Zobrazeno 1 - 10
of 507
pro vyhledávání: '"Jonathan, Clayden"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/0f415f613814406aa70934955dbf2155
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-6 (2023)
Abstract The synthesis of biaryl compounds by the transition-metal free coupling of arenes is an important contemporary challenge, aiming to avoid the toxicity and cost profiles associated with the metal catalysts commonly used in the synthesis of th
Externí odkaz:
https://doaj.org/article/9ccdf55698314fa8ba454d9fe1651fe1
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-7 (2023)
Abstract Molecular biology achieves control over complex reaction networks by means of molecular systems that translate a chemical input (such as ligand binding) into an orthogonal chemical output (such as acylation or phosphorylation). We present an
Externí odkaz:
https://doaj.org/article/87f1d19e01b74c12baba99b83d9d6b2e
Autor:
Dr. Natasha Eccles, Dr. Flavio della Sala, Dr. Bryden A. F. Le Bailly, Dr. George F. S. Whitehead, Prof. Jonathan Clayden, Dr. Simon J. Webb
Publikováno v:
ChemistryOpen, Vol 9, Iss 3, Pp 338-345 (2020)
Abstract Two α‐aminoisobutyric acid (Aib) foldamers bearing Zn(II)‐chelating N‐termini have been synthesized and compared with a reported Aib foldamer that has a bis(quinolinyl)/mono(pyridyl) cap (BQPA group). Replacement of the quinolinyl arm
Externí odkaz:
https://doaj.org/article/e32f05420de04e728089c033c321a052
Autor:
David T. J. Morris, Jonathan Clayden
Publikováno v:
Chemical Society Reviews. 52:2480-2496
Helical oligomers devoid of configurational chirality can communicate information when an externally induced screw-sense preference propagates through the chain.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f662fb93463e5563732e68ef5b2e89b
https://doi.org/10.1039/d2cs00982j
https://doi.org/10.1039/d2cs00982j
Autor:
David T.J. Morris, Jonathan Clayden
Publikováno v:
Spectroscopy and Computation of Hydrogen‐Bonded Systems. :479-520
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f65cb1f553a2c7a062a31080d30d0b26
https://doi.org/10.1002/9783527834914.ch15
https://doi.org/10.1002/9783527834914.ch15
Publikováno v:
Wales, S M, Morris, D T J & Clayden, J 2022, ' Reversible Capture and Release of a Ligand Mediated by a Long-Range Relayed Polarity Switch in a Urea Oligomer ', Journal of the American Chemical Society, vol. 144, no. 7, pp. 2841-2846 . https://doi.org/10.1021/jacs.1c11928
Ethylene-bridged oligoureas characterized by a continuous, switchable chain of hydrogen bonds and carrying a binding site (an N,N'-disubstituted urea) for a hydrogen-bond-accepting ligand (a phosphine oxide) were synthesized. These oligomers show str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bce0c34c5db1071e6bc3dbfdeee4ddf3
https://doi.org/10.1021/jacs.1c11928
https://doi.org/10.1021/jacs.1c11928
Publikováno v:
Dynamic Kinetic Resolution (DKR) and Dynamic Kinetic Asymmetric Transformations (DYKAT) ISBN: 9783132453777
Stereoenriched atropisomeric compounds find important applications in various areas of chemistry and their synthesis is therefore a critical research target. This chapter presents a selection of the best methods available to date for the asymmetric p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28f95cc5676ea3249ed1bdfd5126d818
https://doi.org/10.1055/sos-sd-237-00162
https://doi.org/10.1055/sos-sd-237-00162
Publikováno v:
Watts, O F B, Berreur, J, Collins, B S L & Clayden, J 2022, ' Biocatalytic Enantioselective Synthesis of Atropisomers ', Accounts of Chemical Research, vol. 55, no. 23, pp. 3362-3375 . https://doi.org/10.1021/acs.accounts.2c00572, https://doi.org/10.1021/acs.accounts.2c00572
ConspectusAtropisomeric compounds are found extensively as natural products, as ligands for asymmetric transition-metal catalysis, and increasingly as bioactive and pharmaceutically relevant targets. Their enantioselective synthesis is therefore an i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f8f32c1b560a9326d9401b379b2e4c2
http://www.scopus.com/inward/record.url?scp=85141686378&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85141686378&partnerID=8YFLogxK
Autor:
Elliot H. E. Farrar, Steven M. Wales, John W. Ward, David Morris, Jonathan Clayden, David P Tilly, Matthew N. Grayson
Publikováno v:
Morris, D T J, Wales, S M, Tilly, D P, Farrar, E H E, Grayson, M N, Ward, J W & Clayden, J 2021, ' A molecular communication channel consisting of a single reversible chain of hydrogen bonds in a conformationally flexible oligomer ', Chem, pp. 2460-2472 . https://doi.org/10.1016/j.chempr.2021.06.022
Morris, D T J, Wales, S M, Tilly, D P, Farrar, E H E, Grayson, M N, Ward, J W & Clayden, J 2021, ' A molecular communication channel consisting of a single reversible chain of hydrogen bonds in a conformationally flexible oligomer ', Chem, vol. 7, no. 9, pp. 2460-2472 . https://doi.org/10.1016/j.chempr.2021.06.022
Chem
Morris, D T J, Wales, S M, Tilly, D P, Farrar, E H E, Grayson, M N, Ward, J W & Clayden, J 2021, ' A molecular communication channel consisting of a single reversible chain of hydrogen bonds in a conformationally flexible oligomer ', Chem, vol. 7, no. 9, pp. 2460-2472 . https://doi.org/10.1016/j.chempr.2021.06.022
Chem
Summary Communication of information through the global switching of conformation in synthetic molecules has hitherto entailed the inversion of chirality. Here, we report a class of oligomer through which information may be communicated through a glo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50d2a1096df31ba552f8d116fb143225
https://doi.org/10.1016/j.chempr.2021.06.022
https://doi.org/10.1016/j.chempr.2021.06.022