Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Jonathan, Sun"'
Autor:
Inmaculada Ruz-Maldonado, John T. Gonzalez, Hanming Zhang, Jonathan Sun, Alicia Bort, Inamul Kabir, Richard G. Kibbey, Yajaira Suárez, Daniel M. Greif, Carlos Fernández-Hernando
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract Midlobular hepatocytes are proposed to be the most plastic hepatic cell, providing a reservoir for hepatocyte proliferation during homeostasis and regeneration. However, other mechanisms beyond hyperplasia have been little explored and the c
Externí odkaz:
https://doaj.org/article/464ecf555656487594404e7c594fa8c7
Autor:
Xinbo Zhang, Jonathan Sun, Alberto Canfrán-Duque, Binod Aryal, George Tellides, Ying Ju Chang, Yajaira Suárez, Timothy F. Osborne, Carlos Fernández-Hernando
Publikováno v:
JCI Insight, Vol 6, Iss 12 (2021)
Epigenetic modifications of the genome, including DNA methylation, histone methylation/acetylation, and noncoding RNAs, have been reported to play a fundamental role in regulating immune response during the progression of atherosclerosis. SETDB2 is a
Externí odkaz:
https://doaj.org/article/a3e168e7b1064f7b99f145e8a9e45c58
Autor:
Da Seul Yang, Maciej Barłóg, Jongsik Park, Kyeongwoon Chung, Apoorv Shanker, Jonathan Sun, Joonkoo Kang, Kwangyeol Lee, Mohammed Al-Hashimi, Jinsang Kim
Publikováno v:
ACS Omega, Vol 3, Iss 11, Pp 14807-14813 (2018)
Externí odkaz:
https://doaj.org/article/b80493c09bbe433180d05e88ebd36cb2
Autor:
Xinbo Zhang, Noemi Rotllan, Alberto Canfrán-Duque, Jonathan Sun, Jakub Toczek, Anna Moshnikova, Shipra Malik, Nathan L. Price, Elisa Araldi, Wen Zhong, Mehran M. Sadeghi, Oleg A. Andreev, Raman Bahal, Yana K. Reshetnyak, Yajaira Suárez, Carlos Fernández-Hernando
Publikováno v:
Circ Res
Background: miRNA therapeutics have gained attention during the past decade. These oligonucleotide treatments can modulate the expression of miRNAs in vivo and could be used to correct the imbalance of gene expression found in human diseases such as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfb733aafeaf7658bb00b0a0d274341d
https://doi.org/10.1161/circresaha.121.320296
https://doi.org/10.1161/circresaha.121.320296
Autor:
Pablo Fernández-Tussy, Jonathan Sun, Magdalena P. Cardelo, Nathan L. Price, Leigh Goedeke, Chrysovalantou E. Xirouchaki, Xiaoyong Yang, Oscar Pastor-Rojo, Anton M. Bennett, Tony Tiganis, Yajaira Suárez, Carlos Fernández-Hernando
Publikováno v:
bioRxiv
The complexity of the multiple mechanisms underlying non-alcoholic fatty liver disease (NAFLD) progression remains a significant challenge for the development of effective therapeutics. miRNAs have shown great promise as regulators of biological proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a685c6a02c0c1eb0bf66953c653aed
https://europepmc.org/articles/PMC9882318/
https://europepmc.org/articles/PMC9882318/
Autor:
Alberto Canfrán-Duque, Noemi Rotllan, Xinbo Zhang, Irene Andrés-Blasco, Bonne M. Thompson, Jonathan Sun, Nathan L. Price, Marta Fernández-Fuertes, Joseph W. Fowler, Diego Gómez-Coronado, William C. Sessa, Chiara Giannarelli, Robert J. Schneider, George Tellides, Jeffrey G. McDonald, Carlos Fernández-Hernando, Yajaira Suárez
Publikováno v:
Circulation.
Background: Cross-talk between sterol metabolism and inflammatory pathways has been demonstrated to significantly affect the development of atherosclerosis. Cholesterol biosynthetic intermediates and derivatives are increasingly recognized as key imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa74e5897ef6d86e6f9b054f929e1595
https://pubmed.ncbi.nlm.nih.gov/36416142
https://pubmed.ncbi.nlm.nih.gov/36416142
Autor:
Leigh A Goedeke, Xinbo Zhang, Jonathan Sun, Alberto Canfran-Duque, Noemi Rotllan, Ali Nasiri, Mario Kahn, Xian-Man Zhang, Carlos F Fernandez Hernando, Gerald Shulman
Publikováno v:
Circulation Research. 131
Atherosclerotic cardiovascular disease (CVD) remains a leading cause of morbidity and mortality in people with type 2 diabetes (T2D) and new therapies are urgently needed. We recently developed an orally available, liver-directed controlled-release m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::504673f29ecb31ce3a714849e4aa5c85
https://doi.org/10.1161/res.131.suppl_1.p3032
https://doi.org/10.1161/res.131.suppl_1.p3032
Autor:
Cornelius J. Clancy, Binghua Hao, M. Hong Nguyen, A. William Pasculle, Shaoji Cheng, Barry N. Kreiswirth, Ellen G Kline, Jonathan Sun, Ryan K. Shields, Liang Chen
Publikováno v:
Clin Infect Dis
Background Multidrug-resistant Enterobacterales (MDR-E), including carbapenem-resistant and third-generation cephalosporin-resistant Enterobacterales (CRE, CefR-E), are major pathogens following solid organ transplantation (SOT). Methods We prospecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fe6725dfa317370f5c274dd39e44eec
https://doi.org/10.1093/cid/ciab427
https://doi.org/10.1093/cid/ciab427
Autor:
Stanley Oyaghire, Sameet Mehta, Alanna R Kaplan, Balkrishna Chaube, Yajaira Suárez, Yana K. Reshetnyak, David L. Rimm, Peter M. Glazer, Nathan L. Price, Mahnaz Sahraei, Paolo Fiorina, Jonathan Sun, Yuting Liu, Carlos Fernández-Hernando, Rolando Garcia-Milian, Wen Ding, Raman Bahal
Publikováno v:
The Journal of Clinical Investigation
microRNA-21 (miR-21) is the most commonly upregulated miRNA in solid tumors. This cancer-associated microRNA (oncomiR) regulates various downstream effectors associated with tumor pathogenesis during all stages of carcinogenesis. In this study, we an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17592899f90ce870b9b851786c9ee917
http://europepmc.org/articles/PMC6877327
http://europepmc.org/articles/PMC6877327
Publikováno v:
Clocks & Sleep
Volume 1
Issue 3
Pages: 290-305
Clocks & sleep, vol 1, iss 3
Volume 1
Issue 3
Pages: 290-305
Clocks & sleep, vol 1, iss 3
Exposure of mice to a 24 h light:dark:light:dark (LDLD) cycle with dimly illuminated nights induces the circadian timing system to program two intervals of activity and two intervals of rest per 24 h cycle and subsequently allows entrainment to a var
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e77fd71b79251e4a24ff64f6b83df30
http://europepmc.org/articles/PMC7445826
http://europepmc.org/articles/PMC7445826