externí odkaz: https://doaj.org/article/02527324461243f89230a510b70ca24f
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4
Akademický článek
Differences in SARS-CoV-2 Vaccine Response Dynamics Between Class-I- and Class-II-Specific T-Cell Receptors in Inflammatory Bowel Disease
Autor: Alexander M. Xu, Dalin Li, Joseph E. Ebinger, Emebet Mengesha, Rebecca Elyanow, Rachel M. Gittelman, Heidi Chapman, Sandy Joung, Gregory J. Botwin, Valeriya Pozdnyakova, Philip Debbas, Angela Mujukian, John C. Prostko, Edwin C. Frias, James L. Stewart, Arash A. Horizon, Noah Merin, Kimia Sobhani, Jane C. Figueiredo, Susan Cheng, Ian M. Kaplan, Dermot P. B. McGovern, Akil Merchant, Gil Y. Melmed, Jonathan Braun
Publikováno v: Frontiers in Immunology, Vol 13 (2022)
T-cells specifically bind antigens to induce adaptive immune responses using highly specific molecular recognition, and a diverse T-cell repertoire with expansion of antigen-specific clones can indicate robust immune responses after infection or vacc
Externí odkaz: https://doaj.org/article/b9f0c827dbb943ba89561bcaec2c555a
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5
Akademický článek
Longitudinal Characterisation of the Gastrointestinal Tract Microbiome in Systemic Sclerosis
Autor: Elizabeth R. Volkmann, Anna-Maria Hoffmann-Vold, Yu-Ling Chang, Venu Lagishetty, Philip J. Clements, Øyvind Midtvedt, Øyvind Molberg, Jonathan Braun, Jonathan P. Jacobs
Publikováno v: European Medical Journal, Vol 5, Iss 4, Pp 110-118 (2020)
Objectives: To evaluate changes in microbial composition and the evolution of gastrointestinal tract (GIT) symptoms in systemic sclerosis (SSc). Methods: Adult SSc patients provided stool specimens every 3 months over the course of 1 year. Partici
Externí odkaz: https://doaj.org/article/15b3795a6c504936ad4b459a49626fd5
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6
Akademický článek
Fungal microbiome in inflammatory bowel disease: a critical assessment
Autor: David M. Underhill, Jonathan Braun
Publikováno v: The Journal of Clinical Investigation, Vol 132, Iss 5 (2022)
The gut microbiome is at the center of inflammatory bowel disease (IBD) pathogenesis and disease activity. While this has mainly been studied in the context of the bacterial microbiome, recent advances have provided tools for the study of host geneti
Externí odkaz: https://doaj.org/article/1896883f11ee4e709605f7c6c3762dce
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8
Akademický článek
Space-type radiation induces multimodal responses in the mouse gut microbiome and metabolome
Autor: David Casero, Kirandeep Gill, Vijayalakshmi Sridharan, Igor Koturbash, Gregory Nelson, Martin Hauer-Jensen, Marjan Boerma, Jonathan Braun, Amrita K. Cheema
Publikováno v: Microbiome, Vol 5, Iss 1, Pp 1-18 (2017)
Abstract Background Space travel is associated with continuous low dose rate exposure to high linear energy transfer (LET) radiation. Pathophysiological manifestations after low dose radiation exposure are strongly influenced by non-cytocidal radiati
Externí odkaz: https://doaj.org/article/cb615717b6f34ad6ac2b1fa76bbb750f
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9
Akademický článek
Controlling for Contaminants in Low-Biomass 16S rRNA Gene Sequencing Experiments
Autor: Lisa Karstens, Mark Asquith, Sean Davin, Damien Fair, W. Thomas Gregory, Alan J. Wolfe, Jonathan Braun, Shannon McWeeney
Publikováno v: mSystems, Vol 4, Iss 4 (2019)
ABSTRACT Microbial communities are commonly studied using culture-independent methods, such as 16S rRNA gene sequencing. However, one challenge in accurately characterizing microbial communities is exogenous bacterial DNA contamination, particularly
Externí odkaz: https://doaj.org/article/89ae3b9ffc60409b9f8dc40bafba3212
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