Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Jonathan, Witton"'
Autor:
Vanessa I. Francis, Corin Liddle, Emma Camacho, Madhura Kulkarni, Samuel R. S. Junior, Jamie A. Harvey, Elizabeth R. Ballou, Darren D. Thomson, Gordon D. Brown, J. Marie Hardwick, Arturo Casadevall, Jonathan Witton, Carolina Coelho
Publikováno v:
mBio, Vol 15, Iss 4 (2024)
ABSTRACTCryptococcus neoformans causes lethal meningitis and accounts for approximately 10%–15% of AIDS-associated deaths worldwide. There are major gaps in our understanding of how this fungus invades the mammalian brain. To investigate the dynami
Externí odkaz:
https://doaj.org/article/fc389f2ba9944567b613ee2209d651cc
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 7, Pp 1417-1418 (2024)
Externí odkaz:
https://doaj.org/article/8bec1a21fbe847e0a66525b856e12693
Autor:
Erica S. Brady, Jessica Griffiths, Lilya Andrianova, Monika H. Bielska, Takashi Saito, Takaomi C. Saido, Andrew D. Randall, Francesco Tamagnini, Jonathan Witton, Michael T. Craig
Publikováno v:
Neurobiology of Disease, Vol 182, Iss , Pp 106151- (2023)
In the early stages of Alzheimer's disease (AD), the accumulation of the peptide amyloid-β (Aβ) damages synapses and disrupts neuronal activity, leading to the disruption of neuronal oscillations associated with cognition. This is thought to be lar
Externí odkaz:
https://doaj.org/article/9d519fa2f2764e72b12a5e04582bd6b0
Publikováno v:
eLife, Vol 12 (2023)
Externí odkaz:
https://doaj.org/article/29f203bde9ea417381d84ca61c0a531a
Publikováno v:
eLife, Vol 9 (2020)
Dementia is associated with severe spatial memory deficits which arise from dysfunction in hippocampal and parahippocampal circuits. For spatially sensitive neurons, such as grid cells, to faithfully represent the environment these circuits require p
Externí odkaz:
https://doaj.org/article/71ee70328f8f4fac9d68cfea99aae63d
Autor:
Johanna S. Jackson, Jonathan Witton, James D. Johnson, Zeshan Ahmed, Mark Ward, Andrew D. Randall, Michael L. Hutton, John T. Isaac, Michael J. O’Neill, Michael C. Ashby
Publikováno v:
Cell Reports, Vol 18, Iss 13, Pp 3063-3068 (2017)
Synapse loss is a key feature of dementia, but it is unclear whether synaptic dysfunction precedes degenerative phases of the disease. Here, we show that even before any decrease in synapse density, there is abnormal turnover of cortical axonal bouto
Externí odkaz:
https://doaj.org/article/c8d1c1bd56734a5daf6d3a26936978f0
Autor:
Callum Walsh, Thomas Ridler, Gabriella Margetts-Smith, Maria Garcia Garrido, Jonathan Witton, Andrew D. Randall, Jonathan T. Brown
Publikováno v:
J Neurosci
The retrosplenial cortex (RSC) plays a significant role in spatial learning and memory and is functionally disrupted in the early stages of Alzheimer's disease (AD). In order to investigate neurophysiological correlates of spatial learning and memory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::316ddd98fece249ef82d018da38f300e
https://doi.org/10.1523/jneurosci.0890-21.2022
https://doi.org/10.1523/jneurosci.0890-21.2022
Autor:
Erica S Brady, Jessica Griffiths, Lilya Andrianova, Takashi Saito, Takaomi C Saido, Andrew D Randall, Francesco Tamagnini, Jonathan Witton, Michael T Craig
In the early stages of Alzheimer’s disease (AD), the accumulation of the peptide amyloid-β (Aβ) damages synapses and disrupts neuronal activity and leads to disruption of neuronal oscillations associated with cognition. This is thought to be larg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f78944c32bd995413cac46f2bb3f8f0
https://doi.org/10.1101/2022.02.08.479119
https://doi.org/10.1101/2022.02.08.479119
Autor:
Andrew D. Randall, Maria Garcia Garrido, Jonathan Witton, Callum Walsh, Jonathan T. Brown, Thomas Ridler
The retrosplenial cortex (RSC) plays a significant role in spatial learning and memory, and is functionally disrupted in the early stages of Alzheimer’s disease. In order to investigate neurophysiological correlates of spatial learning and memory i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e763d4ac211251870ad662486d474400
https://doi.org/10.1101/2021.04.26.441462
https://doi.org/10.1101/2021.04.26.441462
Autor:
Lukasz Jankowski, Jonathan Witton, Soraya Meftah, Jonathan T. Brown, Michael C. Ashby, Annalisa Cavallini, Tracey K. Murray, Suchira Bose
Publikováno v:
Alzheimer's & Dementia. 16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c25accc365421ac36de09f07597897e1
https://doi.org/10.1002/alz.040342
https://doi.org/10.1002/alz.040342