Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Jonathan, Amster"'
Autor:
Nana Shao, Yu Fan, Chau-Wen Chou, Shadi Yavari, Robert V. Williams, I. Jonathan Amster, Stuart M. Brown, Ian J. Drake, Evert C. Duin, William B. Whitman, Yuchen Liu
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
A heterologous protein expression platform in a culturable methanogen Methanococcus maripaludis is developed to study the methyl-coenzyme M reductase from uncultured archaea.
Externí odkaz:
https://doaj.org/article/bb2062aca74f47a48f99ab354429f323
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Human roundabout 1 (hRobo1) is an extracellular receptor glycoprotein that plays important roles in angiogenesis, organ development, and tumor progression. Interaction between hRobo1 and heparan sulfate (HS) has been shown to be essential fo
Externí odkaz:
https://doaj.org/article/e5321413ea7d40cc83bf25e0a020a745
Autor:
Marissa L. Maciej-Hulme, Jasper J. Van Gemst, Patience Sanderson, Angelique L. W. M. M. Rops, Jo H. Berden, Bart Smeets, I. Jonathan Amster, Ton J. Rabelink, Johan Van Der Vlag
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Proliferative forms of glomerulonephritis are characterized by the influx of leukocytes, albuminuria, and loss of kidney function. The glomerular endothelial glycocalyx is a thick carbohydrate layer that covers the endothelium and is comprised of hep
Externí odkaz:
https://doaj.org/article/5060c46b8253413ba7b4953347efe22b
Akademický článek
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Autor:
Elizabeth A. Lampros, Paul G. Kremer, Jesús S. Aguilar Díaz de León, Elijah T. Roberts, Maria Carolina Rodriguez Benavente, I. Jonathan Amster, Adam W. Barb
Publikováno v:
Current Research in Immunology, Vol 3, Iss , Pp 128-135 (2022)
The antibody-binding Fc γ receptors (FcγRs) trigger life-saving immune responses and many therapeutic monoclonal antibodies require FcγR engagement for full effect. One proven strategy to improve the efficacy of antibody therapies is to increase r
Externí odkaz:
https://doaj.org/article/7536861ddc37470b80ec0a0cb98ad2b3
Autor:
Amanda O. Shaver, Brianna M. Garcia, Goncalo J. Gouveia, Alison M. Morse, Zihao Liu, Carter K. Asef, Ricardo M. Borges, Franklin E. Leach, Erik C. Andersen, I. Jonathan Amster, Facundo M. Fernández, Arthur S. Edison, Lauren M. McIntyre
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Untargeted metabolomics studies are unbiased but identifying the same feature across studies is complicated by environmental variation, batch effects, and instrument variability. Ideally, several studies that assay the same set of metabolic features
Externí odkaz:
https://doaj.org/article/9d83b8419e124151806b3aaea729b8cd
Publikováno v:
Journal of Biomolecular NMR. 76:95-105
Autor:
Robert V. Williams, Chin Huang, Connor McDermott, Tanvir Ahmed, Linda Columbus, Kelley W. Moremen, James H. Prestegard, I. Jonathan Amster
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(43)
N -glycosylation is a common posttranslational modification of secreted proteins in eukaryotes. This modification targets asparagine residues within the consensus sequence, N–X–S/T. While this sequence is required for glycosylation, the initial t
A Taguchi Design of Experiments Approach for Untargeted Metabolomics Sample Preparation Optimization
Autor:
Brianna M. Garcia, Goncalo J. Gouveia, Amanda O. Shaver, Ricardo M. Borges, I. Jonathan Amster, Arthur S. Edison, Franklin E. Leach III
Metabolomics commonly uses analytical techniques such as nuclear magnetic resonance (NMR) and liquid chromatography coupled to mass spectrometry (LC-MS) to quantify and identify metabolites associated with biological variation. Metabolome coverage fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17ba456b7d5d56d2041589c01939e043
https://doi.org/10.26434/chemrxiv-2022-znvj7
https://doi.org/10.26434/chemrxiv-2022-znvj7
Publikováno v:
J Am Soc Mass Spectrom
Glycosaminoglycans (GAGs) are linear polysaccharides that participate in a broad range of biological functions. Their incomplete biosynthesis pathway leads to nonuniform chains and complex mixtures. For this reason, the characterization of GAGs has b