Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Jonathan, Ledoux"'
Autor:
Tao Wu, Yujia Wang, Wei Shi, Bi-Qi Zhang, John Raelson, Yu-Mei Yao, Huan-Dong Wu, Zao-Xian Xu, Francois-Christophe Marois-Blanchet, Jonathan Ledoux, Rikard Blunck, Jian-Zhong Sheng, Shen-Jiang Hu, Hongyu Luo, Jiangping Wu
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Ephb6 gene knockout causes hypertension in castrated mice. EPHB6 controls catecholamine secretion by adrenal gland chromaffin cells (AGCCs) in a testosterone-dependent way. Nicotinic acetylcholine receptor (nAChR) is a ligand-gated Ca2+/Na+ channel,
Externí odkaz:
https://doaj.org/article/50058466054c49f199650c56053df0e5
Autor:
Jonathan Béland, James Elber Duverger, Estelle Petitjean, Ange Maguy, Jonathan Ledoux, Philippe Comtois
Publikováno v:
AIP Advances, Vol 10, Iss 3, Pp 035133-035133-11 (2020)
A new open-hardware bioreactor capable of applying electrical field stimulation in conjunction with static or cyclic stretch is presented. Stretch is applied to cells by a specially designed elastomeric membrane with a central seeding region. The mai
Externí odkaz:
https://doaj.org/article/97b892ce204143f78e5df7b9c30bfd91
Autor:
Yohann Rautureau, Marianne Berlatie, Daniel Rivas, Kurunradeth Uy, Alexandre Blanchette, Géraldine Miquel, Marie-Ève Higgins, Mélanie Mecteau, Audrey Nault, Louis Villeneuve, Véronique Lavoie, Gabriel Théberge-Julien, Geneviève Brand, Line Lapointe, Maxime Denis, Camille Rosa, Annik Fortier, Lucie Blondeau, Marie-Claude Guertin, Marie-Pierre Dubé, Éric Thorin, Jonathan Ledoux, David Rhainds, Éric Rhéaume, Jean-Claude Tardif
Publikováno v:
Cardiovascular Research. 119:450-464
Aims The adenylate cyclase type 9 (ADCY9) gene appears to determine atherosclerotic outcomes in patients treated with dalcetrapib. In mice, we recently demonstrated that Adcy9 inactivation potentiates endothelial function and inhibits atherogenesis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59dfde35e0ca79a2cd243bb6960b41ac
https://doi.org/10.1093/cvr/cvac085
https://doi.org/10.1093/cvr/cvac085
Autor:
Vanessa Hertig, Kim Tardif, Marc Andre Meus, Natacha Duquette, Louis Villeneuve, Fanny Toussaint, Jonathan Ledoux, Angelino Calderone
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0176147 (2017)
Renal and lung fibrosis was characterized by the accumulation of collagen-immunoreactive mesenchymal cells expressing the intermediate filament protein nestin. The present study tested the hypothesis that nestin expression was increased in the hypert
Externí odkaz:
https://doaj.org/article/0b556b47b9ad4e10a72571505f4d0b7f
Autor:
Jonathan Boudreau-Béland, James Elber Duverger, Estelle Petitjean, Ange Maguy, Jonathan Ledoux, Philippe Comtois
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0127977 (2015)
In native conditions, cardiac cells must continuously comply with diverse stimuli necessitating a perpetual adaptation. Polydimethylsiloxane (PDMS) is commonly used in cell culture to study cellular response to changes in the mechanical environment.
Externí odkaz:
https://doaj.org/article/39a854bc21354e2fbd43726274447b00
Autor:
Delphine M Béziau, Fanny Toussaint, Alexandre Blanchette, Nour R Dayeh, Chimène Charbel, Jean-Claude Tardif, Jocelyn Dupuis, Jonathan Ledoux
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123769 (2015)
Phospholipase C (PLC) comprises a superfamily of enzymes that play a key role in a wide array of intracellular signalling pathways, including protein kinase C and intracellular calcium. Thirteen different mammalian PLC isoforms have been identified a
Externí odkaz:
https://doaj.org/article/108cee6842694178a0602809589d023d
Autor:
Jonathan Ledoux, Yanfen Shi, Jocelyn Dupuis, Mégane Tanguay, Nour R. Dayeh, Jean-Claude Tardif
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports
Scientific Reports
Pulmonary hypertension (PH) associated with left heart diseases is the most prevalent cause of PH. The scarcity of studies exploring the pathophysiology and therapies of group II PH resides in the lack of validated small animal models with non-invasi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10d703ac2c80f299f4d777c17a3cfee7
http://link.springer.com/article/10.1038/s41598-018-19625-2
http://link.springer.com/article/10.1038/s41598-018-19625-2
Autor:
David Rhainds, Eric Rhéaume, Marie-Ève Higgins, M Berlatie, Audrey Nault, Eric Thorin, Jonathan Ledoux, J.C. Tardif, Kurunradeth Uy, Yohann Rautureau, Daniel Rivas, Géraldine Miquel
Publikováno v:
European Heart Journal. 40
Background/Introduction The clinical benefits of the cholesterol ester transfer protein (CETP) inhibitor dalcetrapib are dependent on the ADCY9 gene, which encodes adenylate cyclase (AC) type 9 (AC9). AC9 is one of nine membrane-bound isoforms of AC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03a77f72c2f6e406743420d23119f505
https://doi.org/10.1093/eurheartj/ehz747.0324
https://doi.org/10.1093/eurheartj/ehz747.0324
Publikováno v:
Progress in Cardiovascular Diseases. 59(1):11-21
Left heart diseases (LHD) represent the most prevalent cause of pulmonary hypertension (PH), yet there are still no approved therapies that selectively target the pulmonary circulation in LHD. The increase in pulmonary capillary pressure due to LHD i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f4d1055efea1862b7285aebc9d2c58c
Autor:
James Elber Duverger, Jonathan Béland, Ange Maguy, Estelle Petitjean, Jonathan Ledoux, Philippe Comtois
Publikováno v:
AIP Advances, Vol 10, Iss 3, Pp 035133-035133-11 (2020)
Béland, Jonathan; Duverger, James Elber; Petitjean, Estelle; Maguy, Ange; Ledoux, Jonathan; Comtois, Philippe (2020). Development of an open hardware bioreactor for optimized cardiac cell culture integrating programmable mechanical and electrical stimulations. AIP Advances, 10(3), 035133. AIP Publishing 10.1063/1.5144922
Béland, Jonathan; Duverger, James Elber; Petitjean, Estelle; Maguy, Ange; Ledoux, Jonathan; Comtois, Philippe (2020). Development of an open hardware bioreactor for optimized cardiac cell culture integrating programmable mechanical and electrical stimulations. AIP Advances, 10(3), 035133. AIP Publishing 10.1063/1.5144922
A new open-hardware bioreactor capable of applying electrical field stimulation in conjunction with static or cyclic stretch is presented. Stretch is applied to cells by a specially designed elastomeric membrane with a central seeding region. The mai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7bcd3ea261aae964ea5e04ab4e8ac03
https://doaj.org/article/97b892ce204143f78e5df7b9c30bfd91
https://doaj.org/article/97b892ce204143f78e5df7b9c30bfd91